Research Topics
| David A SackSummaryAffiliation: International Centre for Diarrhoeal Disease Research Country: Bangladesh Publications
| Collaborators
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Detail Information
Publications
Improved indicators of infant mortality for integrated primary healthcare programmesD A Sack
ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh
J Health Popul Nutr 18:61-8. 2000..S.A. The results of these examples demonstrate that the new indicators are more sensitive than traditional measures when describing infant mortality, and may better reflect the perception in infant mortality status in the community...- CholeraDavid A Sack
International Centre for Diarrhoeal Disease Research, Bangladesh, Centre for Health and Population Research, Dhaka, Bangladesh
Lancet 363:223-33. 2004..Appropriate case management has reduced deaths from diarrhoeal disease by an estimated 3 million per year compared with 20 years ago. Vaccination was thought to have no role for cholera, but new oral vaccines are showing great promise... - Randomised, double-blind, safety and efficacy of a killed oral vaccine for enterotoxigenic E. Coli diarrhoea of travellers to Guatemala and MexicoDavid A Sack
Vaccine Testing Unit, Johns Hopkins University, Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Vaccine 25:4392-400. 2007..We conclude that the new oral ETEC vaccine reduces the rate of more severe episodes of traveller's diarrhoea (TD) due to VPO-ETEC, but it did not reduce the overall rate of ETEC diarrhoea or of travellers' diarrhoea due to other causes... - A novel serovar of Shigella dysenteriae from patients with diarrhoea in BangladeshKaisar A Talukder
ICDDR, B Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
J Med Microbiol 56:654-8. 2007..coli serotype reference strains. It is therefore proposed that these isolates represent a new provisional serovar of S. dysenteriae, type strain KIVI 162... - Antibiotic resistance and genetic diversity of Shigella sonnei isolated from patients with diarrhoea between 1999 and 2003 in BangladeshKaisar A Talukder
ICDDR, B, Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
J Med Microbiol 55:1257-63. 2006..It can be concluded that endemic strains of Shigella sonnei isolated from patients in Bangladesh are diverse in their genetic pattern... - An improved technique for isolation of environmental Vibrio cholerae with epidemic potential: monitoring the emergence of a multiple-antibiotic-resistant epidemic strain in BangladeshShah M Faruque
Molecular Genetics Laboratory, Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Dhaka, Bangladesh
J Infect Dis 193:1029-36. 2006..cholerae occurs in the human host and leads to the start of an epidemic cycle dominated by a single clone of V. cholerae that spreads rapidly through environmental waters... - Pandemic strains of O3:K6 Vibrio parahaemolyticus in the aquatic environment of BangladeshM Sirajul Islam
International Centre for Diarrhoeal Disease Research, Bangladesh, GPO 128, Dhaka 1000, Bangladesh
Can J Microbiol 50:827-34. 2004..This is the first report on the isolation of pandemic O3:K6 strains of V. parahaemolyticus from the aquatic environment of Bangladesh... - Genetic diversity of El Tor strains of Vibrio cholerae O1 with hybrid traits isolated from Bangladesh and MozambiqueMohammad Ansaruzzaman
Laboratory Sciences Division, Centre for Health and Population Research, International Centre for Diarrhoeal Disease Research, Dhaka 1000, Bangladesh
Int J Med Microbiol 297:443-9. 2007.... - Characteristics of a pandemic clone of O3 : K6 and O4 : K68 Vibrio parahaemolyticus isolated in Beira, MozambiqueM Ansaruzzaman
ICDDR, B International Centre for Diarrhoeal Disease Research, Bangladesh, Mohakhali, Dhaka 1212, Bangladesh
J Med Microbiol 57:1502-7. 2008..The O3 : K58 (n=8), O4 : K13 (n=6), O3 : KUT (n=1) and O8 : K41 (n=1) strains showed unique characteristics different from the pandemic clone... - Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic areaShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
