Research Topics
Genomes and Genes
| Siegfried ReipertSummaryAffiliation: University of Vienna Country: Austria Publications
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Detail Information
Publications
Tubulohelical membrane arrays: From the initial observation to the elucidation of nanophysical properties and cellular functionSiegfried Reipert
Department of Biochemistry and Cell Biology, Max F, Perutz Laboratories, University of Vienna, Dr, Bohrgasse 9, A 1030 Vienna, Austria
PMC Biophys 3:13. 2010..Finally, we raise the question of whether putative nanooptical properties of TUHMAs could serve for communicating orientation between dividing cells.MCS codes: 92C37, 92C05, 92C50...
Tubulohelical membrane arrays: novel association of helical structures with intracellular membranesSiegfried Reipert
Department of Molecular Cell Biology, Max F Perutz Laboratories, Dr Bohr Gasse 9, University of Vienna, A 1030 Vienna, Austria
Cell Biol Int 33:217-23. 2009..This should make TUHMAs more easily accessible for future studies on their structure and function...
Microtubule-tethering junctions are fine structural distinct entities that deserve attentionSiegfried Reipert
Department of Molecular Cell Biology, Max F Perutz Laboratories, University of Vienna, Dr Bohr Gasse 9, A 1030 Vienna, Austria
Traffic 8:1706-7. 2007..Here, we encourage systematic analysis of cortical microtubule capture by electron microscopy...
Rapid microwave fixation of cell monolayers preserves microtubule-associated cell structuresSiegfried Reipert
Department of Molecular Cell Biology, Max F Perutz Laboratories, Dr Bohr Gasse 9, University of Vienna, A 1030 Vienna, Austria
J Histochem Cytochem 56:697-709. 2008..To establish a valuable routine program for fine structural studies of resin-embedded cell models on substrata, a protocol combining MW fixation with automatic processing in a tissue processor is provided...
Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoformsPatryk Konieczny
Max F Perutz Laboratories, Department of Molecular Cell Biology, University of Vienna, A 1030 Vienna, Austria
J Cell Biol 181:667-81. 2008..Our findings establish plectin as the major organizer of desmin IFs in myofibers and provide new insights into plectin- and desmin-related muscular dystrophies...
Pun1p is a metal ion-inducible, calcineurin/Crz1p-regulated plasma membrane protein required for cell wall integrityDagmar Hosiner
Department of Microbiology, Immunobiology and Genetics, University of Vienna, A 1030 Vienna, Austria
Biochim Biophys Acta 1808:1108-19. 2011..We propose that Pun1p is a stress-regulated factor required for cell wall integrity, thereby expanding the functional significance of lateral plasma membrane compartments...
Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocityPeter Fuchs
Department of Biochemistry and Cell Biology, Max F Perutz Laboratories, University of Vienna, 1030 Vienna, Austria
J Biol Chem 284:26502-9. 2009..This is the first report demonstrating an important role of plectin in a major nerve function...
Novel components of an active mitochondrial K(+)/H(+) exchangeLudmila Zotova
Department of Microbiology, Max F Perutz Laboratories, Vienna University, A 1030 Vienna, Austria
J Biol Chem 285:14399-414. 2010..Based on these results, we propose that Ydl183p and the Mdm38p homologues Mrs7p, LETM1, and HCCR-1 are involved in the formation of an active KHE system...
Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-OgnaGernot Walko
Department of Biochemistry and Cell Biology, Max F Perutz Laboratories, Centre for Molecular Biology, University of Vienna, Vienna, Austria
PLoS Genet 7:e1002396. 2011..We propose focal self-association of plectin molecules as a novel mechanism contributing to hemidesmosome homeostasis and stabilization...
Unique membrane-interacting properties of the immunostimulatory cationic peptide KLKL(5)KLK (KLK)Michael C Aichinger
Department of Genetics, Max F Perutz Laboratories, Vienna, Austria
Cell Biol Int 32:1449-58. 2008..Our results suggest a profound membrane interacting property of KLK that might contribute to the immunostimulatory activities of IC31...
