Research Topics
| Rachel HuxleySummaryAffiliation: The George Institute for International Health Country: Australia Publications
| Collaborators
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Detail Information
Publications
Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertensionR Huxley
The George Institute for International Health, Sydney, NSW, Australia
Obes Rev 9:53-61. 2008....- Body mass index, waist circumference and waist:hip ratio as predictors of cardiovascular risk--a review of the literatureR Huxley
Renal and Metabolic Division, The George Institute for International Health, The University of Sydney, Sydney, Australia
Eur J Clin Nutr 64:16-22. 2010..associated with cardiovascular risk? (2) Which of the anthropometric measures is a better discriminator of risk? and (3) Are there any notable differences in the strength and nature of these associations across diverse ethnic groups?.. - Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysisRachel Huxley
The George Institute for International Health, The University of Sydney, Australia
Arch Intern Med 169:2053-63. 2009..Similar associations have also been reported for decaffeinated coffee and tea. We report herein the findings of meta-analyses for the association between coffee, decaffeinated coffee, and tea consumption with risk of diabetes... - The impact of modifiable risk factors on mortality from prostate cancer in populations of the Asia-Pacific regionRachel Huxley
Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
Asian Pac J Cancer Prev 8:199-205. 2007..77 (0.56 - 1.05). Body size is an apparently important determinant of prostate cancer in the Asia-Pacific. Evidence of an adverse effect of smoking is conclusive only in the predominantly Caucasian parts of the region... - The role of lifestyle risk factors on mortality from colorectal cancer in populations of the Asia-Pacific regionRachel Huxley
Asia Pacific Cohort Studies Collaboration Secretariat, The George Institute for International Health, Sydney, NSW, Australia
Asian Pac J Cancer Prev 8:191-8. 2007..Understanding such mechanisms could provide opportunities for novel preventive and therapeutic intervention... - Impact of smoking and smoking cessation on lung cancer mortality in the Asia-Pacific regionR Huxley
Nutrition and Lifestyle Division, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Am J Epidemiol 165:1280-6. 2007..These results suggest that tobacco control policies in Asia should not solely concentrate on preventing the uptake of smoking but also attend to cessation... - Smoking, diabetes and cardiovascular diseases in men in the Asia Pacific regionAndre Pascal Kengne
The George Institute for International Health, The University of Sydney, NSW, Australia
J Diabetes 1:173-81. 2009..To assess whether there is a statistical interaction between smoking and diabetes that is related to the risk of cardiovascular disease (CVD) in men in the Asia Pacific region... - Ethnic comparisons of obesity in the Asia-Pacific region: protocol for a collaborative overview of cross-sectional studiesRachel Huxley
The George Institute for International Health, University of Sydney, Sydney, NSW 2050, Australia
Obes Rev 6:193-8. 2005..It will also provide a strong evidence base upon which to define ethnic-specific cut-points for overweight and obesity... - Blood pressure is a major risk factor for renal death: an analysis of 560 352 participants from the Asia-Pacific regionConall M O'Seaghdha
George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia
Hypertension 54:509-15. 2009..10). The results were similar for cohorts in Asia and Australia. These results suggest that primary prevention strategies for renal disease should focus on individuals with elevated blood pressure, diabetes mellitus, and dyslipidemia... - Impact of blood pressure lowering on cardiovascular outcomes in normal weight, overweight, and obese individuals: the Perindopril Protection Against Recurrent Stroke Study trialSebastien Czernichow
George Institute for International Health, University of Sydney, Sydney, Australia
Hypertension 55:1193-8. 2010..However, the greater baseline level of cardiovascular risk in those with higher body mass index meant that these patients obtained the greatest benefit... - Does sex matter in the associations between classic risk factors and fatal coronary heart disease in populations from the Asia-Pacific region?Rachel Huxley
The George Institute for International Health, University of Sydney, NSW, Australia
J Womens Health (Larchmt) 14:820-8. 2005..Previous comparative studies have generally had insufficient numbers of women to quantify such differences reliably... - The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trialsSebastien Czernichow
The George Institute, Sydney, Australia
J Hypertens 29:4-16. 2011..The objective was to compare the risk reductions achieved by different blood pressure-lowering regimens among individuals with different baseline blood pressures... - Blood pressure variables and cardiovascular risk: new findings from ADVANCEAndre Pascal Kengne
ADVANCE Collaborative Group, The George Institute for International Health, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
