Research Topics
| J R DuncanSummaryAffiliation: University of Melbourne Country: Australia Publications
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Detail Information
Publications
White matter injury after repeated endotoxin exposure in the preterm ovine fetusJhodie R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, Victoria, Australia
Pediatr Res 52:941-9. 2002..Thus, repeated exposure of the preterm ovine fetus to LPS causes neuropathology resembling that of cerebral palsy and provides a robust model for exploring the etiology, prevention, and treatment of white matter damage...
The effects of repeated endotoxin exposure on placental structure in sheepJ R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, 3010, Victoria, Australia
Placenta 24:786-9. 2003..We conclude that repeated endotoxin exposure results in damage to the placenta which could lead to persistent alterations in placental exchange function...
Effects of umbilical cord occlusion in late gestation on the ovine fetal brain and retinaJhodie R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Australia
J Soc Gynecol Investig 11:369-76. 2004..Our aim was to assess quantitatively the persistent consequences of UCO on the developing brain; we also examined the retina...
Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiencyTodd A Briscoe
Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia
Am J Obstet Gynecol 191:847-55. 2004..The aim of this study was to determine the long-term effects of chronic placental insufficiency on the metabolic state and organ structure in the fetal and adolescent guinea pig...
Neurotrophin expression in the hippocampus and cerebellum is affected by chronic placental insufficiency in the late gestational ovine fetusJhodie R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria 3010, Australia
Brain Res Dev Brain Res 153:243-50. 2004..We conclude that CPI in late gestation affects the expression of BDNF in the fetal hippocampus and cerebellum, but these changes do not have a well-defined relationship to structural outcome...
Effects of exposure to chronic placental insufficiency on the postnatal brain and retina in sheepJhodie R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, Parkville, Victoria, Australia
J Neuropathol Exp Neurol 63:1131-43. 2004..These alterations in the brain can apparently persist from fetal life or become established after birth; some changes that were present in the fetus at term did not persist into postnatal life...
Chronic endotoxin exposure causes brain injury in the ovine fetus in the absence of hypoxemiaJhodie R Duncan
Department of Anatomy and Cell Biology, University of Melbourne, Melbourne, Victoria, Australia
J Soc Gynecol Investig 13:87-96. 2006..CONCLUSIONS: Chronic, systemic exposure of the fetus to LPS resulted in fetal brain damage in the absence of hypoxemia or hypotension, although the resulting injury was less severe than following repeated acute exposure...
