Research Topics
| Julian N TrollorSummaryAffiliation: University of New South Wales Country: Australia Publications
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Detail Information
Publications
Age shall not weary them: mental health in the middle-aged and the elderlyJulian N Trollor
School of Psychiatry, University of New South Wales and Neuropsychiatric Institute, Euroa Centre, Prince of Wales Hospital, Randwick, NSW, Australia
Aust N Z J Psychiatry 41:581-9. 2007..The aim of the present paper was to provide the first direct comparison of the prevalence and demographic correlates of ICD-10 anxiety and affective disorders in the middle-aged and the elderly...- Combined cerebral blood flow effects of a cholinergic agonist (milameline) and a verbal recognition task in early Alzheimer's diseaseJulian N Trollor
School of Psychiatry, University of New South Wales, Sydney, Australia
Psychiatry Clin Neurosci 60:616-25. 2006.... - Attention deficit hyperactivity disorder in adults: conceptual and clinical issuesJ N Trollor
Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW
Med J Aust 171:421-5. 1999..Clinicians should be aware of this potentially treatable disorder in young adults presenting with psychological difficulties and a history of childhood ADHD symptoms... - Systemic inflammation is associated with MCI and its subtypes: the Sydney Memory and Aging StudyJulian N Trollor
Department of Developmental Disability Neuropsychiatry, University of New South Wales, 34 Botany Road, Sydney, NSW 2052, Australia
Dement Geriatr Cogn Disord 30:569-78. 2010..This study examines the relationship between systemic inflammation and MCI subtypes... - Neuroleptic malignant syndrome associated with atypical antipsychotic drugsJulian N Trollor
School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia
CNS Drugs 23:477-92. 2009..Both these issues have relevance for the identification of atypical or milder forms of NMS, which are sometimes seen with atypical antipsychotic drugs... - Regional cerebral blood flow deficits in mild Alzheimer's disease using high resolution single photon emission computerized tomographyJulian N Trollor
School of Psychiatry, University of New South Wales, Sydney, Australia
Psychiatry Clin Neurosci 59:280-90. 2005..Discriminant function analysis indicated that rCBF in the prefrontal polar regions achieved the best classification of cases. SPECT has utility in the diagnostic assessment of AD if standardized and semiquantitative techniques are used... - A high-resolution single photon emission computed tomography study of verbal recognition memory in Alzheimer's diseaseJulian N Trollor
School of Psychiatry, University of New South Wales, Randwick, Australia
Dement Geriatr Cogn Disord 21:267-74. 2006..In view of the recent technological advances and its ease of availability, we used single photon emission computed tomography (SPECT) to examine the performance of early Alzheimer's disease (AD) subjects on a verbal recognition memory task... - Prevalence of mental disorders in the elderly: the Australian National Mental Health and Well-Being SurveyJulian N Trollor
Neuropsychiatric Institute, Prince of Wales Hospital, Randwick, NSW, Australia
Am J Geriatr Psychiatry 15:455-66. 2007.... - Neuroanatomical correlates of cognitive performance in late lifeHaobo Zhang
Brain and Ageing Research Program, School of Psychiatry, University of New South Wales, Sydney, N S W, Australia
Dement Geriatr Cogn Disord 32:216-26. 2011..Examination of a large epidemiologically acquired sample with high-resolution magnetic resonance imaging has the potential to enhance the evidence in this field... - Risk profiles of subtypes of mild cognitive impairment: the sydney memory and ageing studyPerminder S Sachdev
Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, Australia
J Am Geriatr Soc 60:24-33. 2012..To compare the risk profiles of mild cognitive impairment (MCI) subtypes in a population-based elderly sample... - The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 yearsPerminder S Sachdev
Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, Australia
Int Psychogeriatr 22:1248-64. 2010.... - The relationship between cortical sulcal variability and cognitive performance in the elderlyTao Liu
School of Design, Communication and IT, The University of Newcastle, Callaghan, NSW, Australia
Neuroimage 56:865-73. 2011..The results suggest that regionally specific sulcal morphology is associated with cognitive function in elderly individuals... - The relationship of neuropsychological function to instrumental activities of daily living in mild cognitive impairmentSimone Reppermund
Brain and Ageing Research Program, Faculty of Medicine, School of Psychiatry, University of New South Wales, NSW, Australia
Int J Geriatr Psychiatry 26:843-52. 2011..The aims of the present study were to examine differences in IADL between individuals with MCI and cognitively normal elderly, and to examine the relationships of IADL with cognitive functions... - Effect of different impairment criteria on prevalence of “objective” mild cognitive impairment in a community sampleNicole A Kochan
Brain and Ageing Research Program, School of Psychiatry, The University of New South Wales, Sydney, Australia
Am J Geriatr Psychiatry 18:711-22. 2010..The aims of this study were to investigate the effect of varying the criteria used to determine cognitive impairment (CI) on prevalence and case definition and to examine comparability of different criteria... - Cortical responses to a graded working memory challenge predict functional decline in mild cognitive impairmentNicole A Kochan
Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
Biol Psychiatry 70:123-30. 2011..We observed greater deactivation of posteromedial cortex (PMC) under conditions of increased WM load in MCI compared with control subjects. Our objective here is to test whether this paradigm can predict ensuing functional decline... - Diffusion tensor imaging of the posterior cingulate is a useful biomarker of mild cognitive impairmentTerence C Chua
School of Psychiatry, University of New South Wales, NSW, Australia
Am J Geriatr Psychiatry 17:602-13. 2009..Biomarkers may help identify individuals at greatest risk of progressive decline. The authors examine a novel neuroimaging technique, diffusion tensor imaging (DTI) as a potential biomarker of MCI... - Grey matter atrophy of basal forebrain and hippocampus in mild cognitive impairmentHaobo Zhang
