Research Topics
| David V PowSummaryAffiliation: University of Queensland Country: Australia Publications
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Detail Information
Publications
Neuronal expression of splice variants of "glial" glutamate transporters in brains afflicted by Alzheimer's disease: unmasking an intrinsic neuronal propertyDavid V Pow
UQ Centre for Clinical Research and Perinatal Research Centre, Royal Brisbane and Womens Hospital, The University of Queensland, Building 71 918 Herston, Brisbane, QLD 4029, Australia
Neurochem Res 34:1748-57. 2009....- Glial glutamate transporter expression patterns in brains from multiple mammalian speciesSusan M Williams
Department of Physiology and Pharmacology, School of Biomedical Sciences, University of Queensland, Brisbane, Australia
Glia 49:520-41. 2005..Collectively our data suggest that assumptions as to the roles of glutamate transporters in any species may need to be tested empirically... - Differential expression of the GABA transporters GAT-1 and GAT-3 in brains of rats, cats, monkeys and humansDavid V Pow
Department of Physiology and Pharmacology, School of Biomedical Sciences, University of Queensland, Brisbane, 4072, Australia
Cell Tissue Res 320:379-92. 2005..We suggest that differences in GAT distribution, especially the expression of GAT-3 by oligodendrocytes in humans, must be accommodated in extrapolating rodent models of GABA homeostasis to humans... - Structural remodeling of gray matter astrocytes in the neonatal pig brain after hypoxia/ischemiaSusan M Sullivan
UQ Centre for Clinical Research and Perinatal Research Centre, The University of Queensland, Herston, Brisbane, Queensland 4029, Australia
Glia 58:181-94. 2010..Developing therapies that prevent or reverse these astrocytic changes may potentially improve neuronal survival and thus might be a useful strategy to minimize brain damage after an H/I insult... - Distribution of two splice variants of the glutamate transporter GLT-1 in rat brain and pituitaryPeter Reye
School of Biomedical Sciences, Department of Physiology and Pharmacology, University of Queensland, Brisbane, Australia
Glia 38:246-55. 2002.... - Distribution of two splice variants of the glutamate transporter GLT-1 in the developing rat retinaPeter Reye
Department of Physiology and Pharmacology, School of Biomedical Sciences, University of Queensland, Brisbane, Queensland 4072, Australia
J Comp Neurol 447:323-30. 2002.... - Rapid loss of glutamine synthetase from astrocytes in response to hypoxia: implications for excitotoxicityAven Lee
The University of Queensland, Centre for Clinical Research, Royal Brisbaneand Womens Hospital, Building 71 Herston, Brisbane, Queensland 4029, Australia
J Chem Neuroanat 39:211-20. 2010..Loss of GS from astrocytes would plausibly lead to a rise in intracellular glutamate, and could explain why reversal of astrocytic glutamate transport during hypoxia/ischaemia is conceptually possible... - Neuronal migration and glial remodeling in degenerating retinas of aged rats and in nonneovascular AMDRobert Sullivan
Department of Physiology and Pharmacology, School of Biomedical Sciences, University of Queensland, Brisbane, Australia
Invest Ophthalmol Vis Sci 44:856-65. 2003..To demonstrate structural and immunocytochemical changes associated with light-induced degeneration in albino rat retinas and human AMD retinas... - Astrocytes: Glutamate transport and alternate splicing of transportersAven Lee
The University of Queensland, Centre for Clinical Research, Queensland, Australia
Int J Biochem Cell Biol 42:1901-6. 2010..Such coordinate mechanisms may potentially contribute to changes in astrocyte function, especially in pathological contexts... - Morphological changes in white matter astrocytes in response to hypoxia/ischemia in the neonatal pigSusan M Sullivan
Centre for Clinical Research and Perinatal Research Centre, The University of Queensland, Herston, Brisbane, QLD, 4029, Australia
Brain Res 1319:164-74. 2010..These data suggest that astrocytes may contribute to the pathology of white matter damage following an H/I insult around the time of birth, and suggest that astrocytes may offer a novel target for therapies to improve outcomes after H/I... - Expression of multiple glutamate transporter splice variants in the rodent testisAven Lee
Centre for Clinical Research, Royal Brisbane and Women s Hospital, The University of Queensland, Brisbane, QLD 4029, Australia
Asian J Androl 13:254-65. 2011..The apparent presence of many of these transporters in the testis and sperm may indicate a need for glutamate transport by such cells... - MAP2 provides reliable early assessment of neural injury in the newborn piglet model of birth asphyxiaBarbara E Lingwood
Perinatal Research Centre, University of Queensland, Royal Brisbane and Women s Hospital, Herston, QLD 4029, Australia
J Neurosci Methods 171:140-6. 2008..Results indicate that MAP2 immunoreactivity 6h after hypoxia/ischaemia is a reliable marker of neural injury in the neonatal piglet... - The two-pore domain K+ channel TASK-1 is closely associated with brain barriers and meningesRefik Kanjhan
School of Biomedical Sciences, University of Queensland, Brisbane, QLD 4072, Australia
J Mol Histol 41:315-23. 2010..Our findings are likely to be relevant to recently reported roles of TASK-1 in cerebral ischemia, stroke and inflammatory brain disorders... - Antibody production and immunocytochemical localization of amino acid transportersDavid V Pow
Department of Physiology and Pharmacology, School of Biomedical Sciences, University of Queensland, Brisbane, Australia
Methods Mol Biol 227:213-44. 2003 - Exon 4-skipping GLT-1: a new form of an abundantly expressed glutamate transporterAven Lee
The University of Queensland, Centre for Clinical Research, Queensland, Australia
Neurosci Lett 504:228-31. 2011..We conclude that exon-4 skipping GLT 1 is abundantly expressed in the brain and may represent either a functional glutamate transporter or a modulator of glutamate transporter function... - Aberrant expression of the glutamate transporter excitatory amino acid transporter 1 (EAAT1) in Alzheimer's diseaseHeather L Scott
Departments of Biochemistry and Physiology and Pharmacology, University of Queensland, Brisbane, Queensland, Australia, 4072
J Neurosci 22:RC206. 2002..This study implicates aberrant glutamate transporter expression as a mechanism involved in neurodegeneration in Alzheimer's disease... - Retinal serotonin, eye growth and myopia development in chickAbigail George
Vision Touch and Hearing Research Centre, School of Biomedical Science, University of Queensland, Brisbane, QLD, Australia
Exp Eye Res 81:616-25. 2005..5%). Collectively, these results suggest that manipulations to the serotonin system can alter the eye growth process but the role of this transmitter system within this process remains unclear... - Localization of taurine transporters, taurine, and (3)H taurine accumulation in the rat retina, pituitary, and brainDavid V Pow
Department of Physiology and Pharmacology, School of Biomedical Sciences, University of Queensland, Brisbane, Australia
Glia 37:153-68. 2002..The heterogeneous distribution of taurine and its transporters in the brain does not reconcile well with the possibility that taurine acts solely as a ubiquitous osmolyte in nervous tissues...