Jacques Brotchi

Summary

Country: Belgium

Publications

  1. ncbi Intrinsic spinal cord tumor resection
    Jacques Brotchi
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 50:1059-63. 2002
  2. ncbi [The neurosurgery department]
    J Brotchi
    Rev Med Brux 23:123-6. 2002
  3. ncbi Clinical impact of integrating positron emission tomography during surgery in 85 children with brain tumors
    Benoit J M Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808, Route de Lennik, B 1070 Brussels, Belgium
    J Neurosurg Pediatr 5:486-99. 2010
  4. ncbi Clinical interest of integrating positron emission tomography imaging in the workup of 55 children with incidentally diagnosed brain lesions
    Benoit J M Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808, Route de Lennik, B 1070 Brussels, Belgium
    J Neurosurg Pediatr 5:479-85. 2010
  5. ncbi Integrated positron emission tomography and magnetic resonance imaging-guided resection of brain tumors: a report of 103 consecutive procedures
    Benoit Pirotte
    Department of Neurosurgery, PET Cyclotron Biomédical Unit, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    J Neurosurg 104:238-53. 2006
  6. ncbi Integration of [11C]methionine-positron emission tomographic and magnetic resonance imaging for image-guided surgical resection of infiltrative low-grade brain tumors in children
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 57:128-39; discussion 128-39. 2005
  7. ncbi Comparison of functional MR imaging guidance to electrical cortical mapping for targeting selective motor cortex areas in neuropathic pain: a study based on intraoperative stereotactic navigation
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, University of Brussels, Brussels, Belgium
    AJNR Am J Neuroradiol 26:2256-66. 2005
  8. ncbi Positron emission tomography-guided volumetric resection of supratentorial high-grade gliomas: a survival analysis in 66 consecutive patients
    Benoit J M Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 64:471-81; discussion 481. 2009
  9. ncbi Combined use of 18F-fluorodeoxyglucose and 11C-methionine in 45 positron emission tomography-guided stereotactic brain biopsies
    Benoit Pirotte
    Department of Neurosurgery, PET Biomedical Cyclotron Unit, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Neurosurg 101:476-83. 2004
  10. ncbi PET imaging in the surgical management of pediatric brain tumors
    Benoit Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808 Route de Lennik, 1070, Brussels, Belgium
    Childs Nerv Syst 23:739-51. 2007

Collaborators

Detail Information

Publications69

  1. ncbi Intrinsic spinal cord tumor resection
    Jacques Brotchi
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 50:1059-63. 2002
    ..Meticulous nonbleeding surgery and experience are the keys to success...
  2. ncbi [The neurosurgery department]
    J Brotchi
    Rev Med Brux 23:123-6. 2002
    ....
  3. ncbi Clinical impact of integrating positron emission tomography during surgery in 85 children with brain tumors
    Benoit J M Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808, Route de Lennik, B 1070 Brussels, Belgium
    J Neurosurg Pediatr 5:486-99. 2010
    ..In this paper, the authors' goal was to evaluate the impact of PET information on brain tumor surgery in children...
  4. ncbi Clinical interest of integrating positron emission tomography imaging in the workup of 55 children with incidentally diagnosed brain lesions
    Benoit J M Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808, Route de Lennik, B 1070 Brussels, Belgium
    J Neurosurg Pediatr 5:479-85. 2010
    ..In this paper, the authors' goal was to evaluate the impact of PET data on the clinical management of incidental brain lesions in children...
  5. ncbi Integrated positron emission tomography and magnetic resonance imaging-guided resection of brain tumors: a report of 103 consecutive procedures
    Benoit Pirotte
    Department of Neurosurgery, PET Cyclotron Biomédical Unit, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    J Neurosurg 104:238-53. 2006
    ..The aim of this study was to evaluate the integration of positron emission tomography (PET) scanning data into the image-guided resection of brain tumors...
  6. ncbi Integration of [11C]methionine-positron emission tomographic and magnetic resonance imaging for image-guided surgical resection of infiltrative low-grade brain tumors in children
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 57:128-39; discussion 128-39. 2005
    ..To evaluate the interest of integrating positron emission tomography (PET) images with the radiolabeled tracer [(11)C]methionine (Met) into the image-guided navigation planning of infiltrative low-grade brain tumors (LGBTs) in children...
