Research Topics
| Wolfgang M SchmidtSummaryAffiliation: Medical University of Vienna Country: Austria Publications
| Collaborators
|
Detail Information
Publications
In-vivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation modelWolfgang M Schmidt
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
Pharmacogenet Genomics 18:109-20. 2008..To gain insight into molecular mechanisms of anti-inflammatory effects of statins, we have studied global gene expression in circulating leucocytes in an in-vivo model of acute inflammation following statin administration...
In vivo profile of the human leukocyte microRNA response to endotoxemiaWolfgang M Schmidt
Department of Clinical Pharmacology, Division of Pharmacogenetics and Imaging, Medical University of Vienna, A 1090 Vienna, Austria
Biochem Biophys Res Commun 380:437-41. 2009..The miRNAs and their potential target genes identified herein contribute to the understanding of the complex transcriptional program of innate immunity initiated by pathogens...
Ramipril modulates circadian gene expression in skeletal muscleRobert Sauermann
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
Pharmacogenet Genomics 21:751-9. 2011..To identify these mechanisms, we studied the effect of ACE-inhibition on gene expression in skeletal muscle, a primary target tissue for insulin in glucose homeostasis...
Forearm vasodilator reactivity in homozygous carriers of the 9p21.3 rs1333049 G>C polymorphismStefan Aschauer
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
Eur J Clin Invest 40:700-5. 2010..The aim of the present case-control study was to test whether this chromosome 9p21.3 locus, represented by the rs1333049 variant, is associated with altered vasodilator resistance vessel function in healthy young volunteers...
Dissecting progressive stages of 5-fluorouracil resistance in vitro using RNA expression profilingWolfgang M Schmidt
VBC-GENOMICS Bioscience Research Inc, Vienna, Austria
Int J Cancer 112:200-12. 2004..This study emphasizes the understanding of resistance as a time-depending process: the cell is particularly challenged at the beginning of this process, while acquisition of the high-resistance phenotype seems to be less demanding...
Suppression of human melanoma tumor growth in SCID mice by a human high molecular weight-melanoma associated antigen (HMW-MAA) specific monoclonal antibodyChristine Hafner
Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, Austria
Int J Cancer 114:426-32. 2005..28S. Our results suggest that anti-HMW-MAA mAbs may represent useful reagents to apply passive immunotherapy to patients with malignant melanoma...
Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cellsGerwin Heller
Division of Oncology, Department of Medicine I, Medical University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
Cancer Res 68:44-54. 2008....
