Research Topics
Species | S StadlmannSummaryAffiliation: University of Innsbruck Country: Austria Publications
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Detail Information
Publications
Ovarian carcinoma cells and IL-1beta-activated human peritoneal mesothelial cells are possible sources of vascular endothelial growth factor in inflammatory and malignant peritoneal effusionsSylvia Stadlmann
Department of Pathological Anatomy, Innsbruck Medical University, A 6020 Innsbruck, Austria
Gynecol Oncol 97:784-9. 2005..We compared the VEGF secretion by human peritoneal mesothelial cells (HPMC) and ovarian carcinoma (OVCA) cells and its regulation by pro-inflammatory cytokines...
Heparanase-1 gene expression in normal, hyperplastic and neoplastic prostatic tissueS Stadlmann
Institute of Pathology, University of Innsbruck, Muellerstrasse 44, 6020 Innsbruck, Austria
Eur J Cancer 39:2229-33. 2003..Hpa-1 mRNA expression in the tumours significantly correlated with tumour differentiation and tumour stage (P<0.05). Our data indicate that Hpa-1 gene expression may be lost during dedifferentiation of prostatic gland cells...
Cytokine-regulated expression of collagenase-2 (MMP-8) is involved in the progression of ovarian cancerS Stadlmann
Institute of Pathology, University of Innsbruck, Muellerstrasse 44, 6020 Innsbruck, Austria
Eur J Cancer 39:2499-505. 2003..01). The data indicate that MMP-8 overexpression in OVCAs is regulated by IL-1beta and that pro-inflammatory cytokines may promote the invasive potential of ovarian cancer...
Mitochondrial defects by intracellular calcium overload versus endothelial cold ischemia/reperfusion injuryE Gnaiger
Department of Transplant Surgery, University Hospital Innsbruck, Austria
Transpl Int 13:S555-7. 2000..In contrast, Ca2+ overload caused uncoupling of mitochondrial respiration. High intracellular Ca2+ overload, therefore, does not reproduce cold ischemia/reperfusion injury in endothelial cells...
Primary iron overload with inappropriate hepcidin expression in V162del ferroportin diseaseHeinz Zoller
Clinical Division of Gastroenterology and Hepatology, Innsbruck Medical University, Innsbruck, Austria
Hepatology 42:466-72. 2005..Finally, macrophage iron storage in ferroportin disease is associated with elevated serum pro-hepcidin levels...
Herbal hepatotoxicity: acute hepatitis caused by a Noni preparation (Morinda citrifolia)Gunda Millonig
Clinical Division of Gastroenterology and Hepatology, Medical University of Innsbruck, Austria
Eur J Gastroenterol Hepatol 17:445-7. 2005..To our knowledge, this is the first report of hepatotoxicity caused by this herbal remedy, which has been highly praised in the tabloid press...
A cost comparison of telepathology and a visiting pathologist servicePatrizia L Moser
Department of Pathology, University of Innsbruck, Austria
J Telemed Telecare 9:200-3. 2003..The present case-load (eight cases per month) at the study hospital was below this threshold...
The accuracy of telediagnosis of frozen sections is inferior to that of conventional diagnosis of frozen sections and paraffin-embedded sectionsPatrizia L Moser
Department of Pathology, University of Innsbruck, Austria
J Telemed Telecare 9:130-4. 2003....
Ciprofloxacin-induced acute liver injury: case report and review of literatureAnnette Zimpfer
Institute of Pathology, University of Basel, Schoenbeinstrasse 40, 4003 Basel, Switzerland
Virchows Arch 444:87-9. 2004..Symptoms resolved after corticoidsteroid therapy. In the present paper, we report the clinico-pathological characteristics of a case of ciprofloxacin-associated acute hepatic failure and discuss the current literature...
ERCC1-immunoexpression does not predict platinum-resistance in ovarian cancerSylvia Stadlmann
Gynecol Oncol 108:252-3. 2008
Glypican-3 expression in primary and recurrent ovarian carcinomasSylvia Stadlmann
Institute of Pathology, University Hospital Basel, Basel, Switzerland
Int J Gynecol Pathol 26:341-4. 2007..In conclusion, our data show that GPC3 is observed in a significant fraction of primary and corresponding recurrent ovarian carcinomas. Glypican-3 may therefore represent a potential target for (second-line) therapy in ovarian cancer...