  7. ncbi Comparison of functional MR imaging guidance to electrical cortical mapping for targeting selective motor cortex areas in neuropathic pain: a study based on intraoperative stereotactic navigation
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, University of Brussels, Brussels, Belgium
    AJNR Am J Neuroradiol 26:2256-66. 2005
    ..These data illustrate the functional accuracy of fMRI guidance for the operative targeting of selective motor cortex areas in neuropathic pain...
  8. ncbi Positron emission tomography-guided volumetric resection of supratentorial high-grade gliomas: a survival analysis in 66 consecutive patients
    Benoit J M Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 64:471-81; discussion 481. 2009
    ..The present study aims to evaluate whether PET-guided volumetric resection (VR) in supratentorial HGG might add benefit to the patient's outcome...
  9. ncbi Combined use of 18F-fluorodeoxyglucose and 11C-methionine in 45 positron emission tomography-guided stereotactic brain biopsies
    Benoit Pirotte
    Department of Neurosurgery, PET Biomedical Cyclotron Unit, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Neurosurg 101:476-83. 2004
    ..The aim of this study was to compare the contribution of the tracers 11C-methionine (Met) and 18F-fluorodeoxy-glucose (FDG) in positron emission tomography (PET)-guided stereotactic brain biopsy...
  10. ncbi PET imaging in the surgical management of pediatric brain tumors
    Benoit Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, 808 Route de Lennik, 1070, Brussels, Belgium
    Childs Nerv Syst 23:739-51. 2007
    ..The present article illustrates whether positron-emission tomography (PET) imaging may improve the surgical management of pediatric brain tumors (PBT) at different steps...
  11. ncbi Irradiation of cochlear structures during vestibular schwannoma radiosurgery and associated hearing outcome
    Nicolas Massager
    Gamma Knife Center, University Hospital Erasme, Brussels, Belgium
    J Neurosurg 107:733-9. 2007
    ....
  12. ncbi Positron emission tomography for the early postsurgical evaluation of pediatric brain tumors
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Belgium
    Childs Nerv Syst 21:294-300. 2005
    ..The object was to study the value of postoperative positron emission tomography (PET) to assess the extension of brain tumor resection...
  13. ncbi Brain stem metastases treated with radiosurgery: prognostic factors of survival and life expectancy estimation
    José G Lorenzoni
    Department of Neurosurgery, Hopital Erasme, Gamma Knife Center, Universite Libre de Bruxelles, 1000 Brussels, Belgium
    Surg Neurol 71:188-95; discussion 195, 195-6. 2009
    ..The objective of this study is to study prognostic factors of survival and 3 stratification systems for life expectancy estimation in patients with brain stem metastases treated with radiosurgery...
  14. ncbi Use of the Leksell gamma knife C with automatic positioning system for the treatment of meningioma and vestibular schwannoma
    Marc Levivier
    Centre Gamma Knife of the Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurg Focus 14:e8. 2003
    ..The authors report their experience using the Leksell gamma knife C (GK-C) for the treatment of meningioma and vestibular schwannoma (VS)...
  15. ncbi Differential transgene expression profiles in rat brain, using rAAV2/1 vectors with tetracycline-inducible and cytomegalovirus promoters
    Olivier Bockstael
    Multidisciplinary Research Institute IRIBHM, Universite Libre de Bruxelles, Hopital Erasme, Brussels, Belgium
    Hum Gene Ther 19:1293-305. 2008
    ..We conclude that the rAAV2/1-TetON vector constitutes an interesting tool for specific transgene expression in midbrain dopaminergic neurons...
  16. ncbi Role of intracanalicular volumetric and dosimetric parameters on hearing preservation after vestibular schwannoma radiosurgery
    Nicolas Massager
    Gamma Knife Center, Erasme Hospital, Université Libre de Brixelles, Brussels, Belgium
    Int J Radiat Oncol Biol Phys 64:1331-40. 2006
    ..To analyze the relationship between hearing preservation after gamma knife radiosurgery (GKR) for vestibular schwannoma (VS) and some volumetric and dosimetric parameters of the intracanalicular components of VS...
  17. ncbi Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model
    Xin Yang
    Laboratory of Experimental Neurosurgery, Universite Libre de Bruxelles, Brussels, Belgium
    J Gene Med 11:899-912. 2009
    ..By contrast, the neurorestorative effects of GDNF administered several weeks after the toxin have been less characterized. In particular, whether these were permanent or dependent on the continuous presence of GDNF remains elusive...
