David E Gyorki

Summary

Affiliation: The Walter and Eliza Hall Institute of Medical Research
Country: Australia

Publications

  1. ncbi Resident macrophages influence stem cell activity in the mammary gland
    David E Gyorki
    VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia
    Breast Cancer Res 11:R62. 2009
  2. ncbi Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14
    Marie Liesse Asselin-Labat
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Mol Cell Biol 31:4609-22. 2011
  3. ncbi Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Nat Med 15:907-13. 2009
  4. ncbi Macrophages, more than just scavengers: their role in breast development and cancer
    David E Gyorki
    VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Melbourne, Victoria, Australia
    ANZ J Surg 78:432-6. 2008

Collaborators

Detail Information

Publications4

  1. ncbi Resident macrophages influence stem cell activity in the mammary gland
    David E Gyorki
    VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia
    Breast Cancer Res 11:R62. 2009
    ..Here we have explored a role for macrophages in regulating mammary stem cell (MaSC) activity, by assessing the ability of MaSCs to reconstitute a mammary gland in a macrophage-depleted fat pad...
  2. ncbi Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14
    Marie Liesse Asselin-Labat
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Mol Cell Biol 31:4609-22. 2011
    ..Overall, these studies identify GATA-3 as an important regulator of tumor initiation through its ability to promote the differentiation of committed luminal progenitor cells...
  3. ncbi Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    Elgene Lim
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    Nat Med 15:907-13. 2009
    ..Our findings suggest that an aberrant luminal progenitor population is a target for transformation in BRCA1-associated basal tumors ...
  4. ncbi Macrophages, more than just scavengers: their role in breast development and cancer
    David E Gyorki
    VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Melbourne, Victoria, Australia
    ANZ J Surg 78:432-6. 2008
    ..Intriguingly, macrophages are often found in the stroma of breast tumours, where they may promote tumour growth and metastasis. In this review we discuss this emerging area of developmental and tumour biology...