Research Topics
Species | G C PattonSummaryAffiliation: University of Melbourne Country: Australia Publications
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Detail Information
Publications
A training agenda in adolescent medicine and healthSusan M Sawyer
Centre for Adolescent Health, Royal Children s Hospital, Victoria, Australia
Int J Adolesc Med Health 19:305-15. 2007..In Australia, this has been best achieved by centres of excellence in adolescent health...
Reverse gateways? Frequent cannabis use as a predictor of tobacco initiation and nicotine dependenceGeorge C Patton
Centre for Adolescent Health, Royal Children s Hospital, Murdoch Children s Research Institute and Department of Paediatrics, University of Melbourne, Victoria, Australia
Addiction 100:1518-25. 2005..Specifically we examined whether cannabis use in non-smokers predicted later initiation of tobacco use and whether cannabis use predicted later nicotine dependence in tobacco users...
The Gatehouse Project: a systematic approach to mental health promotion in secondary schoolsG C Patton
Centre for Adolescent Health, Royal Children s Hospital, Parkville, Victoria, Australia
Aust N Z J Psychiatry 34:586-93. 2000..The objective of this paper is to outline the conceptual background and strategy of intervention for a systematic and sustainable approach to mental health promotion in secondary schools...
Cannabis use and mental health in young people: cohort studyGeorge C Patton
Centre for Adolescent Health, Murdoch Children s Research Institute, Parkville, Victoria 3052, Australia
BMJ 325:1195-8. 2002..To determine whether cannabis use in adolescence predisposes to higher rates of depression and anxiety in young adulthood...
Adolescent medicineGeorge C Patton
Centre for Adolescent Health, Royal Children's Hospital, Parkville, VIC 3052
Med J Aust 176:3. 2002
Changing schools, changing health? Design and implementation of the Gatehouse ProjectGeorge Patton
Centre for Adolescent Health, Murdoch Childrens Research Institute, Victoria, Australia
J Adolesc Health 33:231-9. 2003..To describe the Gatehouse Project which addresses the social context of high school with an aim of changing students' sense of school connection and in turn, health risk behavior and well-being...
Adolescent depressive disorder: a population-based study of ICD-10 symptomsG C Patton
Department of Paediatrics, University of Melbourne, Australia
Aust N Z J Psychiatry 34:741-7. 2000..This study examines the frequency of ICD-10 symptoms in depressive disorder and their association with severity in a large community sample of adolescents aged 15 to 18 years...
Analysis of binary outcomes in longitudinal studies using weighted estimating equations and discrete-time survival methods: prevalence and incidence of smoking in an adolescent cohortJ B Carlin
Clinical Epidemiology and Biostatistics Unit, Royal Children s Hospital Research Institute and University of Melbourne, Department of Paediatrics, Royal Children s Hospital, Parkville, VIC 3052, Australia
Stat Med 18:2655-79. 1999..This approach has the advantages of providing estimates of relative risks, being feasible with standard software, and also allowing robust information-sandwich variance estimates...
Life events and early onset depression: cause or consequence?G C Patton
Murdoch Children's Research Institute, Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia
Psychol Med 33:1203-10. 2003..The association also reflects a reciprocal relationship in which earlier symptoms predict later events, perhaps as a result of an individual's attempts to change unfavourable social circumstances...
Onset of adolescent eating disorders: population based cohort study over 3 yearsG C Patton
Centre for Adolescent Health, Department of Paediatrics, University of Melbourne, Parkville Victoria 3052, Australia
BMJ 318:765-8. 1999..To study the predictors of new eating disorders in an adolescent cohort...
Parental 'affectionless control' in adolescent depressive disorderG C Patton
Department of Paediatrics, University of Melbourne, Victoria, Australia
Soc Psychiatry Psychiatr Epidemiol 36:475-80. 2001..Whether sub-optimal parenting is associated with a risk for the onset of depression outside the adolescent years has yet to be clarified...
Prospects for epigenetic research within cohort studies of psychological disorder: a pilot investigation of a peripheral cell marker of epigenetic risk for depressionC A Olsson
Murdoch Childrens Research Institute, Parkville 3052 Victoria, Australia
Biol Psychol 83:159-65. 2010..9, CI 1.9-13, p=0.001). Both complete and partial (as little as 10%) methylation of a 5HTT reporter gene in an expressing cell line reduced 5HTT activity. Replication is needed...
A role for the DRD4 exon III VNTR in modifying the association between nicotine dependence and neuroticismJ A Ellis
Environmental and Genetic Epidemiology Research, Murdoch Childrens Research Institute, Royal Children s Hospital, Parkville, Victoria 3052, Australia
Nicotine Tob Res 13:64-9. 2011....
