Research Topics
| Xavier GeetsSummaryCountry: Belgium Publications
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Detail Information
Publications
Adaptive biological image-guided IMRT with anatomic and functional imaging in pharyngo-laryngeal tumors: impact on target volume delineation and dose distribution using helical tomotherapyXavier Geets
Department of Radiation Oncology, Universite Catholique de Louvain, Brussels, Belgium
Radiother Oncol 85:105-15. 2007....
A gradient-based method for segmenting FDG-PET images: methodology and validationXavier Geets
Department of Radiation Oncology, Center for Molecular Imaging and Experimental Radiotherapy, Universite Catholique de Louvain, St Luc University Hospital, 1200, Brussels, Belgium
Eur J Nucl Med Mol Imaging 34:1427-38. 2007..A new gradient-based method for segmenting FDG-PET images is described and validated...
Impact of the type of imaging modality on target volumes delineation and dose distribution in pharyngo-laryngeal squamous cell carcinoma: comparison between pre- and per-treatment studiesXavier Geets
Department of Radiation Oncology and Head and Neck Oncology Program, , Brussels, Belgium
Radiother Oncol 78:291-7. 2006..CONCLUSIONS: The use of pre-treatment FDG-PET and per-treatment CT or MRI significantly impacts on the delineation of TVs in pharyngo-laryngeal SCC, translating into more normal tissue sparing after conformal radiotherapy planning...
Evaluation of the radiobiological impact of anatomic modifications during radiation therapy for head and neck cancer: can we simply summate the dose?Jonathan Orban de Xivry
ICTEAM Institute, Universite Catholique de Louvain, Louvain la Neuve, Belgium
Radiother Oncol 96:131-8. 2010..This study evaluates practically if the accumulation of all of these registered dose fractions must take radiobiology into account in a classical clinical setting...
PET-based treatment planning in radiotherapy: a new standard?Vincent Gregoire
Radiation Oncology Department, Universite Catholique de Louvain, St Luc University Hospital, Brussels, Belgium
J Nucl Med 48:68S-77S. 2007..This review discusses how PET/CT might modify the current state of the art of radiotherapy planning...
Adaptive radiotherapy of head and neck cancerPierre Castadot
Department of Radiation Oncology, Center for Molecular Imaging and Experimental Radiotherapy, Universite Catholique de Louvain, St Luc University Hospital, Brussels, Belgium
Semin Radiat Oncol 20:84-93. 2010..This article reviews the causes and discusses potential solutions to circumvent the discrepancies between the planned dose and the actual dose received by patients treated for H&N malignancies...
Comparison of 12 deformable registration strategies in adaptive radiation therapy for the treatment of head and neck tumorsPierre Castadot
Department of Radiation Oncology, Universite Catholique de Louvain, St Luc University Hospital, Brussels, Belgium
Radiother Oncol 89:1-12. 2008..It however requires the use of specific deformable registration (DR) algorithms that requires proper validation on a clinical material...
Adaptive functional image-guided IMRT in pharyngo-laryngeal squamous cell carcinoma: is the gain in dose distribution worth the effort?Pierre Castadot
Department of Radiation Oncology, Universite Catholique de Louvain, Brussels, Belgium
Radiother Oncol 101:343-50. 2011....
Is PET-based treatment planning the new standard in modern radiotherapy? The head and neck paradigmVincent Gregoire
Department of Radiation Oncology and Center for Molecular Imaging and Experimental Radiotherapy, Universite Catholique de Louvain, St Luc University Hospital, Brussels, Belgium
Semin Radiat Oncol 16:232-8. 2006..Therefore, although integration of PET images into the radiotherapy process seems promising, for the moment it should remain in the research arena...
