Effects of melatonin supplementation on exercise-induced changes in conduction velocity distributionsM Ayaz
Department of Biophysics, Meram Medical Faculty, Selcuk University, Meram, Konya, Turkey
Methods Find Exp Clin Pharmacol 31:151-6. 2009
..Presupplementation not only protects the nerve cells from exercise-induced damage, but also increases the contribution of nerve fibers with conduction velocities of 46-52 m/s...
- Electrophysiology of papillary muscle in SAH: changes and N-acetylcysteine protection
Murat Ayaz
Selcuk University, Meram Medical Faculty, Department of Biophysics, 42080, Meram, Konya, Turkey
J Interv Card Electrophysiol 26:95-100. 2009
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- Coenzyme Q(10) and alpha-lipoic acid supplementation in diabetic rats: conduction velocity distributions
Murat Ayaz
Department of Biophysics, Selcuk University, Meram Medical Faculty, Meram, Konya, Turkey
Methods Find Exp Clin Pharmacol 30:367-74. 2008
..In addition to its effects on mitochondrial alterations, these positive effects of CoQ10 on diabetic neuropathy can be attributed to its antioxidant activity...
- Selenium-induced changes on rat sciatic nerve fibers: compound action potentials
Murat Ayaz
Department of Biophysics, Meram Medical Faculty Selcuk University, Konya, Turkey
Methods Find Exp Clin Pharmacol 30:271-5. 2008
..Despite the fact that the new claims concluded the positive effects of the administrations, it is evident that the dose of supplementation must be fine-tuned to avoid possible side effects...
- Sexual dependency of rat sciatic nerve fiber conduction velocity distributions
Murat Ayaz
Department of Biophysics, Selcuk University Meram Medical Faculty, Konya, Turkey
Int J Neurosci 117:1537-49. 2007
..The present study, for the first time clearly shows that shift in the contribution of nerve fibers to lower CVs is the main causal of the sex dependent differences seen in rat sciatic nerve fibers...
- Plasma and erythrocytes antioxidant status and trace element levels in proteinuric patients with moderate glomerular function
D Konukoglu
Department of Biochemistry, University of Istanbul, Cerrahpasa Medical Faculty, Turkey
J Trace Elem Med Biol 15:119-22. 2001
..This study was concluded that cellular antioxidant activity decreases in proteinuric patients with moderate glomerular function. This may increase lipid peroxidation reactions by causing oxidative stress in erythrocyte membranes...
- Selenium-induced alterations in ionic currents of rat cardiomyocytes
Murat Ayaz
Department of Biophysics, School of Medicine, Ankara University, 06100 Ankara, Turkey
Biochem Biophys Res Commun 327:163-73. 2005
..These alterations, in the kinetics of the channels and in IK1 density, might lead to proarrhythmic effect of chronic selenium supplementation...
- Effects of selenium on altered mechanical and electrical cardiac activities of diabetic rat
Murat Ayaz
Department of Biophysics, Faculty of Medicine, Ankara University, 06100 Ankara, Turkey
Arch Biochem Biophys 426:83-90. 2004
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- Protective effect of selenium treatment on diabetes-induced myocardial structural alterations
Murat Ayaz
Department of Biophysics, Faculty of Medicine, Ankara University, 06100, Ankara, Turkey
Biol Trace Elem Res 89:215-26. 2002
..Under these findings, one can suggest that sodium selenite treatment may alleviate late diabetic complications when it is used under control conditions...
- Bupivacaine and ropivacaine: comparative effects on nerve conduction block
H Bariskaner
Selcuk University Meram Medical Faculty, Department of Pharmacology, 42080 Akyokus Meram Konya, Turkey
Methods Find Exp Clin Pharmacol 29:337-41. 2007
..In conclusion, ropivacaine has a sensory specific side of action, when compared with the bupivacaine...
- Vegetable oils used as vitamin E vehicle affect the electrical activity of the rat heart
S Ozdemir
Department of Biophysics, Faculty of Medicine, Ankara University, Turkey
Physiol Res 52:767-71. 2003
..The present data indicate that the possible effect of vegetable oil vehicles should be kept in mind while evaluating the possible effects of in vivo vitamin E administration...
- Toxic concentrations of selenite shortens repolarization phase of action potential in rat papillary muscle
Mehmet Ugur
Department of Biophysics, Faculty of Medicine, Ankara University, 06100, Ankara, Turkey
Biol Trace Elem Res 89:227-38. 2002
..Our findings also suggest that a decrease in Na+ currents, in addition to Ca2+ currents, may play a role in the shortening of AP duration in rat papillary muscles...
- Selenium prevents diabetes-induced alterations in [Zn2+]i and metallothionein level of rat heart via restoration of cell redox cycle
Murat Ayaz
Department of Biophysics, School of Medicine, Ankara University, Sihhiye, 06100, Ankara, Turkey
Am J Physiol Heart Circ Physiol 290:H1071-80. 2006
..In addition, we showed that oxidative stress is involved in the etiology of diabetes-induced downregulation of heart function via depressed endogenous antioxidant defense mechanisms...
- Effect of selenite treatment on ultrastructural changes in experimental diabetic rat bones
Semir Ozdemir
Department of Biophysics, School of Medicine, Ankara University, Turkey
Biol Trace Elem Res 107:167-79. 2005
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- Sodium selenite protects against diabetes-induced alterations in the antioxidant defense system of the liver
Murat Ayaz
Department of Biophysics, Meram Medical Faculty, Selcuk University, 42080 Konya, Turkey
Diabetes Metab Res Rev 22:295-9. 2006
..In this study, the effects of micro molar quantities of sodium selenite treatment on diabetes-induced alterations in the antioxidant defense system were investigated...
- Gender-dependent effects of selenite on the perfused rat heart: a toxicological study
Murat Ayaz
Department of Biophysics, Meram Medical Faculty, Selcuk University, 42080 Konya, Turkey
Biol Trace Elem Res 116:301-10. 2007
..This modification is more pronounced in the contraction cascade of female rats. Males, on the other hand, had been much more affected in excitation-related parameters...
- Resveratrol-induced depression of the mechanical and electrical activities of the rat heart is reversed by glyburide: evidence for possible K(ATP) channels activation
Mesut Buluc
Department of Pharmacology and Clinical Pharmacology, Ankara University, Faculty of Medicine, Sihhiye, 06100 Ankara, Turkey
Arch Pharm Res 30:603-7. 2007
..These results indicated that resveratrol depressed cardiac muscle contraction and shortened action potential duration probably due to the activation of K(ATP) channels in the rat heart...