Proc Natl Acad Sci U S A 101:2123-8. 2004..cholerae strains and thus promotes the rare, multiple-gene transfer events needed to assemble the critical combination of genes required for pandemic spread... - Toxigenic Vibrio cholerae in the aquatic environment of Mathbaria, BangladeshMunirul Alam
International Center for Diarrhoeal Disease Research-Bangladesh, Dhaka, Bangladesh
Appl Environ Microbiol 72:2849-55. 2006..The biofilm community is concluded to be an additional reservoir of cholera bacteria in the aquatic environment between seasonal epidemics of cholera in Bangladesh... - Robust gut associated vaccine-specific antibody-secreting cell responses are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral killed bivalent V. cholerae O1/O139 whole cell cholera vaccine: comparison with other mucoSohel Shamsuzzaman
International Centre for Diarrhoeal Disease Research, Bangladesh, GPO Box 128, Dhaka 1000, Bangladesh
Vaccine 27:1386-92. 2009..This sets the ground for testing such vaccines in large field trials in Bangladesh and also demonstrates that addition of other vibrio components to the existing cholera vaccine does not alter the responses to the O1 vaccine components... - Seasonal cholera caused by Vibrio cholerae serogroups O1 and O139 in the coastal aquatic environment of BangladeshMunirul Alam
International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh
Appl Environ Microbiol 72:4096-104. 2006..cholerae O139 have been demonstrated. Based on the results of this study, the coastal ecosystem of the Bay of Bengal is concluded to be a significant reservoir for the epidemic serogroups of V. cholerae... - Diverse CTX phages among toxigenic Vibrio cholerae O1 and O139 strains isolated between 1994 and 2002 in an area where cholera is endemic in BangladeshSuraia Nusrin
Laboratory Sciences Division, ICDDR, B Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
J Clin Microbiol 42:5854-6. 2004.... - Surveillance of rotavirus in a rural diarrhoea treatment centre in Bangladesh, 2000-2006K Zaman
International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B, Mohakhali, Dhaka 1212, Bangladesh
Vaccine 27:F31-4. 2009..Rotavirus is an important cause of childhood diarrhoea in rural Bangladesh and this burden may be reduced with a rotavirus vaccination programme... - Genetic relatedness of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated in south AsiaKaisar A Talukder
Enteric Microbiology Laboratory, ICDDR, B Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
J Antimicrob Chemother 54:730-4. 2004..The aim of the present study was to determine the clonal relationships of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated from south Asia, and S. dysenteriae 1 strains associated with epidemics in 1978, 1984 and 1994... - Peru-15, a live attenuated oral cholera vaccine, is safe and immunogenic in Bangladeshi toddlers and infantsFirdausi Qadri
ICDDR, B Centre for Health and Population Research, Bangladesh
Vaccine 25:231-8. 2007..The responses to the reduced dose was lower. These studies demonstrate that Peru-15 at a dose of 2x10(8)cfu is safe and immunogenic in children in Bangladesh... - Genetic characteristics of Matlab variants of Vibrio cholerae O1 that are hybrids between classical and El Tor biotypesAshrafus Safa
Laboratory Sciences Division, Enteric Microbiology Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR, B, Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
J Med Microbiol 55:1563-9. 2006..The genetic relatedness of Matlab variants to the V. cholerae strains recently isolated in Mozambique is another important observation of this study, which underscores the epidemiological significance of Matlab variants... - Prevalence of virulence genes and cytolethal distending toxin production in Campylobacter jejuni isolates from diarrheal patients in BangladeshKaisar A Talukder
Enteric Microbiology Laboratory, Laboratory Sciences Division, ICDDR, B, GPO Box 128, Dhaka 1000, Bangladesh
J Clin Microbiol 46:1485-8. 2008..5%), cdtA (97.5%), cdtB (97.5%), cdtC (97.5%), and wlaN (7.5%) genes was detected in C. jejuni by PCR. All C. jejuni strains but one produced cytolethal distending toxin in a HeLa cell assay... - Temporal shifts in the dominance of serotypes of Shigella dysenteriae from 1999 to 2002 in Dhaka, BangladeshKaisar A Talukder
