Research Topics
Genomes and GenesSpecies | Sabine IvancsitsSummaryAffiliation: University of Vienna Country: Austria Publications
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Publications
Intermittent extremely low frequency electromagnetic fields cause DNA damage in a dose-dependent waySabine Ivancsits
Division of Occupational Medicine, University Hospital AKH, Waehringer Guertel 18 20, 1090 Vienna, Austria
Int Arch Occup Environ Health 76:431-6. 2003..The validity of such findings can be corroborated only by demonstration of dose-dependent DNA-damaging effects of ELF-EMFs in cells of human origin in vitro...
Induction of 8-hydroxy-2'-deoxyguanosine by cobalt(II) and hydrogen peroxide in vitroSabine Ivancsits
Department of Occupational Medicine, University of Vienna, Austria
J Toxicol Environ Health A 65:665-76. 2002..026 +/- 0.695 vs. 1.395 +/- 0.433 8-OHdG/10(5) dG) at all concentrations. Our data indicate that in the presence of H2O2, Co(II) stimulates the in vitro formation of 8-OHdG...
Induction of DNA strand breaks by intermittent exposure to extremely-low-frequency electromagnetic fields in human diploid fibroblastsSabine Ivancsits
Division of Occupational Medicine, University Hospital AKH, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Mutat Res 519:1-13. 2002..Our data strongly indicate a genotoxic potential of intermittent EMF. This points to the need of further studies in vivo and consideration about environmental threshold values for ELF exposure...
Vanadate induces DNA strand breaks in cultured human fibroblasts at doses relevant to occupational exposureSabine Ivancsits
Division of Occupational Medicine, University Hospital AKH, University of Vienna, Waehringer Guertel 18 20, Austria
Mutat Res 519:25-35. 2002..We conclude that exposure of human fibroblasts to vanadate effectively causes DNA strand breaks, and co-exposure of cells to other genotoxic agents may result in persistent DNA damage...
Orthostatic intolerance is not necessarily related to a specific mutation (Ala457Pro) in the human norepinephrine transporter geneSabine Ivancsits
Division of Occupational Medicine, University of Vienna, Austria
Am J Med Sci 325:63-5. 2003....
Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fieldsSabine Ivancsits
Division of Occupational Medicine, University of Vienna, University Hospital AKH, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Mech Ageing Dev 124:847-50. 2003..This response was clearly more pronounced in cells from older donors, which could point to an age-related decrease of DNA repair efficiency of ELF-EMF induced DNA strand breaks...
Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fieldsSabine Ivancsits
Division of Occupational Medicine, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria
Mutat Res 583:184-8. 2005....
No effects of intermittent 50 Hz EMF on cytoplasmic free calcium and on the mitochondrial membrane potential in human diploid fibroblastsAlexander Pilger
Division of Occupational Medicine, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
Radiat Environ Biophys 43:203-7. 2004..Therefore, it is suggested that ELF-EMF-induced DNA strand breaks are unlikely to be caused by intracellular changes that affect [Ca2+]i and/or DeltaPsi(m)...
Basal levels of DNA strand breaks in human leukocytes determined by comet assayElisabeth Diem
Department of Occupational Medicine, University of Vienna, Austria
J Toxicol Environ Health A 65:641-8. 2002..Our data encourage the application of the used classification model for a sensitive and fast quantification of DNA damage. Results in this study are in agreement with most of the earlier investigations...
Chromosomal damage in human diploid fibroblasts by intermittent exposure to extremely low-frequency electromagnetic fieldsRobert Winker
Division of Occupational Medicine, Medical University of Vienna, Wahringer Gurtel 18 20, Vienna A 1090, Austria
Mutat Res 585:43-9. 2005..Our data strongly indicate a clastogenic potential of intermittent low-frequency electromagnetic fields, which may lead to considerable chromosomal damage in dividing cells...
