Research Topics
Genomes and GenesSpecies | D J TorpySummaryAffiliation: University of Queensland Country: Australia Publications
| Collaborators
|
Detail Information
Publications
Association of hypertension and hypokalemia with Cushing's syndrome caused by ectopic ACTH secretion: a series of 58 casesDavid J Torpy
University of Queensland, Department of Medicine, Greenslopes Hospital, Newdegate Street, Brisbane, Queensland 4120, Australia
Ann N Y Acad Sci 970:134-44. 2002....- Leptin levels are suppressed in primary aldosteronismD J Torpy
Developmental Endocrinology Branch, National Institutes of Health, Bethesda, MD, USA
Horm Metab Res 31:533-6. 1999..Further studies are indicated to identify the mechanism of plasma leptin suppression in primary aldosteronism... - The insulin hypoglycemia test: hypoglycemic criteria and reproducibilityE J Nye
Neuroendocrine Research Unit, Department of Medicine, Brisbane, The University of Queensland, Queensland, Australia
J Neuroendocrinol 13:524-30. 2001..Overall, the cortisol response to hypoglycemia is more reproducible than the ACTH response but, in an individual subject, the difference in peak cortisol between two IHTs may exceed 100 nmol/l... - Early rise in blood pressure following administration of adrenocorticotropic hormone-[1-24] in humansR V Jackson
Neuroendocrine Research Unit, Department of Medicine, University of Queensland, Greenslopes Private Hospital, Brisbane, Queensland 4120, Australia
Clin Exp Pharmacol Physiol 28:773-5. 2001..5. The cardiovascular consequences of therapeutic use of ACTH are well recognized. This results of the present study suggest that even diagnostic administration of ACTH, delivered over a few hours, may raise blood pressure... - Corticotropin-releasing hormone and inflammationE L Webster
Pediatric Endocrinology Section, National Institute of Child Health and Development, National Institutes of Health, Bethesda, Maryland 20892, USA
Ann N Y Acad Sci 840:21-32. 1998.... - Leptin and interleukin-6 in sepsisD J Torpy
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892-1862, USA
Horm Metab Res 30:726-9. 1998.... - Hyper- and hypoaldosteronismD J Torpy
National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
Vitam Horm 57:177-216. 1999..This review aims to provide a survey of the clinical disorders of aldosterone excess and deficiency and their clinical management, with a focus on primary aldosteronism and isolated aldosterone deficiency... - A novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22)A R Lafferty
Unit on Genetics and Endocrinology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Building 10, Room 10N262, 10 Center Drive, MSC1862, Bethesda, Maryland 20892 1862, USA
J Med Genet 37:831-5. 2000..This is the first identified locus for FH-II; its molecular elucidation may provide further insight into the aetiology of primary aldosteronism... - Adrenocorticotropin stimulation tests in patients with hypothalamic-pituitary disease: low dose, standard high dose and 8-h infusion testsE J Nye
Department of Medicine, The University of Queensland, Brisbane, Australia
Clin Endocrinol (Oxf) 55:625-33. 2001..1 microg) or a high dose prolonged infusion does not greatly improve the sensitivity of ACTH [1-24] testing. Dynamic tests that provide a central stimulus remain preferable in the assessment of patients with suspected ACTH deficiency... - Urocortin and inflammation: confounding effects of hypotension on measures of inflammationD J Torpy
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892 1862, USA
Neuroimmunomodulation 6:182-6. 1999..The use of inflammatory models which rely on extravasation may be inappropriate for the study of substances that produce hypotension... - Greater replication and differentiation of preadipocytes in inherited corticosteroid-binding globulin deficiencyJ M Joyner
Department of Medicine, Redland Hospital, Cleveland, Queensland 4163, Australia
Am J Physiol Endocrinol Metab 284:E1049-54. 2003..Furthermore, these observations may be relevant to obesity occurring with suppressed CBG concentrations associated with hyperinsulinemia... - Familial corticosteroid-binding globulin deficiency due to a novel null mutation: association with fatigue and relative hypotensionD J Torpy
Department of Medicine, University of Queensland, Greenslopes Private Hospital, Brisbane, Queensland 4120, Australia
J Clin Endocrinol Metab 86:3692-700. 2001..As idiopathic fatigue disorders are associated with relatively low plasma cortisol, abnormalities of corticosteroid-binding globulin may be pathogenic... - New genetic insights in familial hyperaldosteronismRichard V Jackson
Department of Medicine, University of Queensland, Greenslopes Private Hospital, Newdegate Street, Brisbane, Queensland 4120, Australia
Ann N Y Acad Sci 970:77-88. 2002..This is the first identified locus for FH-II. Several possible candidate genes have been localized to the 7p22 region. The precise genetic cause of FH-II remains to be elucidated... - Glucocorticoid receptor polymorphisms and post-traumatic stress disorderAnthony W Bachmann
Department of Medicine, University of Queensland, Greenslopes Private Hospital, Brisbane, QLD 4120, Australia
Psychoneuroendocrinology 30:297-306. 2005..Our PTSD group did not display GC hypersensitivity, as measured by the LD-DST and DVVA. In a subset of PTSD patients with the BclI GG genotype, CAPS scores and basal cortisol levels were negatively correlated... - Association between chronic fatigue syndrome and the corticosteroid-binding globulin gene ALA SER224 polymorphismDavid J Torpy
University of Queensland Department of Medicine, Greenslopes Hospital, Brisbane, Queensland, Australia
Endocr Res 30:417-29. 2004..Homozygosity for the serine allele of the CBG gene may predispose to CFS, perhaps due to an effect on hypothalamic-pituitary-adrenal axis function related to altered CBG-cortisol transport function or immune-cortisol interactions... - Plasma free cortisol fraction reflects levels of functioning corticosteroid-binding globulinJohn G Lewis
Steroid and Immunobiochemistry Laboratory, Canterbury Health Laboratories, PO Box 151 Christchurch, New Zealand
Clin Chim Acta 359:189-94. 2005..However little is known about the distribution of free cortisol in plasma where CBG is inactivated or in congenital CBG deficiency... - Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of HealthIoannis Ilias
Pediatric and Reproductive Endocrinology Branch, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1109, USA
J Clin Endocrinol Metab 90:4955-62. 2005..Initial failed localization is common and suggests pulmonary carcinoid. Although only 47% achieved cure, survival is good except in patients with small-cell lung cancer, medullary thyroid cancer, and gastrinoma... - Reduced maternal corticosteroid-binding globulin and cortisol levels in pre-eclampsia and gamete recipient pregnanciesJui T Ho
Hanson Institute, University of Adelaide, and Endocrine and Metabolic Unit of the Royal Adelaide Hospital, Adelaide, South Australia, Australia
Clin Endocrinol (Oxf) 66:869-77. 2007..To measure and contrast maternal cortisol and corticosteroid-binding globulin (CBG) levels in pregnancies with normal outcomes, pre-eclampsia, intrauterine growth restriction (IUGR) and in gamete recipients...