Gunnar M Buyse

Summary

Affiliation: Katholieke Universiteit Leuven
Country: Belgium

Publications

  1. ncbi Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring
    G Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Belgium
    Neurology 60:1679-81. 2003
  2. ncbi CINRG pilot trial of oxatomide in steroid-naïve Duchenne muscular dystrophy
    Gunnar M Buyse
    University Hospitals KU Leuven, Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Eur J Paediatr Neurol 11:337-40. 2007
  3. ncbi Idebenone as a novel, therapeutic approach for Duchenne muscular dystrophy: results from a 12 month, double-blind, randomized placebo-controlled trial
    Gunnar M Buyse
    Child Neurology, University Hospitals Leuven, Leuven, Belgium
    Neuromuscul Disord 21:396-405. 2011
  4. ncbi Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance
    Gunnar M Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Herestraat, Leuven, Belgium
    Eur Heart J 30:116-24. 2009

Detail Information

Publications4

  1. ncbi Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring
    G Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Belgium
    Neurology 60:1679-81. 2003
    ..Idebenone reduced erythrocyte protoporphyrin IX levels in five of six patients with elevated baseline levels; however, changes did not consistently relate to cardiac improvement...
  2. ncbi CINRG pilot trial of oxatomide in steroid-naïve Duchenne muscular dystrophy
    Gunnar M Buyse
    University Hospitals KU Leuven, Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Eur J Paediatr Neurol 11:337-40. 2007
    ..A modest mitigation of strength deterioration over time cannot be excluded...
  3. ncbi Idebenone as a novel, therapeutic approach for Duchenne muscular dystrophy: results from a 12 month, double-blind, randomized placebo-controlled trial
    Gunnar M Buyse
    Child Neurology, University Hospitals Leuven, Leuven, Belgium
    Neuromuscul Disord 21:396-405. 2011
    ..042 for PEF percent predicted). Limitations of this study were the small sample size, and a skewed age distribution between treatment groups. Data from this study provided the basis for the planning of a confirmatory study...
  4. ncbi Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance
    Gunnar M Buyse
    Department of Pediatric Neurology, University Hospitals Leuven, Herestraat, Leuven, Belgium
    Eur Heart J 30:116-24. 2009
    ..We have performed such a trial of SNT-MC17/idebenone in the mdx mouse model of DMD, based on the drug's potential to improve mitochondrial respiratory chain function and reduce oxidative stress...