Research Topics
Genomes and GenesSpecies | Daniel R GettsSummaryAffiliation: University of Sydney Country: Australia Publications
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Detail Information
Publications
Viruses and the immune system: their roles in seizure cascade developmentDaniel R Getts
The Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney, New South Wales, Australia
J Neurochem 104:1167-76. 2008....
Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitisDaniel R Getts
The Discipline of Pathology, School of Medical Sciences, The University of Sydney, Sydney NSW 2006, Australia
J Exp Med 205:2319-37. 2008..Therefore, CCL2-dependent inflammatory monocyte migration is critical for increases in microglia during WNV infection and may also play a pathogenic role during WNV encephalitis...
Role of IFN-gamma in an experimental murine model of West Nile virus-induced seizuresDaniel R Getts
The Discipline of Pathology, The University of Sydney, Sydney, New South Wales, Australia
J Neurochem 103:1019-30. 2007..Our data show that IFN-gamma plays an important role in the development of the excitatory seizure pathways in the brain and that these cascades become pathogenic in encephalitic WNV infection...
Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitisAlbert Quintana
School of Molecular and Microbial Biosciences, University of Sydney, New South Wales, Australia
J Immunol 183:2079-88. 2009....
CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous systemMarcus Müller
School of Molecular and Microbial Biosciences, School of Medical Sciences, University of Sydney, Sydney, Australia
J Immunol 179:2774-86. 2007..We conclude that in EAE, CXCR3 signaling constrains T cells to the perivascular space in the CNS and augments regulatory T cell recruitment and effector T cell interaction, thus limiting autoimmune-mediated tissue damage...
Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct virusesChristie Wacher
School of Molecular and Microbial Biosciences, University of Sydney, Sydney, NSW 2006, Australia
J Virol 81:860-71. 2007..These findings suggest a dominant role for the ISG-49, ISG-54, and ISG-56 genes in the host response to different viruses in the central nervous system, where, particularly in neurons, these genes may have nonredundant functions...
Immunopathology of flavivirus infectionsNicholas J C King
Department of Pathology, School of Medical Sciences, Bosch Institute, The University of Sydney, Sydney, New South Wales, Australia
Immunol Cell Biol 85:33-42. 2007....