  18. ncbi Endovascular treatment of middle cerebral artery aneurysms
    Boris Lubicz
    Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium
    Neurocrit Care 5:93-101. 2006
    ..We prospectively evaluated the feasibility and the results of EVT when it is considered as the first therapeutic option for the treatment of MCA aneurysms...
  19. ncbi Preliminary experience with the enterprise stent for endovascular treatment of complex intracranial aneurysms: potential advantages and limiting characteristics
    Boris Lubicz
    Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium
    Neurosurgery 62:1063-9; discussion 1069-70. 2008
    ..The aim of this study was to evaluate the use of this stent for EVT of complex aneurysms...
  20. ncbi Comparison of 18F-FDG and 11C-methionine for PET-guided stereotactic brain biopsy of gliomas
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    J Nucl Med 45:1293-8. 2004
    ..We compared the contributions of the labeled tracers (11)C-methionine (Met) and (18)F-FDG for PET-guided stereotactic biopsy of brain gliomas...
  21. ncbi Selective image-guided venous sinus exposure for direct embolization of dural arteriovenous fistula: technical case report
    Michael Bruneau
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, Brussels 1070, Belgium
    Surg Neurol 69:192-6; discussion 196. 2008
    ..Large craniectomies carry nevertheless a risk of postembolization extradural hematoma, reduced by delaying the endovascular procedure. We report a 1-session technique of SIGC for percutaneous transvenous DAVF embolization...
  22. ncbi Circumferential and fusiform intracranial aneurysms: reconstructive endovascular treatment with self-expandable stents
    Boris Lubicz
    Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium
    Neuroradiology 50:499-507. 2008
    ..We report our experience with endovascular treatment (EVT) of circumferential and fusiform intracranial aneurysms by a reconstructive approach with self-expandable stents...
  23. ncbi Persistent hydrocephalus after early surgical management of posterior fossa tumors in children: is routine preoperative endoscopic third ventriculostomy justified?
    Daniele Morelli
    Department of Neurosurgery, Erasme Hospital, Universit, Libre de Bruxelles, Brussels, Belgium
    J Neurosurg 103:247-52. 2005
    ..For preventing it, however, they recommend early posterior fossa surgery whenever possible. The low rate of persistent hydrocephalus does not justify adopting routine preoperative ETVs...
  24. ncbi Preliminary personal experiences with the application of near-infrared indocyanine green videoangiography in extracranial vertebral artery surgery
    Michael Bruneau
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 66:305-11; discussion 311. 2010
    ..We evaluated the feasibility, usefulness, and limitations of near-infrared indocyanine green (ICG) videoangiography during procedures involving the extracranial vertebral artery (VA)...
  25. ncbi Long-term follow-up survey reveals a high yield, up to 30% of patients presenting newly detected aneurysms more than 10 years after ruptured intracranial aneurysms clipping
    Michael Bruneau
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurg Rev 34:485-96. 2011
    ..In conclusion, based on a 30% rate of new aneurysm formation in patients clipped more than a decade ago, close screening on a very long-term perspective is encouraged. This study suggests aneurysm formation to be a continuous process...
  26. ncbi Surgery of intraspinal cord tumors
    Jacques Brotchi
    Department of Neurosurgery, Erasme Hospital-ULB, Brussels, Belgium
    Clin Neurosurg 53:209-16. 2006
  27. ncbi Lack of minocycline efficiency in genetic models of Huntington's disease
    Stephane Mievis
    IRIBHM, Brussels, Belgium
    Neuromolecular Med 9:47-54. 2007
    ..Altogether, the present data does not support minocycline as a beneficial drug for HD...
  28. ncbi Management of anterolateral foramen magnum meningiomas: surgical vs conservative decision making
    Benoit J M Pirotte
    Department of Neurosurgery, Erasme Hospital, University of Brussels, Brussels, Belgium
    Neurosurgery 67:ons58-70; discussion ons70. 2010
    ..Anterolateral meningiomas of the foramen magnum (FMMs) represent a neurosurgical challenge because they grow in close contact with osteoarticular, nervous, and vascular structures that cannot be sacrificed or retracted...