Gradient-based delineation of the primary GTV on FDG-PET in non-small cell lung cancer: a comparison with threshold-based approaches, CT and surgical specimensMarie Wanet
Department of Radiation Oncology, Center of Molecular Imaging and Experimental Radiotherapy, Universite Catholique de Louvain, Brussels, Belgium
Radiother Oncol 98:117-25. 2011..The aim of this study was to validate a gradient-based segmentation method for GTV delineation on FDG-PET in NSCLC through surgical specimen, in comparison with threshold-based approaches and CT...
Inter-observer variability in the delineation of pharyngo-laryngeal tumor, parotid glands and cervical spinal cord: comparison between CT-scan and MRIXavier Geets
Department of Radiation Oncology, , St-Luc University Hospital, Brussels, Belgium
Radiother Oncol 77:25-31. 2005..001) and between modalities (P<0.001) (CT: 34.8, 29.4, and 26.8 ml; MRI: 30.6, 27.9 and 20.4 ml). Similar results were obtained for mean spinal cord volumes (CT: 10.7, 10.6, and 9.5 ml; MRI: 8.7, 8.5 and 8.2 ml; P=0.05)...
Assessment by a deformable registration method of the volumetric and positional changes of target volumes and organs at risk in pharyngo-laryngeal tumors treated with concomitant chemo-radiationPierre Castadot
Department of Radiation Oncology, Center for Molecular Imaging and Experimental Radiotherapy IMRE, Universite Catholique de Louvain, Belgium
Radiother Oncol 95:209-17. 2010..Anatomic (CT) and functional (FDG-PET) imaging were used for the delineation of the GTVs...
Efficient multi-modal dense field non-rigid registration: alignment of histological and section imagesAloys du Bois d'Aische
Communications and Remote Sensing Laboratory, Universite Catholique de Louvain, B 1348 Louvain la Neuve, Belgium
Med Image Anal 9:538-46. 2005..A further acceleration in speed without cost of accuracy is achieved by using an adaptive mesh refinement strategy...
Selection and delineation of target volumes in head and neck tumors: beyond ICRU definitionVincent Gregoire
Radiation Oncology Department, Laboratory of Radiobiology, Universite Catholique de Louvain, St Luc University Hospital, Bruxelles, Belgium
Rays 28:217-24. 2003..The present manuscript intends to review available data on selection and delineation of target volumes for primary tumor and neck nodes. Setup uncertainties and how they influence the PTV delineation are also discussed...
Lung cancer: Morphological and functional approach to screening, staging and treatment planningEmmanuel Coche
Department of Medical Imaging, Universite Catholique de Louvain, Cliniques Universitaires St Luc, Brussels, Belgium
Future Oncol 6:367-80. 2010..For treatment planning, flurodeoxglucose PET-CT is playing an increasing role in radiotherapy planning at the target selection and definition steps...
Edge-preserving filtering of images with low photon countsJohn A Lee
Molecular Imaging and Experimental Radiotherapy Unit IMRE, Universite Catholique de Louvain, Brussels Belgium
IEEE Trans Pattern Anal Mach Intell 30:1014-27. 2008..Experiments show that ensuring the photometry invariance leads to comparable denoising performances in terms of the root mean square error computed on the signal...
Role of 11-C-methionine positron emission tomography for the delineation of the tumor volume in pharyngo-laryngeal squamous cell carcinoma: comparison with FDG-PET and CTXavier Geets
Department of Radiotherapy, Cliniques Universitaires Saint-Luc, UCL Medical School, Avenue Hippocrate 10, B-1200 Brussels, Belgium
Radiother Oncol 71:267-73. 2004..On the contrary, MET-PET does not have any additional value since MET volumes are not different from CT volumes, probably because of the high uptake of MET by the normal mucosa and salivary glands surrounding the tumor...
Comparison of CT- and FDG-PET-defined GT: in regard to Paulino et al. (Int J Radiat Oncol Biol Phys 2005;61:1385-1392)Vincent Gregoire
Int J Radiat Oncol Biol Phys 63:308-9; author reply 309. 2005
