Research Topics
| M J EadieSummaryAffiliation: University of Queensland Country: Australia Publications
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Detail Information
Publications
Clinically significant drug interactions with agents specific for migraine attacksM J Eadie
Department of Medicine, University of Queensland, Royal Brisbane Hospital, Australia
CNS Drugs 15:105-18. 2001..In contrast, new interactions involving the triptans are likely to be recognised as additional members of this family of drugs, with their different patterns of metabolism and pharmacokinetics, are marketed...
Could valerian have been the first anticonvulsant?Mervyn J Eadie
Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
Epilepsia 45:1338-43. 2004..To assess the available evidence for the belief that valerian, highly recommended in the past for treating epilepsy, possessed real anticonvulsant effectiveness...
Alfred Walter Campbell (1868-1937)M J Eadie
University of Queensland Ladhope Chambers 131 Wickham Terrace Brisbane 400, Australia
J Neurol 250:249-50. 2003
The antiepileptic Materia Medica of Pediacus DioscoridesM J Eadie
Department of Medicine, University of Queensland, Herston, Brisbane 4029, Australia
J Clin Neurosci 11:697-701. 2004..The stones, or one of them, were worn against the skin of the seizure sufferer. The use of the swallow stones for epilepsy was recommended as late as in the writings of Thomas Willis (1675)...
The epileptology of Théodore Herpin (1799-1865)Mervyn J Eadie
Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
Epilepsia 43:1256-61. 2002....
A.W. Campbell's Australian career: 1905-1937M J Eadie
University of Medicine, University of Queensland, Brisbane, Australia
J Clin Neurosci 8:514-9. 2001..Campbell's circumstances in Sydney, his extremely reticent nature and the essentially negative outcome of his investigation probably explain his failure to make his study more widely known...
The pathogenesis of migraine - 17th to early 20th century understandingsM J Eadie
Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
J Clin Neurosci 12:383-8. 2005..No hypothesis has yet proved capable of explaining all the features of migraine satisfactorily...
The epileptology of William Aldren TurnerM J Eadie
Department of Medicine, University of Queensland, Brisbane, Queensland, Australia
J Clin Neurosci 13:9-13. 2006....
Ergot of rye-the first specific for migraineM J Eadie
Department of Medicine, University of Queensland, Brisbane, Australia
J Clin Neurosci 11:4-7. 2004....
Cortical epileptogenesis--Hughlings Jackson and his predecessorsMervyn J Eadie
Department of Medicine Royal Brisbane Hospital, Central Clinical School, University of Queensland, Brisbane, Australia
Epilepsia 48:2010-5. 2007..To trace the concept that the cerebral cortex is the site of epileptogenesis before Hughlings Jackson published the idea in 1870 in the paper "A study of convulsions" which marks the beginning of modern epileptology...
Effect of naproxen co-administration on valproate dispositionR S Addison
Centre for Studies in Drug Disposition, The University of Queensland, Clinical Sciences Building, Royal Brisbane Hospital, Queensland, Australia
Biopharm Drug Dispos 21:235-42. 2000....
The role of focal epilepsy in the development of jacksonian localizationM J Eadie
Department of Medicine, University of Queensland, Brisbane, Australia
J Hist Neurosci 18:262-82. 2009....
Anticonvulsant therapy in aged patients. Clinical pharmacokinetic considerationsI Bernus
Conjoint Endocrine Laboratory, Royal Brisbane Hospital, Queensland, Australia
Drugs Aging 10:278-89. 1997..Thus. the clearances of vigabatrin and gabapentin correlate with creatinine clearance. Such considerations may help guide anticonvulsant dosage in the elderly...
Plasma antiepileptic drug concentrations during pregnancyC M Lander
Department of Neurology, Royal Brisbane Hospital, Herston, Australia
Epilepsia 32:257-66. 1991..This may have occurred because some patients were seen too late in their pregnancies for the policy to have been applied optimally...
A pathology of the animal spirits -- the clinical neurology of Thomas Willis (1621-1675). Part II -- disorders of intrinsically abnormal animal spiritsM J Eadie
Department of Medicine, University of Queensland, Brisbane, Australia
J Clin Neurosci 10:146-57. 2003....
Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancyFrank J Vajda
Department of Medicine, The Australian Centre For Neuropharmacology, Raoul Wallenberg Centre, St Vincent s Hospital, Fitzroy, 3065 Melbourne, Vic, Australia
J Clin Neurosci 11:854-8. 2004..A prospective, observational, community-based cohort study...
Absinthe, epileptic seizures and Valentin MagnanM J Eadie
University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Australia
J R Coll Physicians Edinb 39:73-8. 2009..Whether that component, presumably thujone, was present at convulsant concentrations in some of the available absinthes of Magnan's time cannot now be known...
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significanceM J Eadie
Department of Medicine, University of Queensland, Brisbane, Australia
Clin Pharmacokinet 21:27-41. 1991....
Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteersR S Addison
Centre for Studies in Drug Disposition, The University of Queensland, Royal Brisbane Hospital, Australia
Eur J Clin Pharmacol 56:715-21. 2000....
Utilization of anti-Parkinson drugs in Australia: 1995-2009Samantha A Hollingworth
The University of Queensland, School of Population Health, Herston, Australia
Pharmacoepidemiol Drug Saf 20:450-6. 2011..To examine trends in the prescribing of anti-Parkinsonian drugs (APD) in Australia from 1995 to 2009...
The idea of epilepsy as a disease per seMervyn J Eadie
Central Clinical School University of Queensland, Royal Brisbane and Women s Hospital, Herston, Australia 4027
J Hist Neurosci 19:209-20. 2010..With increasing identification of structural brain pathology in what had been regarded as instances of idiopathic epilepsy, the latter view has increasingly prevailed...