Monitoring and care of young people at incipient risk of psychosisA R Yung
Early Psychosis Prevention and Intervention Centre, Parkville, Victoria, Australia
Schizophr Bull 22:283-303. 1996..Patients' needs, timing, and mode of treatment had to be considered. Preliminary data from the service's 20-month pilot phase are presented to help inform these issues...
The outcome of adolescent eating disorders: findings from the Victorian Adolescent Health Cohort StudyG C Patton
Centre for Adolescent Health, University of Melbourne, Parkville 3052, Australia
Eur Child Adolesc Psychiatry 12:I25-9. 2003..The findings are consistent with the partial syndrome of bulimia nervosa being viewed as a variant of affective disorder with different associated behaviours at particular developmental points...
Consequences of youth tobacco use: a review of prospective behavioural studiesM Mathers
Centre for Adolescent Health, Murdoch Childrens Research Institute and Department of Paediatrics, University of Melbourne, Australia
Addiction 101:948-58. 2006..Although health consequences from smoking have been documented, there has been a surprising lack of research into behavioural consequences...
COMT Val(158)Met and 5HTTLPR functional loci interact to predict persistence of anxiety across adolescence: results from the Victorian Adolescent Health Cohort StudyC A Olsson
Centre for Adolescent Health, Murdoch Childrens Research Institute, Royal Children s Hospital, The University of Melbourne, Parkville, Victoria, Australia
Genes Brain Behav 6:647-52. 2007....
Building capacity for system-level change in schools: lessons from the Gatehouse ProjectL Bond
Centre for Adolescent Health, Royal Children s Hospital, Parkville, Australia
Health Educ Behav 28:368-83. 2001..This article describes and accounts for how system-level changes have been made in schools through a process of capacity building. This encourages teachers, parents, and students to view the core business of education differently...
Youth alcohol and other drug use in the United States and Australia: a cross-national comparison of three state-wide samplesJ W Toumbourou
Centre for Adolescent Health, Murdoch Children's Research Institute, Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia
Drug Alcohol Rev 24:515-23. 2005..However, findings suggested that aspects of norm-violating substance use (substance use at school, marijuana use and other illicit drug use) were higher in the US states compared to Victoria...
Preventive interventions for youth suicide: a risk factor-based approachJ M Burns
Centre for Adolescent Health, Royal Children s Hospital, The University of Melbourne, Parkville, Victoria, Australia
Aust N Z J Psychiatry 34:388-407. 2000..Its goal is to identify areas of 'research need' and to provide an evidence base to identify 'best buy' preventive interventions for youth suicide...
Personality and substance use disorders in young adultsPaul Moran
Health Services Research Department, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Br J Psychiatry 188:374-9. 2006..There have been no studies of the co-occurrence of personality and substance use disorders in young community-dwelling adults...
Concern about tall stature during adolescence and depression in later lifeFiona J Bruinsma
Mother and Child Health Research, La Trobe University, 251 Faraday Street, Carlton VIC 3053, Australia
J Affect Disord 91:145-52. 2006..This retrospective cohort study aimed to examine the long-term psychosocial outcomes for women assessed or treated during adolescence for tall stature...
Promoting social inclusion in schools: a group-randomized trial of effects on student health risk behavior and well-beingGeorge C Patton
Centre for Adolescent Health and Murdoch Children s Research Institute, Melbourne, Australia
Am J Public Health 96:1582-7. 2006..We sought to test the efficacy of an intervention that was designed to promote social inclusion and commitment to education, in reducing among students health risk behaviors and improving emotional well-being...
Trajectories of adolescent alcohol and cannabis use into young adulthoodGeorge C Patton
Centre for Adolescent Health, Murdoch Children s Research Institute, Royal Children s Hospital, University of Melbourne Victoria, Australia
Addiction 102:607-15. 2007..Both are commonly initiated in adolescence. To date little research has described trajectories of adolescent cannabis or alcohol use or compared their respective consequences in young adulthood...
Teen smokers reach their mid twentiesGeorge C Patton
Centre for Adolescent Health, Royal Children s Hospital, Murdoch Childrens Research Institute, Parkville, Victoria, Australia
J Adolesc Health 39:214-20. 2006..Most outcome studies of adolescent smokers have focused on tobacco use in the short term. Few have reported on the health of adolescent smokers as they reach young adulthood...
Pubertal stage and deliberate self-harm in adolescentsGeorge C Patton
Centre for Adolescent Health, Murdoch Children s Research Institute and Department of Paediatrics, University of Melbourne, Austraia
J Am Acad Child Adolesc Psychiatry 46:508-14. 2007..To ascertain the association between pubertal stage and deliberate self-harm...
Problem alcohol use in young Australian adultsSophie C Reid
Centre for Adolescent Health, 2 Gatehouse Street, Parkville, VIC 3052, Australia
Aust N Z J Psychiatry 41:436-41. 2007..To examine the extent to which excessive drinking in young adults is associated with alcohol abuse and dependence...