Hypertension 54:399-404. 2009..However, SBP may be the simplest and most useful predictor across a wider range of age groups and populations... - Cigarette smoking, systolic blood pressure, and cardiovascular diseases in the Asia-Pacific regionKoshi Nakamura
Nutrition and Lifestyle Division, The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW 2050, Australia
Stroke 39:1694-702. 2008..If these 2 risk factors have a synergistic impact on cardiovascular events, lowering BP and quitting smoking will contribute more to reducing CVD than would be expected from ignoring their interaction... - The relationship between proteinuria and coronary risk: a systematic review and meta-analysisVlado Perkovic
The George Institute for International Health, Sydney, New South Wales, Australia
PLoS Med 5:e207. 2008..We therefore undertook a systematic review of published cohort studies aiming to provide a reliable estimate of the strength of association between proteinuria and coronary heart disease... - The effect of modifiable risk factors on pancreatic cancer mortality in populations of the Asia-Pacific regionAlireza Ansary-Moghaddam
The George Institute, University of Sydney, Australia
Cancer Epidemiol Biomarkers Prev 15:2435-40. 2006..Activities to prevent them can be expected to lead to a major reduction in the number of deaths from this cancer, particularly in Asia with its enormous population... - Elevated total cholesterol: its prevalence and population attributable fraction for mortality from coronary heart disease and ischaemic stroke in the Asia-Pacific regionMark Woodward
The George Institute for International Health, University of Sydney, Australia
Eur J Cardiovasc Prev Rehabil 15:397-401. 2008..About half of the world's cases of cardiovascular disease occur in the Asia-Pacific region. The contribution of serum total cholesterol (TC) to this burden is poorly quantified... - Temporal trends in overweight and obesity of children and adolescents from nine Provinces in China from 1991-2006Zhaohui Cui
The George Institute for International Health, University of Sydney, NSW, Australia
Int J Pediatr Obes 5:365-74. 2010..To assess temporal changes in mean body mass index (BMI) and the impact of socio-economic status on the prevalence of overweight and obesity among Chinese children and adolescents in nine provinces between 1991 and 2006... - Is birth weight a risk factor for ischemic heart disease in later life?Rachel Huxley
George Institute, University of Sydney, Sydney, Australia
Am J Clin Nutr 85:1244-50. 2007..An inverse association between birth weight and ischemic heart disease (IHD) has been seen in observational studies... - Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 eventsAlireza Ansary Moghaddam
The George Institute for International Health, Sydney, Australia
Cancer Epidemiol Biomarkers Prev 16:2533-47. 2007..Previous reviews have suggested that obesity may be associated with 30% to 60% greater risk of colorectal cancer, but little consideration was given to the possible effect of publication bias on the reported association... - Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathySophia Zoungas
University of Sydney, Sydney, Australia
Ann Intern Med 151:631-8. 2009..Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN)... - Burden of lung cancer deaths due to smoking for men and women in the WHO Western Pacific and South East Asian regionsAlexandra Martiniuk
The George Institute for International Health, Sydney, Australia
Asian Pac J Cancer Prev 11:67-72. 2010..Eighty percent of all smokers live in low and middle-income countries of the Asia Pacific region but actual estimates of the burden of disease due to smoking in the region have yet to be quantified... - The development of a national salt reduction strategy for AustraliaJacqui Webster
George Institute for International Health, Missenden Road, Sydney, NSW 2050, Australia
Asia Pac J Clin Nutr 18:303-9. 2009..With industry and government engagement, this promises to be a highly effective, low cost option for preventing chronic disease... - The burden of blood pressure-related disease: a neglected priority for global healthVlado Perkovic
George Institute for International Health, University of Sydney, Royal Prince Alfred Hospital, NSW, Australia
Hypertension 50:991-7. 2007 - Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studiesRachel Huxley
George Institute for International Health, University of Sydney, PO Box M201, Sydney, NSW 2050, Australia
BMJ 332:73-8. 2006..To estimate the relative risk for fatal coronary heart disease associated with diabetes in men and women... - Fatal flaw in the fetal argumentRachel Huxley
The George Institute University of Sydney, NSW, Australia
Br J Nutr 95:441-2. 2006 - Associations between high-density lipoprotein cholesterol and both stroke and coronary heart disease in the Asia Pacific regionMark Woodward
Eur Heart J 28:2653-60. 2007..The inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD) is well established. Questions remain about the association between HDL cholesterol and stroke, particularly for stroke subtypes... - Adult height and the risks of cardiovascular disease and major causes of death in the Asia-Pacific region: 21,000 deaths in 510,000 men and womenCrystal Man Ying Lee
