Research Topics
Species | David W ReidSummaryAffiliation: University of Tasmania Country: Australia Publications
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Detail Information
Publications
Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary diseaseSukhwinder S Sohal
NHMRC National Centre for Research Excellence in Chronic Respiratory Disease, Menzies Research Institute, 17 Liverpool Street, Hobart, 7000, Australia
Respir Res 12:130. 2011..Such changes are likely hallmarks of epithelial mesenchymal transition (EMT). We aimed to confirm the epithelial origin of these Rbm cells, and to exclude potential confounding by infiltrating inflammatory cells...- Tolerance and rebound with zafirlukast in patients with persistent asthmaDavid W Reid
Respiratory Research Group, Menzies Research Institute, University of Tasmania Hobart, Tasmania, Australia
J Negat Results Biomed 7:3. 2008..The potential for tolerance to develop to zafirlukast, a cysteinyl leukotriene (CysLT) receptor antagonist (LRA) in persistent asthma, has not been specifically examined... - "Bong lung" in cystic fibrosis: a case reportZoe Gao
Departments of Respiratory Medicine, Royal Hobart Hospital, Liverpool Street, Hobart, Tasmania, 7000, Australia
J Med Case Reports 4:371. 2010..The underlying mechanism for bullae formation is uncertain, but probably relates to direct lung toxicity and repeated barotrauma as the smoker performs frequent valsalva manoeuvres in an attempt to derive a greater drug effect... - Iron, Pseudomonas aeruginosa and cystic fibrosisD W Reid
Discipline of Medicine, University of Tasmania Clinical School, 43 Collins Street, Hobart, Tasmania, 7000, Australia
Microbiology 150:516; discussion 516-8. 2004 - Increased airway iron as a potential factor in the persistence of Pseudomonas aeruginosa infection in cystic fibrosisD W Reid
Cardiorespiratory Research Group, School of Medicine, University of Tasmania, Hobart, Australia
Eur Respir J 30:286-92. 2007..aeruginosa during an exacerbation. In conclusion, the present study suggests that increased airway iron may be important to Pseudomonas aeruginosa persistence in cystic fibrosis... - Atypical presentation of acute pancreatitis in a man with pancreatic insufficiency and cystic fibrosis: a case reportMalcolm Turner
Department of Respiratory Medicine, Royal Hobart Hospital, Tasmania, Australia
J Med Case Reports 4:275. 2010..Whether acute pancreatitis can occur in pancreatically insufficient individuals with cystic fibrosis remains a matter of debate... - Oxidative stress and lipid-derived inflammatory mediators during acute exacerbations of cystic fibrosisDavid W Reid
Cardio Respiratory Research Group, University of Tasmania Medical School, Hobart, Tasmania, Australia
Respirology 12:63-9. 2007.... - Role of lung iron in determining the bacterial and host struggle in cystic fibrosisD W Reid
Menzies Research Institute, Hobart, Tasmania
Am J Physiol Lung Cell Mol Physiol 297:L795-802. 2009.... - Bronchodilator reversibility, airway eosinophilia and anti-inflammatory effects of inhaled fluticasone in COPD are not relatedDavid W Reid
Respiratory Research Group, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
Respirology 13:799-809. 2008..In particular, it is not known whether BDR is associated with underlying airway eosinophilia and whether BDR is predictive of a better response to inhaled corticosteroid (ICS) treatment... - Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPDYudong Wen
Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
Int J Chron Obstruct Pulmon Dis 5:327-34. 2010.... - Iron-binding compounds impair Pseudomonas aeruginosa biofilm formation, especially under anaerobic conditionsChe Y O'May
Menzies Research Institute, University of Tasmania Clinical School, Hobart, Tasmania 7001, Australia
J Med Microbiol 58:765-73. 2009.... - Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional studyAmir Soltani
Respiratory Research Group, Menzies Research Institute, University of Tasmania, 17 Liverpool St, Hobart, 7000, Australia
Respir Res 11:105. 2010..We conducted an initial pilot study comparing BB from COPD patients with nonsmoking controls. This pilot study suggested the presence of reticular basement membrane (Rbm) fragmentation and altered vessel distribution in COPD... - Bronchial hyperresponsiveness and the bronchiolitis obliterans syndrome after lung transplantationDavid W Reid