The predictors and consequences of adolescent amphetamine use: findings from the Victoria Adolescent Health Cohort StudyLouisa Degenhardt
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia
Addiction 102:1076-84. 2007..However, little is known about the predictors and effects of early-onset amphetamine use. We set out to examine these issues using a representative cohort of young people followed-up over 11 years in Victoria, Australia...
Variation in the gene coding for the M5 muscarinic receptor (CHRM5) influences cigarette dose but is not associated with dependence to drugs of addiction: evidence from a prospective population based cohort study of young adultsRichard J L Anney
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
BMC Genet 8:46. 2007..We investigated whether these polymorphisms influence substance dependence and dose in a cohort of 1947 young Australians...
Who are the new amphetamine users? A 10-year prospective study of young AustraliansLouisa Degenhardt
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia
Addiction 102:1269-79. 2007..We examined these issues using a representative cohort of young people followed-up in Victoria, Australia...
Toward youth friendly services: a survey of young people in primary careDagmar M Haller
Centre for Adolescent Health, Murdoch Children s Institute at the Royal Children s Hospital, Melbourne, Australia
J Gen Intern Med 22:775-81. 2007..The World Health Organization encourages the development of youth friendly services, yet little is known on how youth currently present in general practice...
A comparison of self-reported puberty using the Pubertal Development Scale and the Sexual Maturation Scale in a school-based epidemiologic surveyLyndal Bond
Centre for Adolescent Health, Royal Children s Hospital, Murdoch Childrens Research Institute and Department of Paediatrics, University of Melbourne, 2 Gatehouse Street, Parkville 3052 VIC, Australia
J Adolesc 29:709-20. 2006..To examine concordance between two self-reported measures of puberty: Sexual Maturation Scale (SMS) and Pubertal Development Scale (PDS) and their acceptability to adolescents...
Cannabis dependence in young adults: an Australian population studyCarolyn Coffey
Centre for Adolescent Health, Murdoch Childrens Research Institute, Melbourne, Australia
Addiction 97:187-94. 2002....
Mental health of teenagers who use cannabis. Results of an Australian surveyJoseph M Rey
University of Sydney, Coral Tree Family Service, North Ryde, New South Wales, Australia
Br J Psychiatry 180:216-21. 2002..There is concern in the community about increasing cannabis use and its potential effect on health...
Transitions in an imperfectly observed binary variable: depressive symptomatology in adolescentsRory Wolfe
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
Stat Med 22:427-40. 2003..The motivation for this work comes from an analysis of transitions in depression status for a cohort of Australian teenagers participating in a longitudinal study of adolescent health...
Adolescent precursors of cannabis dependence: findings from the Victorian Adolescent Health Cohort StudyCarolyn Coffey
Murdoch Children s Research Institute, Parkville, Victoria, Australia
Br J Psychiatry 182:330-6. 2003..Dependence increases the likelihood of adverse consequences of cannabis use, but its aetiology is poorly understood...
Receipt of psychological or emotional counseling by suicidal adolescentsJane E Pirkis
Division of Adolescent Medicine, University of California San Francisco, San Francisco, California, USA
Pediatrics 111:e388-93. 2003..This study examined utilization of psychological or emotional counseling by suicidal adolescents to answer questions about the extent to which health services can contribute to the prevention of adolescent suicide...
Mortality in young offenders: retrospective cohort studyCarolyn Coffey
Centre for Adolescent Health, Murdoch Childrens Research Institute, Parkville, Victoria 3052, Australia
BMJ 326:1064. 2003..To estimate overall and cause specific standardised mortality ratios in young offenders...
Adolescent substance use: beware of international comparisonsJane E Pirkis
Division of Adolescent Medicine, University of California San Francisco, San Francisco, California, USA
J Adolesc Health 33:279-86. 2003..To compare prevalence estimates of adolescents' cigarette, alcohol and marijuana use from one Australian and two U.S. surveys, and to consider the effect of methodological differences on reported use...
Youth health research ethics: time for a mature-minor clause?Lena A Sanci
Department of General Practice, University of Melbourne, 200 Berkeley Street, Carlton, Victoria 3053, Australia
Med J Aust 180:336-8. 2004..There are grounds for considering a mature-minor clause in the National Health and Medical Research Council research ethics guidelines, particularly in the context of youth participation in minimal-risk research...
Nicotine dependence in a prospective population-based study of adolescents: the protective role of a functional tyrosine hydroxylase polymorphismRichard J L Anney
Behavioural Genetics Laboratory, Murdoch Childrens Research Institute, Royal Children s Hospital, University of Melbourne, Parkville, Melbourne, Australia
Pharmacogenetics 14:73-81. 2004..Including these data, three independent studies, two of which use identical phenotypes, have now identified a protective relationship between the K4 allele of the functional HUMTH01-VNTR polymorphism and high-level smoking...
