Research Topics
| Vaughan G MacefieldSummaryAffiliation: University of Western Sydney Country: Australia Publications
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Publications
Developments in autonomic research: a review of the latest literatureVaughan G Macefield
School of Medicine, University of Western Sydney, Locked Bag 1797, Penrith South DC, NSW, 1797, Australia
Clin Auton Res 19:133-6. 2009..Given that the nucleus accumbens forms part of the reward circuitry, it is perhaps not surprising that it is activated during that most pleasurable of autonomic acts, orgasm...- Firing properties of sudomotor neurones in hyperhidrosis and thermal sweatingVaughan G Macefield
Prince of Wales Medical Research Institute, Sydney, Australia
Clin Auton Res 18:325-30. 2008.... - Can loss of muscle spindle afferents explain the ataxic gait in Riley-Day syndrome?Vaughan G Macefield
School of Medicine, University of Western Sydney, Locked Bag 1797, Penrith, Sydney NSW 2751, Australia
Brain 134:3198-208. 2011..Moreover, we suggest that their ataxic gait is sensory in origin, due to the loss of functional muscle spindles and hence a compromised sensorimotor control of locomotion... - Developments in autonomic research: a review of the latest literatureVaughan G Macefield
School of Medicine, University of Western Sydney, Penrith South DC, NSW 1797, Australia
Clin Auton Res 19:193-6. 2009.... - Real-time imaging of the medullary circuitry involved in the generation of spontaneous muscle sympathetic nerve activity in awake subjectsVaughan G Macefield
School of Medicine, University of Western Sydney, and Prince of Wales Medical Research Institute, Sydney, Australia
Hum Brain Mapp 31:539-49. 2010.... - Axonal changes in spinal cord injured patients distal to the site of injuryCindy Shin Yi Lin
Prince of Wales Medical Research Institute and Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
Brain 130:985-94. 2007..Changes in axonal structure and ion channel function, but perhaps more critically decentralization and consequent inactivity, are likely to underlie the complex changes observed in axonal excitability in SCI patients... - Gender differences in brain activity evoked by muscle and cutaneous pain: a retrospective study of single-trial fMRI dataLuke A Henderson
Department of Anatomy and Histology, University of Sydney, Sydney, NSW, Australia
Neuroimage 39:1867-76. 2008..These differences may reflect differences in emotional processing of noxious information in men and women and may underlie the gender bias that exists in many chronic pain conditions... - Mechanically evoked sensory and motor responses to dynamic compression of the ulnar nerveElizabeth C Clarke
School of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, Sydney, Australia
Muscle Nerve 35:303-11. 2007..Cutaneous axons had lower mechanical thresholds than motor axons. We relate these findings to the viscoelastic properties of peripheral nerves and differences in biophysical properties of cutaneous and motor axons... - Slowly adapting mechanoreceptors in the borders of the human fingernail encode fingertip forcesIngvars Birznieks
Prince of Wales Medical Research Institute, Sydney, New South Wales 2031, Australia
J Neurosci 29:9370-9. 2009..The particular tactile features of contacted surfaces would less influence force-related signals in SA-IInail afferents than force-related signals present in afferents terminating in the volar skin areas that directly contact objects... - Evidence for strong synaptic coupling between single tactile afferents from the sole of the foot and motoneurons supplying leg musclesJames B Fallon
Prince of Wales Medical Research Institute, Sydney, New South Wales, Australia
J Neurophysiol 94:3795-804. 2005.... - Changes in the spatiotemporal expression of local and referred pain following repeated intramuscular injections of hypertonic saline: a longitudinal studyTroy K Rubin
Prince of Wales Medical Research Institute, Sydney, NSW, Australia
J Pain 11:737-45. 2010.... - Intraneural microstimulation of motor axons in the study of human single motor unitsPenelope A McNulty
Prince of Wales Medical Research Institute and University of New South Wales, Sydney, NSW, Australia
Muscle Nerve 32:119-39. 2005.... - Vibration sensitivity of human muscle spindles and Golgi tendon organsJames B Fallon
Prince of Wales Medical Research Institute, Sydney, NSW, Australia
Muscle Nerve 36:21-9. 2007.... - Vestibular and pulse-related modulation of skin sympathetic nerve activity during sinusoidal galvanic vestibular stimulation in human subjectsCheree James
School of Medicine, University of Western Sydney, Locked Bag 1797, Penrith South DC, NSW 1797, Australia
Exp Brain Res 202:291-8. 2010..3 +/- 8.3%), the opposite of the pattern seen with vestibular modulation of MSNA. We conclude that vestibular inputs can entrain the firing of cutaneous sympathetic neurones and increase their normally weak pulse-related rhythmicity... - Frequency-dependent modulation of muscle sympathetic nerve activity by sinusoidal galvanic vestibular stimulation in human subjectsTarandeep Grewal
School of Medicine, University of Western Sydney, Locked Bag 1797, Penrith South DC, Sydney, NSW, 1797, Australia
Exp Brain Res 197:379-86. 2009..8 Hz), with vestibular modulation of MSNA being greater when this competition with the baroreceptors is reduced... - Comparison of the firing patterns of human postganglionic sympathetic neurones and spinal alpha motoneurones during brief burstsVaughan G Macefield
Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
Exp Physiol 89:82-8. 2004.... - Input-output relationships of a somatosympathetic reflex in human spinal injuryRachael Brown
Spinal Injuries Research Centre, Prince of Wales Medical Research Institute, Sydney, NSW 2031, Australia