ICDDR, B Centre for Health and Population Research, Dhaka 1000, Bangladesh
J Clin Microbiol 41:5053-8. 2003..All the strains harboring the 140-MDa plasmid were positive for the ipaH gene, had Congo red binding abilities, and were positive by the Sereny test, demonstrating their invasive properties... - Characterization of a novel P[25],G11 human group a rotavirusMustafizur Rahman
ICDDR, B, Centre for Health and Population Research, Mohakhali, Dhaka-1212, Bangladesh
J Clin Microbiol 43:3208-12. 2005..This lack of high sequence similarity in the VP4 gene indicates that the Dhaka6 isolate represents a new group A rotavirus P genotype, to which we propose assignment of the designation P[25]... - Critical factors influencing the occurrence of Vibrio cholerae in the environment of BangladeshAnwar Huq
Center of Marine Biotechnology, University of Maryland Biotechnology Institute, 701 East Pratt Street, Baltimore, MD 21202, USA
Appl Environ Microbiol 71:4645-54. 2005..g., plankton population blooms. The new information on the ecology of V. cholerae is proving useful in developing environmental models for the prediction of cholera epidemics... - Transmissibility of cholera: in vivo-formed biofilms and their relationship to infectivity and persistence in the environmentShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
Proc Natl Acad Sci U S A 103:6350-5. 2006..The results of this study support a model of cholera transmission in which in vivo-formed biofilms contribute to enhanced infectivity and environmental persistence of pathogenic V. cholerae... - Cholera due to altered El Tor strains of Vibrio cholerae O1 in BangladeshG Balakrish Nair
Laboratory Sciences Division, ICDDR, B Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
J Clin Microbiol 44:4211-3. 2006..All of the El Tor strains of V. cholerae O1 isolated since 2001 produced CT of the classical biotype, while those isolated before 2001 produced CT of the El Tor biotype... - Prevalence of G2P[4] and G12P[6] rotavirus, BangladeshMustafizur Rahman
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
Emerg Infect Dis 13:18-24. 2007..1%) during this season. Because recently licensed rotavirus vaccines include only the P[8] specificity, it is unknown how the vaccines will perform in settings where non-P[8] types are prevalent... - Viable but nonculturable Vibrio cholerae O1 in biofilms in the aquatic environment and their role in cholera transmissionMunirul Alam
International Center for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
Proc Natl Acad Sci U S A 104:17801-6. 2007..cholerae cells freshly discharged into the environment are significantly less robust than cells adapted to environmental conditions... - Pathogenic potential of environmental Vibrio cholerae strains carrying genetic variants of the toxin-coregulated pilus pathogenicity islandShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
Infect Immun 71:1020-5. 2003..cholerae encode biologically active gene products. Detection of functional homologs of the TCP island genes in environmental strains may have implications for understanding the origin and evolution of virulence genes of V. cholerae... - New variants of Vibrio cholerae O1 biotype El Tor with attributes of the classical biotype from hospitalized patients with acute diarrhea in BangladeshG Balakrish Nair
Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
J Clin Microbiol 40:3296-9. 2002..Furthermore, the existence of such novel strains may have implications for the development of a cholera vaccine... - Shigella dysenteriae type 1-specific bacteriophage from environmental waters in BangladeshShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
Appl Environ Microbiol 69:7028-31. 2003..dysenteriae type 1 was isolated from three phage-positive samples. The results of this study suggest that phage SF-9 may have epidemiological applications in tracing the presence of S. dysenteriae type 1 in environmental waters... - Enterotoxigenic Escherichia coli and Vibrio cholerae diarrhea, Bangladesh, 2004Firdausi Qadri
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
