Research Topics
| X SagaertSummaryAffiliation: Katholieke Universiteit Leuven Country: Belgium Publications
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Detail Information
Publications
High-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy: a case reportFrederic Amant
Gynecologic Oncology, Leuven Cancer Institute LKI, Katholieke Universiteit Leuven, Belgium
J Med Case Reports 4:243. 2010..To the best of our knowledge, soft tissue sarcomas have not prevously been reported as a complication during pregnancy...- Gastric MALT lymphoma: a model of chronic inflammation-induced tumor developmentXavier Sagaert
Department of Pathology, University Hospitals of K U Leuven, Minderbroederstraat 12, B 3000 Leuven, Belgium
Nat Rev Gastroenterol Hepatol 7:336-46. 2010.... - Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programsXavier Sagaert
Section of Morphology and Molecular Pathology, Department of Pathology, Katholieke Universiteit Leuven, Leuven, Belgium
Mod Pathol 23:458-69. 2010.... - The dynamics of the B follicle: understanding the normal counterpart of B-cell-derived malignanciesX Sagaert
Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
Leukemia 21:1378-86. 2007..As such, this article aims to form an excellent base for a better understanding of the normal counterpart of B-cell-derived haematological malignancies (leukemias and lymphomas)... - The pathogenesis of MALT lymphomas: where do we stand?X Sagaert
Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
Leukemia 21:389-96. 2007..This review presents MALT lymphoma as a model of how sustained inflammation increases the risk of genotoxic insults and how these genetic events initiate oncogenesis... - Splenic marginal zone lymphoma-like features in API2-MALT1 transgenic mice that are exposed to antigenic stimulationXavier Sagaert
Department of Morphology and Molecular Pathology, University of Leuven, Leuven, Belgium
Haematologica 91:1693-6. 2006..These data indicate an effect of API2-MALT1 expression on the normal immune response... - Forkhead box protein P1 expression in mucosa-associated lymphoid tissue lymphomas predicts poor prognosis and transformation to diffuse large B-cell lymphomaXavier Sagaert
Department of Morphology and Molecular Pathology, and the Centre for Human Genetics, Catholic University Leuven, Leuven, Belgium
J Clin Oncol 24:2490-7. 2006..In this study, we investigated FOXP1 expression in its relationship to morphology, genetic features, and prognosis in a series of 70 MALT lymphomas... - MALT1 and BCL10 aberrations in MALT lymphomas and their effect on the expression of BCL10 in the tumour cellsXavier Sagaert
Division of Morphology and Molecular Pathology, Katholieke Universiteit Leuven, Leuven, Belgium
Mod Pathol 19:225-32. 2006.... - Classification of B-cells according to their differentiation status, their micro-anatomical localisation and their developmental lineageXavier Sagaert
Department of Morphology and Molecular Pathology KU Leuven, Aspirant FWO Flanders, Minderbroederstraat 12, 3000 Leuven, Belgium
Immunol Lett 90:179-86. 2003..In this review, we will discuss the various subsets of B-cells and point to the similarities between the various classification systems in use... - Subclinical GvHD in non-irradiated F1 hybrids: severe lymphoid-tissue GvHD causing prolonged immune dysfunctionB Sprangers
Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium
Bone Marrow Transplant 46:586-96. 2011.... - Allogeneic bone marrow transplantation and donor lymphocyte infusion in a mouse model of irradiation-induced myelodysplastic/myeloproliferation syndrome (MD/MPS): evidence for a graft-versus-MD/MPS effectB Sprangers
Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium
Leukemia 23:340-9. 2009..However, severe DLI-induced acute graft-versus-host disease occurred, precluding a survival advantage. We present evidence of the existence of a post-alloBMT DLI-induced graft-versus-MD/MPS effect in murine irradiation-induced MD/MPS... - FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrationsI Wlodarska
Center for Human Genetics, Katholieke Universiteit Leuven, Leuven, Belgium
Leukemia 19:1299-305. 2005..However, over-representation of the FOXP1 locus found in one additional case of DLBCL may represent another potential mechanism underlying an increased expression of this gene... - CTLA-4 blockade in murine bone marrow chimeras induces a host-derived antileukemic effect without graft-versus-host diseaseS Fevery
Laboratory of Experimental Transplantation, University of Leuven, Leuven, Belgium
Leukemia 21:1451-9. 2007..Our findings reveal the potential of using CTLA-4 blockade to establish antileukemic effects after allogeneic hematopoietic stem cell transplantation, provided autoimmunity can be controlled... - Posttransplant Epstein-Barr virus-associated myogenic tumors: case report and review of the literatureB Sprangers
Department of Nephrology, University Hospital Gasthuisberg, Leuven, Belgium
Am J Transplant 8:253-8. 2008..A case of a 51-year-old kidney transplant recipient diagnosed with EBV-SMT is reported together with a review of the literature... - Selective expansion of marginal zone B cells in Emicro-API2-MALT1 mice is linked to enhanced IkappaB kinase gamma polyubiquitinationMathijs Baens
Center for Human Genetics, Molecular Genetics, Flanders Interuniversity Institute for Biotechnology, Catholic University of Leuven, Leuven, Belgium
Cancer Res 66:5270-7. 2006..Taken together, these data support the hypothesis that the API2-MALT1 fusion protein can contribute to MALT lymphoma formation via increased NF-kappaB activation...