Brain and Ageing Research Program, School of Psychiatry, University of New South Wales, Sydney, Australia
J Neurol Neurosurg Psychiatry 82:487-93. 2011..In addition, a slight but statistically significant difference was found in the left hippocampal volume between APOE ?4 allele carriers and non-carriers, consistent with prior studies... - Prevalence and predictors of “subjective cognitive complaints” in the Sydney Memory and Ageing StudyMelissa J Slavin
Brain and Ageing Research Program, School of Psychiatry, The University of New South Wales, Sydney, Australia
Am J Geriatr Psychiatry 18:701-10. 2010.... - Automated detection of amnestic mild cognitive impairment in community-dwelling elderly adults: a combined spatial atrophy and white matter alteration approachYue Cui
School of Design, Communication and Information Technology, University of Newcastle, Callaghan, NSW, Australia
Neuroimage 59:1209-17. 2012..Given its high level of performance, our classification schema could facilitate the early detection of aMCI in community-dwelling elderly adults... - Predicting the development of mild cognitive impairment: a new use of pattern recognitionYue Cui
School of Design, Communication and Information Technology, University of Newcastle, Callaghan, NSW, Australia
Neuroimage 60:894-901. 2012..Identification at this stage will facilitate the early start of interventions designed to prevent or slow the development of Alzheimer's disease and other dementias... - Gray matter atrophy patterns of mild cognitive impairment subtypesHaobo Zhang
Brain and Ageing Research Program, School of Psychiatry, University of New South Wales, Sydney, Australia
J Neurol Sci 315:26-32. 2012..MCI subtypes displayed specific patterns of GM atrophy that appear to be related to their various clinical presentations, which implies that underlying mechanisms of MCI subtypes are different... - Cognitive functioning in older twins: the Older Australian Twins StudyPerminder S Sachdev
Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, and Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, New South Wales, Australia
Australas J Ageing 30:17-23. 2011..To examine the concordance rates of common medical conditions and neurocognitive performance in monozygotic (MZ) and dizygotic (DZ) older twins... - Effects of sociodemographic and health variables on Mini-Mental State Exam scores in older AustraliansTracy M Anderson
School of Psychiatry, University of New South Wales, the Clinical Research Unit for Anxiety and Depression, Darlinghurst, New South Wales, Australia
Am J Geriatr Psychiatry 15:467-76. 2007.... - A comprehensive neuropsychiatric study of elderly twins: the Older Australian Twins StudyPerminder S Sachdev
Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Australia
Twin Res Hum Genet 12:573-82. 2009..The cohort will be assessed every two years, with in-depth assessments being repeated. OATS offers an excellent opportunity for collaboration with other similar studies as well as researchers who share the same interests... - Genetic influences on five measures of processing speed and their covariation with general cognitive ability in the elderly: the older Australian twins studyTeresa Lee
Brain and Aging Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia
Behav Genet 42:96-106. 2012..These findings suggest that the different PS measures, as well as GCA were to a large extent influenced by the same set of genes and that the relationship between PS and GCA is entirely due to shared-genetic influences... - Abnormalities of the Fornix in Mild Cognitive Impairment are Related to Episodic Memory LossLin Zhuang
Brain and Ageing Research Program, School of Psychiatry, University of New South Wales, Randwick, NSW, Australia
J Alzheimers Dis 29:629-39. 2012..This study suggests that microstructural alteration of the fornix is a contributor to early episodic memory dysfunction in non-demented individuals... - Genetic influences on cognitive functions in the elderly: a selective review of twin studiesTeresa Lee
Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, NSW, Australia
Brain Res Rev 64:1-13. 2010..It highlights the need for more research, with consistent and appropriate cognitive measures, with data obtained from larger and more geographically and culturally diverse twin samples... - Brain ageing in the new millenniumJ N Trollor
School of Psychiatry, University of New South Wales and Neuropsychiatric Institute, The Prince of Wales Hospital, Sydney, Australia
Aust N Z J Psychiatry 35:788-805. 2001..This paper examines the current literature pertaining to brain ageing. The objective of this review is to provide an overview of the effects of ageing on brain structure and function and to examine possible mediators of these changes... - How high a dose of stimulant medication in adult attention deficit hyperactivity disorder?P S Sachdev
School of Psychiatry, University of New South Wales and Neuropsychiatric Institute, Prince of Wales Hospital, Randwick, Australia
Aust N Z J Psychiatry 34:645-50. 2000..It attempts to arrive at a reasonable upper limit of dosage for clinical purposes... - Neuropsychological functioning of adults with attention deficit hyperactivity disorderA J Walker
Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia
J Clin Exp Neuropsychol 22:115-24. 2000..The predictive power of the tests was poor in discriminating ADHD from psychiatric disorder. Implications for the clinical diagnosis of ADHD are discussed... - Electroconvulsive treatment of neuroleptic malignant syndrome: a review and report of casesJ N Trollor
Neuropsychiatric Institute, The Prince of Wales Hospital, Randwick, New South Wales, Australia
Aust N Z J Psychiatry 33:650-9. 1999..We review 45 published case reports of ECT for NMS and describe nine new cases, to examine its effectiveness, the likelihood of adverse reactions, and the theoretical implications of such treatment... - The case of a 48 year-old woman with bizarre and complex delusionsClement T Loy
Prince of Wales Medical Research Institute, Barker Street, Randwick, Sydney, NSW 2031, Australia
Nat Rev Neurol 6:175-9. 2010..Her psychosis progressed despite receiving high doses of antipsychotics. The patient's father also had a psychotic episode in his 40s. He subsequently developed motor neuron disease, which caused his death at 68 years of age...