Emerg Infect Dis 11:1104-7. 2005..ETEC that produced heat-stable enterotoxin alone was most prevalent, and 78% of strains had colonization factors. Like V. cholerae O1, ETEC can cause epidemic diarrhea... - Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in BangladeshFirdausi Qadri
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka
Infect Immun 73:6577-83. 2005..cholerae O139. Consequently, this assay may be useful in studies of both O139-infected patients and recipients of O139 vaccines... - Reemergence of epidemic Vibrio cholerae O139, BangladeshShah M Faruque
International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
Emerg Infect Dis 9:1116-22. 2003..These findings emphasize the need for continuous monitoring of the new epidemic strains... - Pandemic serovars (O3:K6 and O4:K68) of Vibrio parahaemolyticus associated with diarrhea in Mozambique: spread of the pandemic into the African continentM Ansaruzzaman
Laboratory Sciences Division, ICDDR, B Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
J Clin Microbiol 43:2559-62. 2005..This is the first report of the isolation of pandemic strains of V. parahaemolyticus in sub-Saharan Africa and clearly indicates that the pandemic of V. parahaemolyticus has spread into the African continent... - Reduced doses of oral killed enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine is safe and immunogenic in Bangladeshi infants 6-17 months of age: dosing studies in different age groupsFirdausi Qadri
International Centre for Diarrhoeal Disease Research, Bangladesh, GPO Box 128, Dhaka 1000, Bangladesh
Vaccine 24:1726-33. 2006..05-0.001). This study thus demonstrates that reduced doses of the ETEC vaccine is immunogenic in children and infants as well as safe in infants down to 6 months of age... - Isolation and characterization of provisional serovar Shigella boydii E16553 from diarrhoeal patients in BangladeshM Ansaruzzaman
International Center for Diarrhoeal Disease Research, Bangladesh, Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
J Med Microbiol 54:477-80. 2005..boydii 19... - Fluoroquinolone resistance linked to both gyrA and parC mutations in the quinolone resistance-determining region of Shigella dysenteriae type 1Kaisar A Talukder
ICDDR, B Centre for Health and Population Research, GPO Box 128, Dhaka, 1000, Bangladesh
Curr Microbiol 52:108-11. 2006..In fluoroquinolone-resistant strains, double mutations (Ser83-->Leu, Asp87-->Asn or Gly) and a single mutation (Ser80-->Ile) were detected in the QRDRs of gyrA and parC, respectively... - Effect of transport at ambient temperature on detection and isolation of Vibrio cholerae from environmental samplesMunirul Alam
International Center for Diarrhoeal Disease Research, Dhaka, Bangladesh
Appl Environ Microbiol 72:2185-90. 2006..cholerae from freshwater ecosystems can be achieved by holding samples at the ambient temperature, an observation that has significant implications for tracking this pathogen in diverse aquatic environments... - Surveillance for invasive Streptococcus pneumoniae disease among hospitalized children in Bangladesh: antimicrobial susceptibility and serotype distributionSamir K Saha
Department of Microbiology, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka, Bangladesh
Clin Infect Dis 48:S75-81. 2009..Vaccines offer the prospect of primary disease prevention of pneumococcal disease in childhood. For introduction of such vaccines in developing countries, information about disease epidemiology is necessary... - Detection and characterization of human group C rotaviruses in BangladeshMustafizur Rahman
ICDDR, B, Centre for Health and Population Research, Mohakhali, Dhaka, Bangladesh
J Clin Microbiol 43:4460-5. 2005..Phylogenetic analysis suggested that all human group C rotaviruses, including the strains isolated in our study, clustered in a monophyletic branch, which was distantly related to the branch comprised of animal group C rotaviruses... - Antigen-specific immunoglobulin A antibodies secreted from circulating B cells are an effective marker for recent local immune responses in patients with cholera: comparison to antibody-secreting cell responses and other immunological markersFirdausi Qadri