The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
Int J Epidemiol 38:1060-71. 2009..We sought to determine the sex- and region-specific associations between height and cardiovascular outcomes, and deaths due to cancer, respiratory and injury in populations from the Asia-Pacific region... - Association of smoking and smoking cessation with major causes of mortality in the Asia Pacific Region: the Asia Pacific Cohort Studies CollaborationF Barzi
The George Institute for International Health, PO Box M201, Missenden Road, Sydney, NSW 2050, Australia
Tob Control 17:166-72. 2008..We investigated the associations between smoking (including ex-smoking) and major causes of mortality in Asian men and women, and compared with Australians and New Zealanders (ANZ)... - Cohort profile: the Asia Pacific Cohort Studies CollaborationM Woodward
The George Institute, University of Sydney, Australia
Int J Epidemiol 35:1412-6. 2006 - The effects of a reduced-sodium, high-potassium salt substitute on food taste and acceptability in rural northern ChinaNicole Li
The George Institute for International Health, University of Sydney, PO Box M201, Camperdown, Sydney, NSW 2050, Australia
Br J Nutr 101:1088-93. 2009..Possible small differences in flavour did not importantly deter the use of the salt substitute in this study group, although the acceptability of the salt substitute by a more general population group would need to be confirmed... - The fraction of ischaemic heart disease and stroke attributable to smoking in the WHO Western Pacific and South-East Asian regionsA L C Martiniuk
The George Institute for International Health, PO Box M201, Missenden Road, Camperdown, NSW, 2050, Australia
Tob Control 15:181-8. 2006..Tobacco will soon be the biggest cause of death worldwide, with the greatest burden being borne by low and middle-income countries where 8/10 smokers now live... - Proteinuria and stroke: a meta-analysis of cohort studiesToshiharu Ninomiya
The George Institute for International Health, The University of Sydney, Sydney, Australia
Am J Kidney Dis 53:417-25. 2009..We undertook a meta-analysis of published cohort studies to provide a reliable estimate of the strength of association between proteinuria and risk of stroke... - Commentary: Modifying body weight not birthweight is the key to lowering blood pressureRachel Huxley
Institute for International Health, 144 Burren Street, Newtown, Sydney, NSW 2042, Australia
Int J Epidemiol 31:1051-3. 2002 - Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studiesR Huxley
The George Institute for International Health, The University of Sydney, PO Box M201, Missenden Road, Sydney NSW 2050, Australia
Br J Cancer 92:2076-83. 2005..1 vs 1.5; P=0.005). These results support a modest causal association between type-II diabetes and pancreatic cancer... - The discrimination of dyslipidaemia using anthropometric measures in ethnically diverse populations of the Asia-Pacific Region: the Obesity in Asia CollaborationF Barzi
The George Institute for International Health, University of Sydney, Sydney, Australia
Obes Rev 11:127-36. 2010..WHR cut-points of 0.8 for women and 0.9 for men are optimal for discriminating those individuals likely to have adverse lipid profiles and in need of further clinical assessment... - Birth weight and subsequent cholesterol levels: exploration of the "fetal origins" hypothesisRachel Huxley
The George Institute, University of Sydney, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW, Australia
JAMA 292:2755-64. 2004..Inverse associations between birth weight and subsequent blood cholesterol levels have been used to support the "fetal origins" hypothesis of the relevance of fetal nutrition to adult disease... - Leisure-time physical activity alone may not be a sufficient public health approach to prevent obesity--a focus on ChinaA Bauman
Institute for Obesity, Nutrition and Exercise, and School of Public Health, University of Sydney, Sydney, New South Wales, Australia
Obes Rev 9:119-26. 2008..These will pose policy challenges in the developing world, if they are to be taken seriously as obesity prevention strategies... - Waist circumference thresholds provide an accurate and widely applicable method for the discrimination of diabetesRachel Huxley
Diabetes Care 30:3116-8. 2007 - International Society of Hypertension (ISH): statement on blood pressure lowering and stroke preventionJohn Chalmers
J Hypertens 21:651-63. 2003..The meeting was conducted under the auspice of the Austin Hospital Medical Research Foundation, Melbourne... - Cholesterol, coronary heart disease and stroke: a review of published evidence from observational studies and randomized controlled trialsRachel Huxley
Department of Public Health Sciences, University of Oxford, Oxford, England
Semin Vasc Med 2:315-23. 2002..8 mmol/l (that is by 10 to 15%), with four fifths of this reduction being in LDL cholesterol... - Unravelling the fetal origins hypothesis: is there really an inverse association between birthweight and subsequent blood pressure?Rachel Huxley
Institute of Health Sciences, University of Oxford, Oxford, UK
Lancet 360:659-65. 2002..It had been estimated that a 1 kg higher birthweight is typically associated with a 2-4 mm Hg lower systolic blood pressure...