Plectin-controlled keratin cytoarchitecture affects MAP kinases involved in cellular stress response and migrationSelma Osmanagic-Myers
Department of Molecular Cell Biology, Max F Perutz Laboratories, University of Vienna, A 1030 Vienna, Austria
J Cell Biol 174:557-68. 2006..These data establish a link between cytolinker-controlled cytoarchitecture/scaffolding functions of keratin IFs and specific MAP kinase cascades mediating distinct cellular responses...
High-pressure freezing and low-temperature fixation of cell monolayers grown on sapphire coverslipsSiegfried Reipert
Department of Molecular Cell Biology, Max F. Perutz Laboratories, University of Vienna, Dr. Bohr-Gasse 9, A-1030 Vienna, Austria
Methods Cell Biol 88:165-80. 2008
Epiplakin is dispensable for skin barrier function and for integrity of keratin network cytoarchitecture in simple and stratified epitheliaDaniel Spazierer
Department of Molecular Cell Biology, Max F Perutz Laboratories, University of Vienna, Dr Bohrgasse 9, A 1030 Vienna, Austria
Mol Cell Biol 26:559-68. 2006....
A carboxysomal carbon-concentrating mechanism in the cyanelles of the 'coelacanth' of the algal world, Cyanophora paradoxa?Sara Fathinejad
Max F Perutz Laboratories, University Departments at the Vienna Biocenter, Department of Biochemistry, 1030 Vienna, Austria
Physiol Plant 133:27-32. 2008..A final decision between carboxysome or pyrenoid must await the identification of cyanelle carbonic anhydrase and, especially, the demonstration of shell proteins...
Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycanGünther A Rezniczek
Max F Perutz Laboratories, Department of Molecular Cell Biology, University of Vienna, A 1030 Vienna, Austria
J Cell Biol 176:965-77. 2007..It also explains the plectin phenotype observed in dystrophic skeletal muscle of mdx mice and Duchenne muscular dystrophy patients...
High-pressure cryoimmobilization of murine skin reveals novel structural features and prevents extraction artifactsSiegfried Reipert
Institute of Biochemistry and Molecular Cell Biology, Vienna Biocenter, University of Vienna, Dr Bohrgasse 9, 1030 Vienna, Austria
Exp Dermatol 13:419-25. 2004..Taken together, HPF in combination with freeze substitution emerges as a highly sensitive tool for morphological and ultrastructural analysis...
Stimulation of inducible nitric oxide synthase expression by beta interferon increases necrotic death of macrophages upon Listeria monocytogenes infectionHeather Zwaferink
Max F Perutz Laboratories, Department of Microbiology and Immunobiology, University of Vienna, Dr Bohr Gasse 9 4, A1030 Vienna, Austria
Infect Immun 76:1649-56. 2008..Based on morphology, the maintenance of mitochondrial membrane potential, and a lack of dependence on caspase 1, we characterize the type of cell death occurring and show that infected macrophages die by interferon-upregulated necrosis...
The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndromeKarin Nowikovsky
Max F Perutz Laboratories, Departments of Microbiology and Genetics, University of Vienna, Campus Vienna Biocenter, A 1030 Vienna, Austria
J Biol Chem 279:30307-15. 2004..Thus, YOL027/LETM1 are the first genes shown to encode factors involved in both K+ homeostasis and organelle volume control...
LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type laminsAndreas Brachner
Department of Medical Biochemistry, Max F Perutz Laboratories, Vienna Biocenter, Medical University of Vienna, Dr Bohrgasse 9 3, A 1030 Vienna, Austria
J Cell Sci 118:5797-810. 2005..LEM2 structures recruit A-type lamins, emerin, MAN1 and BAF, whereas lamin B and lamin B receptor are excluded. Our data identify LEM2 as a novel A-type-lamin-associated INM protein involved in nuclear structure organization...
Differential selection of Golgi proteins by COPII Sec24 isoforms in procyclic Trypanosoma bruceiLars Demmel
Max F Perutz Laboratories, University of Vienna, Medical University of Vienna, Dr Bohrgasse 9, A 1030 Vienna, Austria
Traffic 12:1575-91. 2011..Together, these data suggest that TbSec24 paralogs can differentiate among proteins destined for the Golgi...