Puberty and the onset of substance use and abuseGeorge C Patton
Centre for Adolescent Health, Murdoch Children s Research Institute and Department of Paediatrics, University of Melbourne, Melbourne, Australia
Pediatrics 114:e300-6. 2004..Substance abuse remains one of the major threats to adolescent health in Western cultures. The study aim was to ascertain the extent of association between pubertal development and early adolescent substance use...
Association between the COMT Val158Met polymorphism and propensity to anxiety in an Australian population-based longitudinal study of adolescent healthCraig A Olsson
Centre for Adolescent Health, Murdoch Children s Research Institute, Royal Children s Hospital, University of Melbourne, Victoria, Australia
Psychiatr Genet 15:109-15. 2005..Two recent reports have observed the association between the MetMet genotype and risk of anxiety in adult populations. We examined the association between the ValMet genotypes and propensity to anxiety across adolescence...
Confidential health care for adolescents: reconciling clinical evidence with family valuesLena A Sanci
Department of General Practice, University of Melbourne, Melbourne, Vic
Med J Aust 183:410-4. 2005..Evaluation of maturity must take into account characteristics of the young person, gravity of the proposed treatment, family factors, and statutory restrictions...
Predicting death in young offenders: a retrospective cohort studyCarolyn Coffey
Centre for Adolescent Health, Murdoch Children s Research Institute, 2 Gatehouse Street, Parkville, VIC 3052
Med J Aust 181:473-7. 2004..To examine predictors of death in young offenders who have received a custodial sentence using data routinely collected by juvenile justice services...
Teenage drinking and the onset of alcohol dependence: a cohort study over seven yearsYvonne A Bonomo
Centre for Adolescent Health, Murdoch Children s Research Institute
Addiction 99:1520-8. 2004..To determine whether adolescent alcohol use and/or other adolescent health risk behaviour predisposes to alcohol dependence in young adulthood...
Towards a national agenda for youth?George C Patton
Med J Aust 183:394-5. 2005
Heavy cannabis use and depressive symptoms in three Aboriginal communities in Arnhem Land, Northern TerritoryK S Kylie Lee
School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Cairns, QLD, Australia
Med J Aust 188:605-8. 2008..To determine the extent to which depressive symptoms are associated with heavy cannabis use in an Aboriginal population in Arnhem Land, Northern Territory...
Parental smoking and smoking experimentation in childhood increase the risk of being a smoker 20 years later: the Childhood Determinants of Adult Health StudySeana L Paul
Menzies Research Institute, University of Tasmania, Australia
Addiction 103:846-53. 2008..To examine the long-term effects of childhood smoking experimentation and exposure to parental smoking on adult smoking risk...
Are diagnostic orphans at risk of developing cannabis abuse or dependence? Four-year follow-up of young adult cannabis users not meeting diagnostic criteriaLouisa Degenhardt
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia
Drug Alcohol Depend 92:86-90. 2008..To examine the characteristics of "diagnostic orphans" among cannabis users - those who report one or two symptoms of DSM-IV dependence but do not meet diagnostic criteria for DSM-IV abuse or dependence - 4 years post-assessment...
Prematurity at birth and adolescent depressive disorderGeorge C Patton
Murdoch Children s Research Institute, Centre for Adolescent Health, Parkville, Victoria, Australia
Br J Psychiatry 184:446-7. 2004..2% (95% CI 11.1-20.5) v. 1.8% (95% CI 1.6-2.1) in those with normal deliveries. Physiological adaptations in utero before full term may be implicated causally in some cases of depression in adolescence...
Prevalence of substance use and delinquent behavior in adolescents from Victoria, Australia and Washington State, United StatesBarbara J McMorris
University of Washington, Seattle, USA
Health Educ Behav 34:634-50. 2007..Implications for conducting international comparisons are discussed...
Service responses for youth onset mental disordersGeorge C Patton
Centre for Adolescent Health, Murdoch Childrens Research Institute, Royal Children s Hospital, University of Melbourne, Australia
Curr Opin Psychiatry 20:319-24. 2007..We summarize recent work indicating where interventions are most needed and effective. We also review the literature that examines the scope for reorienting mental health services to meet the needs of adolescents and young adults...
A picture of Australia's childrenGeorge C Patton
Med J Aust 182:437-8. 2005..Do we have a clear enough picture to guide rational health and social policy responses?..
Pubertal transitions in healthGeorge C Patton
Murdoch Childrens Research Institute, Department of Paediatrics, University of Melbourne, Melbourne, Australia
Lancet 369:1130-9. 2007..Recent secular trends in these psychosocial disorders coincide with a growing mismatch between biological and social maturation, and the emergence of more dominant youth cultures...
Practical evidence in favour of mature-minor consent in primary care researchDagmar M Haller
Med J Aust 183:439. 2005
