Research Topics
| Markus H HoffmannSummaryAffiliation: Medical University of Vienna Country: Austria Publications
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Detail Information
Publications
Gait changes precede overt arthritis and strongly correlate with symptoms and histopathological events in pristane-induced arthritisMarkus H Hoffmann
Division of Rheumatology, Internal Medicine III, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Arthritis Res Ther 12:R41. 2010..To investigate this issue a detailed analysis of the pathologic changes occurring during the prodromal and early stages of PIA was performed...
Nucleic acid-stimulated antigen-presenting cells trigger T cells to induce disease in a rat transfer model of inflammatory arthritisMarkus H Hoffmann
Division of Rheumatology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
J Autoimmun 36:288-300. 2011..Our data explain the specific selection of hnRNP-A2/B1 as autoantigen in RA and reveal the requirement of interaction between innate and adaptive immunity to initiate and drive inflammation in autoimmune arthritis...
The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritisMarkus H Hoffmann
Department of Rheumatology, Medical University of Vienna, Vienna, Austria
J Immunol 179:7568-76. 2007..Taken together, these data suggest hnRNP-A2 to be among the primary inducers of autoimmunity in PIA. Therefore, this Ag might play a pivotal role in the pathogenesis of PIA and possibly also human RA...
Nucleic acid-associated autoantigens: pathogenic involvement and therapeutic potentialMarkus H Hoffmann
Division of Rheumatology, Internal Medicine III, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
J Autoimmun 34:J178-206. 2010..Furthermore, recent advances in immunotherapy such as antigen-specific approaches targeted at nucleic acid-binding antigens are discussed...