Antiepileptic drugs in Australia: 2002-2007Samantha A Hollingworth
School of Population Health, University of Queensland, Herston, QLD 4006, Australia
Pharmacoepidemiol Drug Saf 19:82-9. 2010..We examined the trends in the prescribing of subsidised AEDs in the Australian population from 2002 to 2007...
Experimental epileptology before 1900Mervyn J Eadie
Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
Epilepsia 50:377-386. 2009..Nevertheless, the pre-1900 investigations not only laid the foundations for the 20th Century expansion of experimental studies on epileptogenesis but also advanced the understanding of epileptic seizure production...
Samuel Wilks (1824-1911): neurologist and generalist of the Mid-Victorian EraMervyn J Eadie
Department of Medicine, Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
J Med Biogr 16:215-20. 2008..He provided possibly the first account of alcoholic peripheral neuritis and published an early account of probable myasthenia gravis...
Antiepileptic drugs as human teratogensMervyn J Eadie
University of Queensland, and Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia 4029, Australia
Expert Opin Drug Saf 7:195-209. 2008..There is still uncertainty concerning the risk of fetal malformation associated with the intake of various individual antiepileptic drugs in pregnant women...
Rigor mortis and the epileptology of Charles Bland Radcliffe (1822-1889)M J Eadie
Central Clinical School, University of Queensland, Royal Brisbane Hospital, Herston, Herston Road, Brisbane, 4027, Australia
J Clin Neurosci 14:201-7. 2007..As well, Radcliffe was one of the chief early advocates for potassium bromide, the first effective anticonvulsant...
The neurological legacy of John Russell Reynolds (1828-1896)M J Eadie
Central Clinical School, University of Queensland, Royal Brisbane Hospital, Brisbane, Herston, 4029, Queensland, Australia
J Clin Neurosci 14:309-16. 2007....
James Ross (1837-1892) and his forgotten neurology textbook of 1881M J Eadie
Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Australia
J R Coll Physicians Edinb 40:263-8. 2010....
The effect of body size on the metabolic clearance of carbamazepineD M Reith
Royal Children s Hospital, Herston Rd, Herston, Queensland, Australia
Biopharm Drug Dispos 21:103-11. 2000..To examine the profile of the known pathways of carbamazepine (CBZ) metabolism in a group of children and adolescents, and to test for associations with physical measurements, age and plasma hormonal levels...
Convulsive ergotism: epidemics of the serotonin syndrome?Mervyn J Eadie
Department of Medicine, University of Queensland, and the Royal Brisbane Hospital, Brisbane, Australia
Lancet Neurol 2:429-34. 2003..The serotonin syndrome may, therefore, have been a public-health problem long before it was recognised as a complication of modern psychopharmacology...
Hubert Airy, contemporary men of science and the migraine auraM J Eadie
Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Australia
J R Coll Physicians Edinb 39:263-7. 2009..Subsequently, migraine with aura quickly became a well-recognised clinical entity in British medicine...
The single seizure. To treat or not to treat?M J Eadie
Department of Clinical Neurology and Neuropharmacology, University of Queensland, Brisbane, Australia
Drugs 54:651-6. 1997..Unless a further seizure would hold little disadvantage, early treatment probably offers distinctly more benefit than hazard. No data are available to indicate the most appropriate duration of therapy after a single seizure...
Can anticonvulsant drug therapy "cure" epilepsy?M J Eadie
Department of Medicine, University of Queensland, 131 Wickham Tce, Brisbane, Queensland 4000, Australia
CNS Drugs 15:679-90. 2001..Therefore it would appear premature to take the view that contemporary anticonvulsant drug therapy does no more than suppress epileptic seizures until epilepsy remits spontaneously, or fails to remit, with the passing of time...
Therapeutic drug monitoring--antiepileptic drugsM J Eadie
Department of Medicine, University of Queensland, Brisbane, Australia
Br J Clin Pharmacol 52:11S-20S. 2001....
Marshall Hall, the reflex arc and epilepsyM J Eadie
Central Clinical School, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
J R Coll Physicians Edinb 38:167-71. 2008..However, from 1870 onwards it was superseded by John Hughlings Jackson's accumulating evidence that epileptic seizures often arose in the cerebral cortex...
Urinary excretion of valproate metabolites in children and adolescentsD M Reith
Royal Children s Hospital, Brisbane, Queensland 4029, Australia
Biopharm Drug Dispos 21:327-30. 2000..001 versus p<0.05). In conclusion, older children and adolescents, when compared with younger children, and those comedicated with LTG excrete a higher proportion of VPA dose as VPA-glucuronide...
A pathology of the animal spirits -- the clinical neurology of Thomas Willis (1621-1675) part I -- background, and disorders of intrinsically normal animal spiritsM J Eadie
Department of Medicine, University of Queensland
J Clin Neurosci 10:14-29. 2003..The disorders he attributed to inherently abnormal animal spirits are considered in a second part of the paper...
Victor Horsley's contribution to Jacksonian epileptologyMervyn J Eadie
Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
Epilepsia 46:1836-40. 2005..CONCLUSIONS: On the basis of well-designed experiments, Horsley made a major contribution to the understanding of epileptic seizure propagation mechanisms...
Monitoring salivary lamotrigine concentrationsStephen A Malone
Royal Children's Hospital, Brisbane, Queensland, Australia
J Clin Neurosci 13:902-7. 2006..This has significant implications for the elucidation of the pharmacokinetics of lamotrigine in the paediatric population...
Withdrawal of methylphenobarbitoneMervyn J Eadie
Med J Aust 178:44. 2003