Clin Auton Res 19:213-20. 2009.... - Firing probability and mean firing rates of human muscle vasoconstrictor neurones are elevated during chronic asphyxiaCynthia Ashley
Prince of Wales Medical Research Institute, Sydney, Australia
J Physiol 588:701-12. 2010.... - The effects of experimental muscle and skin pain on the static stretch sensitivity of human muscle spindles in relaxed leg musclesIngvars Birznieks
Prince of Wales Medical Research Institute, Barker Street, Randwick, NSW 2031, Sydney, Australia
J Physiol 586:2713-23. 2008..Rather, our results are more aligned with the pain adaptation model, based on clinical studies predicting pain-induced reductions of agonist muscle activity... - Resting discharge of human muscle spindles is not modulated by increases in sympathetic driveVaughan G Macefield
Prince of Wales Medical Research Institute and University of New South Wales, Sydney, Australia
J Physiol 551:1005-11. 2003.... - Effects of intramuscular anesthesia on the expression of primary and referred pain induced by intramuscular injection of hypertonic salineTroy K Rubin
Prince of Wales Medical Research Institute, Sydney NSW, Australia
J Pain 10:829-35. 2009..It is important to know the primary source of the pain so that treatment can be directed to this site rather to the site of referral... - Prolonged surges of baroreflex-resistant muscle sympathetic drive during periodic breathingVaughan G Macefield
Prince of Wales Medical Research Institute, Randwick, NSW, Australia
Clin Auton Res 12:165-9. 2002.... - Cardiovascular and respiratory modulation of tactile afferents in the human finger padVaughan G Macefield
Prince of Wales Medical Research Institute and University of New South Wales, Sydney, NSW 2052, Australia
Exp Physiol 88:617-25. 2003..It is concluded that cardiac modulation is common for both classes of slowly adapting tactile afferents (but less common for the rapidly adapting afferents), which may have implications for the sensory signalling of tactile information... - Within-limb somatotopic representation of acute muscle pain in the human contralateral dorsal posterior insulaLuke A Henderson
Department of Anatomy and Histology, University of Sydney, Sydney, New South Wales 2006, Australia
Hum Brain Mapp 32:1592-601. 2011..Shoulder pain was represented anterior to forearm pain and medial to hand pain. This fine somatotopic organization may be crucial for pain localization or other aspects of the pain experience that differ depending on stimulation site... - Respiratory modulation of muscle sympathetic nerve activity is not increased in essential hypertension or chronic obstructive pulmonary diseaseRania Fatouleh
School of Medicine, University of Western Sydney, Sydney, Australia
J Physiol 589:4997-5006. 2011..Moreover, given that patients with COPD are chronically asphyxic, these data indicate that an increased chemical drive does not increase respiratory modulation of MSNA... - Physiological characteristics of low-threshold mechanoreceptors in joints, muscle and skin in human subjectsVaughan G Macefield
Prince of Wales Medical Research Institute and University of New South Wales, Sydney, New South Wales, Australia
Clin Exp Pharmacol Physiol 32:135-44. 2005.... - Discrete changes in cortical activation during experimentally induced referred muscle pain: a single-trial fMRI studyVaughan G Macefield
Prince of Wales Medical Research Institute and the University of New South Wales, Sydney, NSW, Australia
Cereb Cortex 17:2050-9. 2007..Interestingly, differential signal changes also occurred in anterior cingulate, cerebellar, and insular cortices. This is the first study to provide evidence of cortical differentiation in the processing of primary and referred pain... - Competitive interactions between vestibular and cardiac rhythms in the modulation of muscle sympathetic nerve activityCheree James
School of Medicine, University of Western Sydney, Sydney, Australia
Auton Neurosci 158:127-31. 2010..3±3.3%) than this frequency. We conclude that vestibular inputs compete with baroreceptor inputs operating at the cardiac rhythm, with vestibular modulation of MSNA being lowest when competition with the baroreceptors is highest... - Firing properties of single postganglionic sympathetic neurones recorded in awake human subjectsVaughan G Macefield
Prince of Wales Medical Research Institute, NSW, Sydney, Australia
Auton Neurosci 95:146-59. 2002..In this review, we describe our methodology for analyzing unitary sympathetic activity and discuss the similarities in the firing properties of individual muscle vasoconstrictor, cutaneous vasoconstrictor and sudomotor neurones... - Modulation of human muscle spindle discharge by arterial pulsations - functional effects and consequencesIngvars Birznieks
School of Science and Health, University of Western Sydney, Sydney, New South Wales, Australia
PLoS ONE 7:e35091. 2012.... - Allodynia mediated by C-tactile afferents in human hairy skinSaad S Nagi
School of Medicine, University of Western Sydney, Sydney NSW, Australia
J Physiol 589:4065-75. 2011..These results demonstrate that CT fibres in hairy skin mediate allodynia, and that CT-mediated inputs have a pluripotent central effect... - Low-frequency sinusoidal galvanic stimulation of the left and right vestibular nerves reveals two peaks of modulation in muscle sympathetic nerve activityElie Hammam
School of Medicine, University of Western Sydney, Penrith, Sydney, NSW 2751, Australia
Exp Brain Res 213:507-14. 2011.... - Loads applied tangential to a fingertip during an object restraint task can trigger short-latency as well as long-latency EMG responses in hand musclesVaughan G Macefield
Prince of Wales Medical Research Institute, UNSW, Barker St, Randwick, Sydney, NSW 2031, Australia
Exp Brain Res 152:143-9. 2003....