Steven E Mutsaers

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi The mesothelial cell
    Steven E Mutsaers
    Department of Surgery, University of Western Australia, Royal Perth Hospital, Perth 6000, WA, Australia
    Int J Biochem Cell Biol 36:9-16. 2004
  2. ncbi Stimulation of mesothelial cell proliferation by exudate macrophages enhances serosal wound healing in a murine model
    Steven E Mutsaers
    Department of Pathology, University of Western Australia, Level 2 Medical Research Foundation Building, Rear 50 Murray St, Perth, 6000, Western Australia
    Am J Pathol 160:681-92. 2002
  3. ncbi The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?
    Darryl A Knight
    Asthma and Allergy Research Institute, Sir Charles Gairdner Hospital, Ground Floor, E Block, Verdun Street, Nedlands, Western Australia, 6009, Australia
    Pharmacol Ther 99:327-38. 2003
  4. ncbi Growth factors in pleural fibrosis
    Steven E Mutsaers
    Asthma, Allergy and Respiratory Research Institute, Department of Medicine, University of Western Australia, Perth, Australia
    Curr Opin Pulm Med 12:251-8. 2006
  5. ncbi Mesothelial cell differentiation into osteoblast- and adipocyte-like cells
    Sally M Lansley
    Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, WA, Australia
    J Cell Mol Med 15:2095-105. 2011
  6. ncbi Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia
    Cecilia M Prele
    School of Anatomy and Human Biology, University of Western Australia, Crawley, Perth 6009, Australia
    Cardiovasc Pathol 21:17-27. 2012
  7. ncbi Mesothelial cells: their structure, function and role in serosal repair
    Steven E Mutsaers
    Asthma and Allergy Research Institute and Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Respirology 7:171-91. 2002
  8. ncbi Pathogenesis of pleural fibrosis
    Steven E Mutsaers
    Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, Australia
    Respirology 9:428-40. 2004
  9. ncbi Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation
    Yuben P Moodley
    Asthma and Allergy Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Am J Pathol 163:345-54. 2003
  10. ncbi Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis
    Felix Chua
    Department of Medicine, Royal Free and University College Medical School, London United Kingdom
    Am J Pathol 170:65-74. 2007

Collaborators

Detail Information

Publications12

  1. ncbi The mesothelial cell
    Steven E Mutsaers
    Department of Surgery, University of Western Australia, Royal Perth Hospital, Perth 6000, WA, Australia
    Int J Biochem Cell Biol 36:9-16. 2004
    ..Although closely associated with exposure to asbestos, recent studies have implicated other factors including simian virus 40 (SV40) in its pathogenesis...
  2. ncbi Stimulation of mesothelial cell proliferation by exudate macrophages enhances serosal wound healing in a murine model
    Steven E Mutsaers
    Department of Pathology, University of Western Australia, Level 2 Medical Research Foundation Building, Rear 50 Murray St, Perth, 6000, Western Australia
    Am J Pathol 160:681-92. 2002
    ..These data support the hypothesis that macrophages play an important role in serosal healing by stimulating mesothelial cell proliferation...
  3. ncbi The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?
    Darryl A Knight
    Asthma and Allergy Research Institute, Sir Charles Gairdner Hospital, Ground Floor, E Block, Verdun Street, Nedlands, Western Australia, 6009, Australia
    Pharmacol Ther 99:327-38. 2003
    ..This may provide guides for the development of novel pharmacological treatment for fibroproliferative diseases...
  4. ncbi Growth factors in pleural fibrosis
    Steven E Mutsaers
    Asthma, Allergy and Respiratory Research Institute, Department of Medicine, University of Western Australia, Perth, Australia
    Curr Opin Pulm Med 12:251-8. 2006
    ..Understanding the biology of these growth factors may allow therapeutic manipulation of these cytokines to create pleurodesis or to inhibit pleural (and peritoneal) adhesion/fibrosis...
  5. ncbi Mesothelial cell differentiation into osteoblast- and adipocyte-like cells
    Sally M Lansley
    Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, WA, Australia
    J Cell Mol Med 15:2095-105. 2011
    ..These data strongly support mesothelial cell differentiation as the potential source of different tissue types in MM tumours and other serosal pathologies, and add support for the use of mesothelial cells in regenerative therapies...
  6. ncbi Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia
    Cecilia M Prele
    School of Anatomy and Human Biology, University of Western Australia, Crawley, Perth 6009, Australia
    Cardiovasc Pathol 21:17-27. 2012
    ..The aim of the present study was to assess the structural and ex vivo functional impacts of long-term cardiomyocyte-specific insulin-like growth factor-1 overexpression in hearts of transgenic ?MHC-IGF-1 Ea mice...
  7. ncbi Mesothelial cells: their structure, function and role in serosal repair
    Steven E Mutsaers
    Asthma and Allergy Research Institute and Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Respirology 7:171-91. 2002
    ..In the present review, the current understanding of the structure and function of the mesothelium and the biology of mesothelial cells is discussed, together with recent insights into the mechanisms regulating its repair...
  8. ncbi Pathogenesis of pleural fibrosis
    Steven E Mutsaers
    Centre for Asthma, Allergy and Respiratory Research, University of Western Australia, Australia
    Respirology 9:428-40. 2004
    ....
  9. ncbi Fibroblasts isolated from normal lungs and those with idiopathic pulmonary fibrosis differ in interleukin-6/gp130-mediated cell signaling and proliferation
    Yuben P Moodley
    Asthma and Allergy Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Am J Pathol 163:345-54. 2003
    ..IL-11 was mitogenic for both normal and IPF fibroblasts. These results provide strong evidence for a fundamental abnormality in a cytokine-signaling pathway, as opposed to alterations in cytokine production, in the pathogenesis of IPF...
  10. ncbi Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis
    Felix Chua
    Department of Medicine, Royal Free and University College Medical School, London United Kingdom
    Am J Pathol 170:65-74. 2007
    ..These data point to novel and unexpected fibrogenic consequences of neutrophil elastase activity in the inflamed lung...
  11. ncbi Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing
    Adam J Foley-Comer
    Department of Medicine, Royal Free and University College Medical School, The Rayne Institute, London, WC1E 6JJ, UK
    J Cell Sci 115:1383-9. 2002
    ..This study has clearly shown that serosal healing involves implantation, proliferation and incorporation of free-floating mesothelial cells into the regenerating mesothelium...
  12. ncbi Mesothelial progenitor cells and their potential in tissue engineering
    Sarah E Herrick
    School of Biological Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Int J Biochem Cell Biol 36:621-42. 2004
    ..However, only by performing detailed investigations involving selective cell isolation, clonal analysis together with cell labelling and tracking studies, will we begin to determine the true existence of a mesothelial stem cell...