Clinical relevance of E2F family members in ovarian cancer--an evaluation in a training set of 77 patientsDaniel Reimer
Department of Obstetrics and Gynecology, Innsbruck Medical University, Innsbruck, Austria
Clin Cancer Res 13:144-51. 2007..We therefore investigated the relevance of the whole set of E2F family members in predicting clinical outcome and their significance in predicting platinum resistance...
Fatal liver failure in an adult patient with acute lymphoblastic leukemia following treatment with L-asparaginaseMichael Bodmer
Division of Clinical Pharmacology and Toxicology, University Hospital, Basel, Switzerland
Digestion 74:28-32. 2006..Both impaired liver mitochondrial function and alterations in very-low-density lipoprotein metabolism and secretion are discussed as two possible mechanisms explaining the findings observed in this patient...
Clinico-histopathological characteristics of clopidogrel-induced hepatic injury: case report and review of literatureIsolde Höllmüller
Department of Gastroenterology and Hepatology, Innsbruck Medical University, Austria
Eur J Gastroenterol Hepatol 18:931-4. 2006..In the present paper, we describe the clinico-histopathological characteristics of a case of clopidogrel-induced acute hepatitis and discuss the current literature...
Expression of peroxisome proliferator activated receptor gamma and cyclo-oxygenase 2 in primary and recurrent ovarian carcinomaSylvia Stadlmann
Institute of Pathology, University Hospital Basel, Basel, Switzerland
J Clin Pathol 60:307-10. 2007..Peroxisome proliferator-activated receptor gamma (PPARgamma) has emerged as a potential therapeutic target in several types of cancer. In ovarian carcinomas, limited and conflicting data on PPARgamma protein expression have been reported...
Response of human peritoneal mesothelial cells to inflammatory injury is regulated by interleukin-1beta and tumor necrosis factor-alphaSylvia Stadlmann
Institute of Pathology, University of Basel, Basel, Switzerland
Wound Repair Regen 14:187-94. 2006..Our data indicate that the response of HPMC to inflammatory injury is regulated by interleukin-1beta and TNF-alpha reflecting their putative role in peritoneal wound healing and adhesion formation...
Epithelial growth factor receptor status in primary and recurrent ovarian cancerSylvia Stadlmann
Institute for Pathology, University Hospital of Basel, Basel, Switzerland
Mod Pathol 19:607-10. 2006..003). In recurrent carcinoma, moderate and strong EGFR expression was associated with amplification (P = 0.034). These molecular events potentially have impact on the responsiveness to EGFR targeting agents in ovarian cancer...
Preserved coupling of oxidative phosphorylation but decreased mitochondrial respiratory capacity in IL-1beta-treated human peritoneal mesothelial cellsSylvia Stadlmann
Department of Pathological Anatomy, University Hospital Innsbruck, Austria
Cell Biochem Biophys 44:179-86. 2006....
Disruption of the integrity of human peritoneal mesothelium by interleukin-1beta and tumor necrosis factor-alphaSylvia Stadlmann
Institute of Pathology, University of Innsbruck, 6020, Innsbruck, Austria
Virchows Arch 443:678-85. 2003....
14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patientsAlexander Perathoner
Tyrolean Cancer Research Institute, Innsbruck, Austria
Clin Cancer Res 11:3274-9. 2005..In this study, we examined the expression of 14-3-3sigma and evaluated its clinical significance in colorectal carcinoma...
Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a tissue microarray analysis of 4,387 tissue samplesDaniel Baumhoer
Institute of Pathology, University Hospital Basel, Basel, Switzerland
Am J Clin Pathol 129:899-906. 2008..Furthermore, several other tumors revealed consistent expression of GPC3, including squamous cell carcinoma of the lung (27/50 [54%]), testicular nonseminomatous germ cell tumors (32/62 [52%]), and liposarcoma (15/29 [52%])...
