Research Topics
| Denis C BauerSummaryAffiliation: University of Queensland Country: Australia Publications
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Detail Information
Publications
Optimizing static thermodynamic models of transcriptional regulationDenis C Bauer
Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia
Bioinformatics 25:1640-6. 2009..In particular, we see no advantage to using the more sophisticated 'LAM' cooling schedule. Overall, a good approximate solution is achievable in minutes using SA with a simple cooling schedule...
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogasterDenis C Bauer
Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072 Australia
BMC Bioinformatics 11:366. 2010..However, all of the models to date assume a transcription factor (TF) to have either activating or repressing function towards all the genes it is regulating...
STREAM: Static Thermodynamic REgulAtory Model of transcriptionDenis C Bauer
Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia
Bioinformatics 24:2544-5. 2008..AVAILABILITY: The platform independent executable of stream, as well as a tutorial and the full documentation, are available at http://bioinformatics.org.au/stream/. stream requires Java version 5 or higher...
Assigning roles to DNA regulatory motifs using comparative genomicsFabian A Buske
Institute for Molecular Bioscience, The University of Queensland, Brisbane QLD 4072, Australia
Bioinformatics 26:860-6. 2010..Because GOMO uses a threshold-free form of gene set analysis, there are no free parameters to tune. Biologists can investigate the potential roles of DNA regulatory motifs of interest using GOMO via the web (http://meme.nbcr.net)...
Sorting the nuclear proteomeDenis C Bauer
Queensland Brain Institute, School of Chemistry and Molecular Biosciences, Queensland Facility for Advanced Bioinformatics, The University of Queensland, St Lucia, Australia
Bioinformatics 27:i7-14. 2011..We create diagrams illustrating the outcomes of a Gene Ontology enrichment analysis. Associated with an extensive range of transcription factors, the analysis suggests that PML bodies coordinate regulatory immune responses...
STAR: predicting recombination sites from amino acid sequenceDenis C Bauer
Institute for Molecular Bioscience, The University of Queensland, QLD 4072, Australia
BMC Bioinformatics 7:437. 2006..The prohibitive requirements for applying current tools led us to investigate machine learning to assist in finding useful recombination sites from amino acid sequence alone...
Studying the functional conservation of cis-regulatory modules and their transcriptional outputDenis C Bauer
Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072 Australia
BMC Bioinformatics 9:220. 2008....