International Centre for Diarrhoeal Disease Research, Bangladesh, Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
Infect Immun 71:4808-14. 2003.... - CTXphi-independent production of the RS1 satellite phage by Vibrio choleraeShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
Proc Natl Acad Sci U S A 100:1280-5. 2003..cholerae strains. This study also shows that filamentous phages can package diverse DNA elements and thus may play a role in horizontal transfer of more genes than previously appreciated... - Seasonal epidemics of cholera inversely correlate with the prevalence of environmental cholera phagesShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka-1212, Bangladesh
Proc Natl Acad Sci U S A 102:1702-7. 2005..Our data support the conclusion that cholera phages can influence cholera seasonality and may also play a role in emergence of new V. cholerae pandemic serogroups or clones... - Reduction of cholera in Bangladeshi villages by simple filtrationRita R Colwell
Center of Marine Biotechnology, University of Maryland Biotechnology Institute, Baltimore, MD 21202, USA
Proc Natl Acad Sci U S A 100:1051-5. 2003..005) compared with the control... - Comparative safety and immunogenicity of two attenuated enterotoxigenic Escherichia coli vaccine strains in healthy adultsRobin McKenzie
Center for Immunization Research, Department of International Health, Johns Hopkins University, Bloomberg School of Public Health, 624 N Broadway, HH, Rm 203, Baltimore, MD 21205, USA
Infect Immun 74:994-1000. 2006..Based on its superior immunogenicity, which was comparable to that of a virulent ETEC strain and other ETEC vaccine candidates, PTL-003 will be developed further as a component of a live, oral attenuated ETEC vaccine... - Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: a randomised, double-blind, placebo-controlled trialK Zaman
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
Lancet 376:615-23. 2010..We assessed the clinical efficacy of live oral pentavalent rotavirus vaccine for prevention of severe rotavirus gastroenteritis in infants in Bangladesh and Vietnam... - Getting serious about choleraDavid A Sack
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
N Engl J Med 355:649-51. 2006 - Randomized, controlled study of the safety and immunogenicity of Peru-15, a live attenuated oral vaccine candidate for cholera, in adult volunteers in BangladeshFirdausi Qadri
International Centre for Diarrhoeal Disease Research, Bangladesh ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh
J Infect Dis 192:573-9. 2005..A lower immunological response against cholera toxin B subunit was detected.CONCLUSIONS. The safety and immunogenicity of this Peru-15 vaccine candidate indicates the usefulness of future studies in Bangladesh, where cholera is endemic... - Isolation of Shigella dysenteriae type 1 and S. flexneri strains from surface waters in Bangladesh: comparative molecular analysis of environmental Shigella isolates versus clinical strainsShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
Appl Environ Microbiol 68:3908-13. 2002.... - Refinement of a human challenge model for evaluation of enterotoxigenic Escherichia coli vaccinesClayton Harro
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Clin Vaccine Immunol 18:1719-27. 2011..After the second challenge, participants exhibited blunted anti-LPS and -LTB responses but a booster response to CFA/I. This ETEC model should prove useful in the future evaluation of ETEC vaccine candidates... - Safety and immunogenicity of an oral, inactivated enterotoxigenic Escherichia coli plus cholera toxin B subunit vaccine in Bangladeshi children 18-36 months of ageFirdausi Qadri
Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, GPO Box 128, Dhaka 1000, Bangladesh
Vaccine 21:2394-403. 2003..003 to <0.001). This study thus shows that the CF-BS-ETEC vaccine is well tolerated in children, 18-36 months of age and gives rise to significant systemic and mucosal IgA antibody responses... - Emergence and evolution of Vibrio cholerae O139Shah M Faruque