Lung Transplant Service, Department of Respiratory Medicine, The Alfred Hospital and Monash University, Melbourne, Australia
J Heart Lung Transplant 24:489-92. 2005.... - Bacterial cyanogenesis occurs in the cystic fibrosis lungK Sanderson
Respiratory Research Group, Menzies Research Institute, University of Tasmania, Hobart, Australia
Eur Respir J 32:329-33. 2008..Cyanide is likely to be a potentially important virulence factor in Pseudomonas aeruginosa-infected cystic fibrosis patients... - Population-based study of cystic fibrosis disease severity and haemochromatosis gene mutationsUpasna Pratap
Respiratory Research Group, Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7001, Australia
Respirology 15:141-9. 2010..Haemochromatosis (HFE) mutations increase the risk of bowel obstruction in cystic fibrosis (CF), but the impact on other disease manifestations is unknown... - Poor clinical outcomes associated with a multi-drug resistant clonal strain of Pseudomonas aeruginosa in the Tasmanian cystic fibrosis populationRICHARD BRADBURY
Respiratory Research Group, Menzies Research Institute, University of Tasmania, Collins Street, Hobart, Tasmania, Australia
Respirology 13:886-92. 2008..Patients in Tasmania are geographically dispersed and when this study was conducted (2003) there was no central CF clinic, with patients receiving treatment in regional hospitals... - Biofilm differentiation and dispersal in mucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosisSylvia M Kirov
School of Medicine, University of Tasmania Clinical School, 43 Collins St, Hobart, Tasmania 7001, Australia
Microbiology 153:3264-74. 2007..aeruginosa in the CF airway... - Anaerobic culture conditions favor biofilm-like phenotypes in Pseudomonas aeruginosa isolates from patients with cystic fibrosisDavid W Reid
School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
FEMS Immunol Med Microbiol 48:373-80. 2006..aeruginosa isolates tested. In vitro models used to research CF isolate biofilm growth need to take the above properties of these strains into account... - Distinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same diseaseAmir Soltani
Respiratory Research Group Descipline of Pathology, Menzies Research Institute, University of Tasmania, Hobart Queensland Institute of Medical Research, Brisbane Mercy Healthcare Victoria, Victoria, Australia
Histopathology 60:964-70. 2012..05] was also increased in COPD compared to normal subjects and asthmatics. Conclusions:? The characteristics of Rbm remodelling are quite different in asthma and COPD... - Iron deficiency in cystic fibrosis: relationship to lung disease severity and chronic Pseudomonas aeruginosa infectionDavid W Reid
Cystic Fibrosis Service, Department of Respiratory Medicine, Monash University Medical School, Alfred Hospital, Prahran, Melbourne, Vic, Australia
Chest 121:48-54. 2002.... - Airway inflammation and anti-protease defences rapidly improve during treatment of an acute exacerbation of COPDSushil Pant
Cardio Respiratory Research Group, Menzies Research Institute, University of Tasmania, Australia
Respirology 14:495-503. 2009..An observational study was performed to determine how rapidly conventional treatment improves airway inflammation in patients admitted to hospital with AECOPD... - Virulence gene distribution in clinical, nosocomial and environmental isolates of Pseudomonas aeruginosaR S Bradbury
Microbiology Department, Royal Hobart Hospital, Liverpool Street, Hobart, TAS, Australia
J Med Microbiol 59:881-90. 2010..01) when compared to other clinical isolates (P<0.01), which may indicate decreased virulence. No specific virulence factor genotype was associated with the cystic fibrosis epidemic strains tested... - Airway cell and cytokine changes in early asthma deterioration after inhaled corticosteroid reductionY H Khor
Respiratory Research Group, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
Clin Exp Allergy 37:1189-98. 2007..We aimed at assessing the underlying pathological changes in relation to clinical deterioration... - Epidemiology of Pseudomonas aeruginosa in a tertiary referral teaching hospitalR S Bradbury
Microbiology Department, Royal Hobart Hospital, Cardio Respiratory Research Group, Menzies Research Institute, School of Medicine, University of Tasmania, Hobart, Tasmania