  29. ncbi Monitoring the expression profiles of integrins and adhesion/growth-regulatory galectins in adamantinomatous craniopharyngiomas: their ability to regulate tumor adhesiveness to surrounding tissue and their contribution to prognosis
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital, Brussels, Belgium
    Neurosurgery 56:763-76. 2005
    ..In addition, a Cox regression analysis has revealed that the levels of galectin-4 contribute significant information toward the delay in recurrence independently of surgical status...
  30. ncbi Cimetidine, an unexpected anti-tumor agent, and its potential for the treatment of glioblastoma (review)
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital, Brussels, Belgium
    Int J Oncol 28:1021-30. 2006
    ....
  31. ncbi Capillary hemangioma in the superior sagittal sinus as a rare cause of intracranial hypertension in a child: case report
    Jacques Brotchi
    Department of Neurosurgery, Erasme Hospital, Free University of Brussels, Brussels, Belgium
    Neurosurgery 57:E815. 2005
    ..This case emphasizes the importance of multiple complementary imaging modalities and the efficacy of a direct surgical approach, which allowed resolution of symptoms...
  32. ncbi Combination of functional magnetic resonance imaging-guided neuronavigation and intraoperative cortical brain mapping improves targeting of motor cortex stimulation in neuropathic pain
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 56:344-59; discussion 344-59. 2005
    ....
  33. ncbi Recombinant AAV viral vectors serotype 1, 2, and 5 mediate differential gene transfer efficiency in rat striatal fetal grafts
    Alphonse Lubansu
    Laboratory of Experimental Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Cell Transplant 16:1013-20. 2008
    ..Our study suggests that GE transduced by rAAV-serotype 1 vectors could be an interesting tool to mediate efficient expression of a gene coding a neurotrophic factor in Huntington's disease...
  34. ncbi Cerebral anaplastic pleomorphic xanthoastrocytoma with meningeal dissemination at first presentation
    Alphonse Lubansu
    Department of Neurosurgery, , , 808 Route de Lennik, 1070 Brussels, Belgium
    Childs Nerv Syst 20:119-22. 2004
    ..CASE REPORT: We describe the case of a cerebral PXA in a 7-year-old girl presenting with anaplastic histological features and craniospinal meningeal dissemination that progressed rapidly with a poor outcome...
  35. ncbi Combined positron emission tomography and magnetic resonance imaging for the planning of stereotactic brain biopsies in children: experience in 9 cases
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Pediatr Neurosurg 38:146-55. 2003
    ....
  36. ncbi Gamma knife surgery for idiopathic trigeminal neuralgia performed using a far-anterior cisternal target and a high dose of radiation
    Nicolas Massager
    Gamma Knife Center, Department of Neurosurgery, Erasme Hospital, Brussels, Belgium
    J Neurosurg 100:597-605. 2004
    ..The authors analyzed the results of GKS in which a high dose of radiation and a distal target was used, to determine the best parameters for this treatment...
  37. ncbi The integration of metabolic imaging in stereotactic procedures including radiosurgery: a review
    Marc Levivier
    Centre Gamma Knife, Université Libre de Bruxelle, Départmente de Neurochirurgie, PET Cyclotron Biomedical, Hopital Erasme, Bruxelle, Belgique
    J Neurosurg 97:542-50. 2002
    ..The authors review their experience with the clinical development and routine use of positron emission tomography (PET) during stereotactic procedures, including the use of PET-guided gamma knife radiosurgery (GKS)...
  38. ncbi Fluorodeoxyglucose and methionine uptake in Lhermitte-Duclos disease: case report
    Benoit Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 50:404-7; discussion 407-8. 2002
    ....
  39. ncbi PoleStar N-10 low-field compact intraoperative magnetic resonance imaging system with mobile radiofrequency shielding
    Marc Levivier
    Department of Neurosurgery, Universite Libre de Bruxelles Hopital Erasme, Brussels, Belgium
    Neurosurgery 53:1001-6; discussion 1007. 2003
    ..The cost of the PoleStar N-10 ranges from $900,000 to $1,050,000, depending on options. The price of the mobile radiofrequency shielding option is $80,000...
  40. ncbi Clinical potential of minocycline for neurodegenerative disorders
    David Blum
    Laboratory of Experimental Neurosurgery, ULB Erasme, 1070 Brussels, Belgium
    Neurobiol Dis 17:359-66. 2004
    ..In addition, we extend our discussion to the potential applications of minocycline for combining this treatment with cellular and molecular therapy...