Laboratory Sciences Division, International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka-1212, Bangladesh
Proc Natl Acad Sci U S A 100:1304-9. 2003..cholerae, not only in the Ganges Delta region of India and Bangladesh, but also in other areas of endemic and epidemic cholera... - Typing of human rotaviruses: nucleotide mismatches between the VP7 gene and primer are associated with genotyping failureMustafizur Rahman
ICDDR, B Centre for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
Virol J 2:24. 2005..9%) of the rotavirus strains isolated in 2002 could not be G-typed using the routinely used primer set. To investigate the reason why the strains were untypeable, nucleotide sequencing of the VP7 genes was performed... - Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibioticRubhana Raqib
International Centre for Diarrhoeal Disease Research Bangladesh, Centre for Health and Population Research, Dhaka 1212, Bangladesh
Proc Natl Acad Sci U S A 103:9178-83. 2006.... - Zinc treatment for 5 or 10 days is equally efficacious in preventing diarrhea in the subsequent 3 months among Bangladeshi childrenDewan S Alam
Health Systems and Infectious Diseases Division, International Centre for Diarrheal Disease Research, Bangladesh, Mohakhali, Dhaka, Bangladesh
J Nutr 141:312-5. 2011..These findings suggest that among Bangladeshi children, a 5-d zinc treatment for ACD is as efficacious as 10 d in preventing diarrhea in the subsequent 3 mo... - Volunteer challenge with enterotoxigenic Escherichia coli that express intestinal colonization factor fimbriae CS17 and CS19Robin McKenzie
Department of Medicine, Johns Hopkins University, Johns Hopkins Bayview Medical Center, MD, USA
J Infect Dis 204:60-4. 2011..These studies establish the relative pathogenicity of ETEC expressing newer class 5 fimbriae and suggest suitability of the LT|CS17-ETEC challenge model for interventional trials... - Global dissemination of Vibrio parahaemolyticus serotype O3:K6 and its serovariantsG Balakrish Nair
Enteric Microbiology Unit, Laboratory Sciences Division, ICDDR, B Center for Health and Population Research, Mohakhali, Dhaka 1212, Bangladesh
Clin Microbiol Rev 20:39-48. 2007..This review traces the genesis, virulence features, molecular characteristics, serotype variants, environmental occurrence, and global spread of this unique clone of V. parahaemolyticus... - Achieving the millennium development goals for health and nutrition in Bangladesh: key issues and interventions--an introductionDavid A Sack
Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street/E5036, Baltimore, Maryland 21205, USA
J Health Popul Nutr 26:253-60. 2008 - Antidiarrheal effects of L-histidine-supplemented rice-based oral rehydration solution in the treatment of male adults with severe cholera in Bangladesh: a double-blind, randomized trialGolam H Rabbani
Clinical Sciences Division, Centre for Health and Population Research, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
J Infect Dis 191:1507-14. 2005..Because of the antisecretory potential of L-histidine in the intestinal tract, its antidiarrheal effects were determined in cholera... - Symptomatic hyponatremia during treatment of dehydrating diarrheal disease with reduced osmolarity oral rehydration solutionNur H Alam
Clinical Sciences Division, International Centre for Diarrhoeal Disease Research Bangladesh, Mohakhali, Dhaka, Bangladesh
JAMA 296:567-73. 2006.... - Diarrhoea in elderly people: aetiology, and clinical characteristicsAbu S G Faruque
From the Clinical Sciences Division, ICDDR, B Centre for Health and Population Research, GPO Box 128, Dhaka 1000, Bangladesh
Scand J Infect Dis 36:204-8. 2004..Early initiation of oral or i.v. rehydration therapy, prompt referral, and immediate clinical diagnosis for assessment of the need for antibiotic therapy might be beneficial for the elderly... - Nutrition: basis for healthy children and mothers in BangladeshA S G Faruque
Clinical Sciences Division, ICDDR, B, GPO Box 128, Dhaka 1000, Mohakhali, Bangladesh
J Health Popul Nutr 26:325-39. 2008.... - Rotavirus-specific subclass antibody and cytokine responses in Bangladeshi children with rotavirus diarrhoeaTasnim Azim