J Hosp Infect 73:151-6. 2009..P. aeruginosa in the non-CF settings was found to be panmictic, and no cross-infection or acquisition of hospital environment strains by patients was observed... - Antimicrobial susceptibility testing of cystic fibrosis and non-cystic fibrosis clinical isolates of Pseudomonas aeruginosa: a comparison of three methodsR S Bradbury
CF Research Group, Menzies Research Institute, School of Medicine, University of Tasmania, Hobart, Australia
Br J Biomed Sci 68:1-4. 2011..aeruginosa infection... - Airway distensibility in normal and asthmatic subjects and partitioning of the Fowler dead spaceDavid P Johns
Cardio Respiratory Research Group, School of Medicine, University of Tasmania, Hobart, Tasmania 7000, Australia
Appl Physiol Nutr Metab 31:460-6. 2006..005). We conclude that in both asthmatic and healthy subjects, the major component of DeltaVDF was DeltaVDp1 and not DeltaVDp2, as originally hypothesized. We believe our results are reflecting the degree of asynchronous airway emptying... - BAL eotaxin and IL-5 in asthma, and the effects of inhaled corticosteroid and beta2 agonistBryce N Feltis
Respiratory Research Group, Tasmanian School of Medicine, University of Tasmania, Hobart, Tasmania, Australia
Respirology 9:507-13. 2004..It is hypothesised that changes in airway eosinophils would be related to eosinophil cytokines... - Increased vascular permeability precedes cellular inflammation as asthma control deterioratesY H Khor
Respiratory Research Group, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
Clin Exp Allergy 39:1659-67. 2009..We prospectively assessed the vascular changes accompanying worsening of asthma control by using an inhaled corticosteroid (ICS) dose-reduction model... - Biosignificance of bacterial cyanogenesis in the CF lungR D Anderson
School of Medicine, University of Tasmania, Hobart, Tasmania, 7001, Australia
J Cyst Fibros 9:158-64. 2010..This review discusses the implications of cyanogenesis in the CF airway in terms of bacterial ecology, host immune response, progression of lung disease and potential treatment options... - Nonpharmacological and pharmacological interventions to prevent or reduce airway remodellingE H Walters
Cardio Respiratory Research Group, Menzies Research Institute, University of Tasmania, 43 Collins Street, Hobart 7001, Australia
Eur Respir J 30:574-88. 2007..The areas where it is believed urgent research needs to be focused have also been highlighted... - Decreased lung capillary blood volume post-exercise is compensated by increased membrane diffusing capacityD P Johns
Discipline of Medicine, School of Medicine, University of Tasmania, 7001 Hobart, Tasmania, Australia
Eur J Appl Physiol 93:96-101. 2004..It is suggested that this effect is brought about by the reorientation of red blood cells within the pulmonary capillaries following exercise... - Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthmaC Ward
Department of Respiratory Medicine, Alfred Hospital and Monash University Medical School, Melbourne, Australia
Am J Respir Crit Care Med 164:1718-21. 2001..Our findings support the hypothesis that DeltaVD is a physiologic test that is reflective of airway remodeling... - Effects of inhaled fluticasone on angiogenesis and vascular endothelial growth factor in asthmaB N Feltis
Tasmanian School of Medicine, 43 Collins St, Hobart, Tasmania, Australia 7001
Thorax 62:314-9. 2007..A study was undertaken to explore angiogenic modulation by ICS and its likely regulation via vascular endothelial growth factor (VEGF), its receptors and the angiopoietins... - Exhaled nitric oxide continues to reflect airway hyperresponsiveness and disease activity in inhaled corticosteroid-treated adult asthmatic patientsDavid W Reid
Department of Respiratory Medicine and Monash University Medical School, Alfred Hospital, Melbourne, Victoria, Australia
Respirology 8:479-86. 2003..However, whether eNO levels reflect disease activity in symptomatic asthmatics receiving moderate doses of inhaled corticosteroid (ICS) is more uncertain... - Cystic fibrosis: ironing out the problem of infection?David W Reid
Am J Physiol Lung Cell Mol Physiol 295:L23-4. 2008 - Bronchodilator reversibility testing: laboratory practices in Australia and New ZealandBrigitte M Borg
Department of Allergy, Immunology and Respiratory Medicine, The Alfred Hospital and Monash University Medical School, Melbourne, Vic
Med J Aust 180:610-3. 2004..This may have a significant effect on the diagnosis and management of patients. Laboratories should report the method used to assess bronchodilator response...