  41. ncbi Minocycline in phenotypic models of Huntington's disease
    Kadiombo Bantubungi
    Laboratory of Neurophysiology, ULB-Erasme, Brussels, Belgium
    Neurobiol Dis 18:206-17. 2005
    ..Altogether, these data suggested that, in HD, minocycline may counteract the development of caspase-dependent neurodegeneration, inflammation, but not calpain-dependent neuronal death...
  42. ncbi The cerebellum modulates rodent cortical motor output after repetitive somatosensory stimulation
    Nordeyn Oulad Ben Taib
    Service de Neurochirurgie, Hôpital Erasme Université Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 56:811-20; discussion 811-20. 2005
    ..To analyze the possible role of the cerebellum in the modulation of cortical motor output associated with repetitive electrical stimulation of the sciatic nerve in the rat...
  43. ncbi Synovial cysts of the lumbar spine: surgery-related results and outcome
    Benoit Pirotte
    Department of Neurosurgery, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium
    J Neurosurg 99:14-9. 2003
    ..The authors conducted a study to determine the surgery-related results and outcomes in patients with synovial cysts of the lumbar spine. They emphasize several specific characteristics useful in clinical management...
  44. ncbi Performance of a new type of suction tip attachment during intramedullary tumor dissection: technical note
    Florence Lefranc
    Department of Neurosurgery, Erasme University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 61:E241; discussion E241. 2007
    ..V., Wijchen, The Netherlands). This tip is designed to be used during tumor resection to avoid surgical trauma to the spinal cord surrounding an intramedullary tumor and the associated blood vessels...
  45. ncbi Sterile surgical technique for shunt placement reduces the shunt infection rate in children: preliminary analysis of a prospective protocol in 115 consecutive procedures
    Benoit J M Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, 808 Route de Lennik, 1070 Brussels, Belgium
    Childs Nerv Syst 23:1251-61. 2007
    ..The objective of this study was to evaluate whether the rigid application of a sterile protocol for shunt placement was applicable on a routine basis and allowed the reduction of shunt infections (SI) in children...
  46. ncbi Combined cimetidine and temozolomide, compared with temozolomide alone: significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital, Belgium
    J Neurosurg 102:706-14. 2005
    ..CONCLUSIONS: Cimetidine, acting as an antiadhesive and therefore an antimigratory agent for glioma cells, could be added in complement to the cytotoxic temozolomide compound to combat both migrating and proliferating cells in GBM...
  47. ncbi Retractable self-expandable stent for endovascular treatment of wide-necked intracranial aneurysms: preliminary experience
    Boris Lubicz
    Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium
    Neurosurgery 58:451-7; discussion 451-7. 2006
    ..Recently, the first retractable self-expandable stent has been developed and we sought to evaluate the use of this stent for EVT of wide-necked intracranial aneurysms...
  48. ncbi Use of stereotactic PET images in dosimetry planning of radiosurgery for brain tumors: clinical experience and proposed classification
    Marc Levivier
    Department of Neurosurgery and Centre Gamma Knife, Hôpital Erasme and Université Libre de Bruxelles, Brussels, Belgium
    J Nucl Med 45:1146-54. 2004
    ..e., PET) and anatomic (i.e., MRI and CT) images for the radiosurgical treatment of brain tumors. We propose a classification describing the relative role of the information provided by PET in this multimodality image-guided approach...
  49. ncbi Facial nerve palsy in posterior fossa arachnoid cysts: report of two cases
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Belgium
    Childs Nerv Syst 21:587-90. 2005
    ..DISCUSSION: The relationships between the cyst and the facial nerve and between the facial nerve palsy and the size variation of the cyst are discussed and documented by pre- and postoperative magnetic resonance imaging...
  50. ncbi Characterization of gastrin-induced cytostatic effect on cell proliferation in experimental malignant gliomas
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital, Brussels, Belgium
    Neurosurgery 52:881-90; discussion 890-1. 2003
    ..CONCLUSION: Gastrin is able to significantly modify the growth levels of a number of experimental gliomas...
  51. ncbi Determination of RNA expression for cholecystokinin/gastrin receptors (CCKA, CCKB and CCKC) in human tumors of the central and peripheral nervous system
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital, Brussels, Belgium
    Int J Oncol 22:213-9. 2003
    ..This therefore suggests an important role for gastrin in the biological development of these tumors...