ICDDR, B Centre for Health and Population Research, Dhaka, Bangladesh
J Med Virol 69:286-95. 2003..The immune responses described are relevant to future vaccine trials, as immune responses in vaccinees should mimic those in natural infection... - A 4-year study of the epidemiology of Vibrio cholerae in four rural areas of BangladeshR Bradley Sack
Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
J Infect Dis 187:96-101. 2003..These data will be correlated with environmental factors, to develop a model for prediction of cholera outbreaks... - Prevalence of the pandemic genotype of Vibrio parahaemolyticus in Dhaka, Bangladesh, and significance of its distribution across different serotypesN A Bhuiyan
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka-1212, Bangladesh
J Clin Microbiol 40:284-6. 2002..A marker (open reading frame ORF8) for a filamentous phage previously thought to correspond to the pandemic genotype was found to have a poor correlation with the pandemic genotype... - Use of antibodies in lymphocyte secretions for detection of subclinical tuberculosis infection in asymptomatic contactsRubhana Raqib
ICDDR, B Centre for Health and Population Research, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh
Clin Diagn Lab Immunol 11:1022-7. 2004..The method may also allow discrimination between effective treatment of active infection and suboptimal response to therapy... - Phenotypic and genotypic characterization of serologically atypical strains of Shigella flexneri type 4 isolated in Dhaka, BangladeshKaisar A Talukder
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1000, Bangladesh
J Clin Microbiol 40:2490-7. 2002..This study concluded that two different clones of atypical S. flexneri type 4 exist and strongly suggests that these are new subserotypes of S. flexneri that await further serological classification... - Self-limiting nature of seasonal cholera epidemics: Role of host-mediated amplification of phageShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research Bangladesh, Dhaka 1212, Bangladesh
Proc Natl Acad Sci U S A 102:6119-24. 2005..cholerae and, hence, the collapse of the epidemic. Thus, in vivo phage amplification in patients and subsequent phage predation in the environment may explain the self-limiting nature of seasonal cholera epidemics in Bangladesh... - Invasive pneumococcal disease burden and implications for vaccine policy in urban BangladeshW Abdullah Brooks
ICDDR, B, Mohakhali, Dhaka, Bangladesh
Am J Trop Med Hyg 77:795-801. 2007..9%, 82.4%, 14.7%, and 24.1%, respectively. Current conjugate vaccines should substantially reduce IPD, childhood pneumonia, and antimicrobial resistance in Bangladesh... - RS1 element of Vibrio cholerae can propagate horizontally as a filamentous phage exploiting the morphogenesis genes of CTXphiShah M Faruque
Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka 1212, Bangladesh
Infect Immun 70:163-70. 2002..The results of this study showed for the first time that RS1 element, which encodes a site-specific recombination system in V. cholerae, can propagate horizontally as a filamentous phage, exploiting the morphogenesis genes of CTXPhi... - Phenotypic and genotypic characterization of provisional serotype Shigella flexneri 1c and clonal relationships with 1a and 1b strains isolated in BangladeshKaisar A Talukder
Enteric Laboratory, Laboratory Sciences Division, International Centre for Diarrhoeal Diseases Research, Bangladesh
J Clin Microbiol 41:110-7. 2003..Furthermore, the high rate of prevalence of serotype 1c necessitates the commercial production of antibody against this subserotype to allow the determination of the actual burden of shigellosis caused by provisional serotype 1c... - Mapping hypoendemic, seasonal malaria in rural Bandarban, Bangladesh: a prospective surveillanceWasif A Khan
ICDDR, B International Centre for Diarrhoeal Disease Research, Clinical Sciences Division
Malar J 10:124. 2011.... - Rapid diagnosis of active tuberculosis by detecting antibodies from lymphocyte secretionsRubhana Raqib
International Center for Diarrhoeal Disease Research, Bangladesh