  52. ncbi Presidential guest lecture of the 32nd annual meeting of the International Society for the Study of the Lumbar Spine: highly sophisticated neurosurgery and the developing world. A permanent challenge
    Jacques Brotchi
    World Federation of Neurosurgical Societies, Department of Neurosurgery, Erasme Hospital, Brussels, Belgium
    Spine 31:1520-1. 2006
  53. ncbi Citicoline is not protective in experimental models of Huntington's disease
    Stephane Mievis
    IRIBHM, University of Brussels, ULB Erasme, Brussels, Belgium
    Neurobiol Aging 28:1944-6. 2007
    ..Altogether, our results suggest that citicoline is not a potential therapeutic agent for the treatment of Huntington's disease...
  54. ncbi Hemicerebellectomy blocks the enhancement of cortical motor output associated with repetitive somatosensory stimulation in the rat
    Nordeyn Oulad Ben Taib
    Service de Neurochirurgie, , Brussels, Belgium
    J Physiol 567:293-300. 2005
    ..Hemicerebellectomy blocked the enhancement of the corticomotor response. The cerebellum is a key player in this form of short-term plasticity...
  55. ncbi Detection of S100B, S100A6 and galectin-3 ligands in meningiomas as markers of aggressiveness
    Sabine Hancq
    Department of Neurosurgery, Erasmus University Hospital, Brussels, Belgium
    Int J Oncol 25:1233-40. 2004
    ..Our results thus suggest that the galectin-3-binding sites and S100B (and S100A6 to a lesser extent) could play a role in the aggressiveness characterizing atypical meningiomas...
  56. ncbi Gastrin significantly modifies the migratory abilities of experimental glioma cells
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital, Faculty of Medicine, , Brussels
    Lab Invest 82:1241-52. 2002
    ..These data all suggest that gastrin can act as an endogenous modulator of glioma progression...
  57. ncbi Minocycline-induced activation of tetracycline-responsive promoter
    Abdelwahed Chtarto
    Laboratory of Experimental Neurosurgery, CP602, U.L.B.-Erasme, Batiment C, Niveau 6, 808 Route de Lennik, 1070, Brussels, Belgium
    Neurosci Lett 352:155-8. 2003
    ....
  58. ncbi Characterization of the levels of expression of retinoic acid receptors, galectin-3, macrophage migration inhibiting factor, and p53 in 51 adamantinomatous craniopharyngiomas
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital and Laboratory of Histopathology, Faculty of Medicine, Free University of Brussels, Belgium
    J Neurosurg 98:145-53. 2003
    ....
  59. ncbi Granulocyte macrophage-colony stimulating factor gene transfer to induce a protective anti-tumoral immune response against the 9L rat gliosarcoma model
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Int J Oncol 20:1077-85. 2002
    ....
  60. ncbi Neurovascular compression anatomy and pain outcome in patients with classic trigeminal neuralgia treated by radiosurgery
    José G Lorenzoni
    Department of Neurosurgery, School of Medicine, Pontifica Universidad Catolica de Chile, Santiago, Chile
    Neurosurgery 62:368-75; discussion 375-6. 2008
    ..To study the influence of the anatomy of neurovascular compression (NVC) on pain outcome in patients with classic trigeminal neuralgia treated by radiosurgery...
  61. ncbi Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
    Florence Lefranc
    Laboratoire de Toxicologie, Institut de Pharmacie, , Campus de la Plaine, Blvd du Triomphe, 1050 Brussels, Belgium
    J Clin Oncol 23:2411-22. 2005
    ..Specific antimigratory compounds should be added to conventional radio- and/or chemotherapy...
  62. ncbi Characterization of gastrin-induced proangiogenic effects in vivo in orthotopic U373 experimental human glioblastomas and in vitro in human umbilical vein endothelial cells
    Florence Lefranc
    Department of Neurosurgery, Erasmus University Hospital
    Clin Cancer Res 10:8250-65. 2004
    ..This effect depends in part on the level of E-selectin activation, but not on IL-8 expression/release by HUVECs...
  63. ncbi Embolization of intradural vascular spinal cord tumors : report of five cases and review of the literature
    Georges Rodesch
    Service de Neuroradiologie Diagnostique et Therapeutique, Hopital Foch, 40 rue Worth, 92150, Suresnes, France
    Neuroradiology 50:145-51. 2008
    ..Embolization has been proposed as an approach that would facilitate VSCT resection...