J Infect Dis 188:364-70. 2003..Patients with active TB had higher BCG- or PPD-specific IgG antibody responses than patients without TB or healthy subjects (P=.001). This method can be used as a quick diagnostic aid to facilitate rapid detection of TB cases... - Adaptive and inflammatory immune responses in patients infected with strains of Vibrio parahaemolyticusFirdausi Qadri
International Centre for Diarrhoeal Disease Research, Bangladesh, GPOBox 128, Dhaka 1000, Bangladesh
J Infect Dis 187:1085-96. 2003..Infection with V. parahaemolyticus results in B cell responses and an acute inflammatory response that is self-limiting... - Impending concentrated HIV epidemic among injecting drug users in Central BangladeshTasnim Azim
Int J STD AIDS 15:280-2. 2004 - Enteroaggregative Escherichia coli diarrhea in travelers: response to rifaximin therapyRosa M Infante
Center for Infectious Diseases, The University of Texas-Houston School of Public Health and Medical School, Houston, Texas, USA
Clin Gastroenterol Hepatol 2:135-8. 2004..The study provides information on the value of the poorly absorbed drug rifaximin in therapy of travelers' diarrhea... - When should cholera vaccine be used in cholera-endemic areas?David A Sack
J Health Popul Nutr 21:299-303. 2003 - An unusual cluster of dysentery due to Shigella dysenteriae type 4 in Dhaka, BangladeshKaisar A Talukder
J Med Microbiol 54:511-3. 2005 - The effect of rainfall on the incidence of cholera in BangladeshMasahiro Hashizume
Public and Environmental Health Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
Epidemiology 19:103-10. 2008..The incidence of cholera in Bangladesh shows clear seasonality, suggesting that weather factors could play a role in its epidemiology. We estimated the effects of rainfall on the incidence of cholera in Dhaka, Bangladesh... - Emergence of multidrug-resistant strain of Vibrio cholerae O1 in Bangladesh and reversal of their susceptibility to tetracycline after two yearsAbu S G Faruque
J Health Popul Nutr 25:241-3. 2007 - Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysisMohammad Ali
International Vaccine Institute, Seoul, Korea
Lancet 366:44-9. 2005..Use of these vaccines could have a major effect on the burden of cholera in endemic settings... - Multilocus sequence typing (MLST) analysis of Vibrio cholerae O1 El Tor isolates from Mozambique that harbour the classical CTX prophageJe Hee Lee
International Vaccine Institute, San 4-8 Bongcheon 7 dong, Kwanak gu, Seoul, 151-818, Republic of Korea
J Med Microbiol 55:165-70. 2006..The possible origin of these isolates and the presence of the tandem repeat of the classical prophage in them implicate the presence of the classical CTX phage... - Efficacy calculation in randomized trials: global or local measures?Michael Emch
Department of Geography, Saunders Hall, University of North Carolina, Chapel Hill, NC 27599 3220 USA
Health Place 13:238-48. 2007..Local efficacy measures can help public health practitioners make better decisions about when and where to vaccinate populations. The concepts offered in this study are pertinent for any health intervention trial, not just vaccines... - Therapy of travelers' diarrhea with rifaximin on various continentsRobert Steffen
Division of Communicable Diseases, Institute of Social and Preventive Medicine of the University, Zurich, Switzerland
Am J Gastroenterol 98:1073-8. 2003..No relevant side effects were reported. CONCLUSION: Rifaximin is efficacious and safe for treatment of travelers' diarrhea at daily doses of 600 mg or higher... - Relationship between neighbourhood-level killed oral cholera vaccine coverage and protective efficacy: evidence for herd immunityMichael Emch
Department of Geography, Saunders Hall, Campus Box 3220, University of North Carolina Chapel Hill, 27599 3220, USA
Int J Epidemiol 35:1044-50. 2006.... - O3:K6 serotype of Vibrio parahaemolyticus identical to the global pandemic clone associated with diarrhea in PeruAna I Gil
Instituto de Investigacion Nutricional, Av La Molina 1885, Lima 12, Peru, AP 18 091, Lima 18, Peru
Int J Infect Dis 11:324-8. 2007..To determine if the Vibrio parahaemolyticus O3:K6 global pandemic clone has spread into Peru...