Research Topics
| J TurnidgeSummaryAffiliation: South Australia Country: Australia Publications
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Detail Information
Publications
Statistical characterisation of bacterial wild-type MIC value distributions and the determination of epidemiological cut-off valuesJ Turnidge
Division of Laboratory Medicine, Women s and Children s Hospital, North Adelaide, South Australia 5006, Australia
Clin Microbiol Infect 12:418-25. 2006..5% of MIC values fall within the cut-off value range. Non-linear regression fitting to a cumulative log-normal distribution is a novel and effective method for modelling MIC distributions and quantifying wild-type MIC ranges...- Antibiotic use in animals--prejudices, perceptions and realitiesJohn Turnidge
Division of Laboratory Medicine, Women s and Children s Hospital, North Adelaide, South Australia
J Antimicrob Chemother 53:26-7. 2004..The article by Phillips et al. in this issue puts one view, this article aims to consider the merits of the arguments put forward by both sides and looks to a way forward... - Low levels of fluoroquinolone resistance in Escherichia coli. A five-year trend in Australia measured through the use of TSN Database AustraliaJohn Turnidge
Women s and Children s Hospital, Microbiology Department, North Adelaide, South Australia
Commun Dis Intell 27:S89-91. 2003..Norfloxacin results are likely to be a better guide to fluoroquinolone resistance in this species using this method of surveillance... - TSN Database Australia, a new tool to monitor antimicrobial resistance in AustraliaJohn Turnidge
Women s and Children s Hospital, Microbiology Department, North Adelaide, South Australia
Commun Dis Intell 27:S67-9. 2003..This article will describe TSN in greater detail, describe the query tool and some of the analyses that are possible... - Pharmacodynamics and dosing of aminoglycosidesJohn Turnidge
Division of Laboratory Medicine, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA, 5062, Australia
Infect Dis Clin North Am 17:503-28, v. 2003..Dosages for different clinical settings have been studied and methods are available to monitor once-daily dosing... - Antibiotic use and resistance--proving the obviousJohn Turnidge
Women's and Children's Hospital, North Adelaide, South Australia 5062, Australia
Lancet 365:548-9. 2005 - Responsible prescribing for upper respiratory tract infectionsJ Turnidge
Department of Microbiology and Infectious Diseases, Women s and Children s Hospital, North Adelaide, South Australia, Australia
Drugs 61:2065-77. 2001..Detailed strategies for acute sinusitis have not been worked out but restricting antibacterial prescribing to certain clinical complexes is currently recommended by several authorities because of the high natural resolution rate... - Methicillin-resistant Staphylococcal aureus evolution in Australia over 35 yearsJ D Turnidge
Department of Microbiology and Infectious Diseases, Women s and Children s Hospital, North Adelaide, South Australia, Australia
Microb Drug Resist 6:223-9. 2000..It has a similar antibiogram to the western strains, but an entirely different epidemiology, resembling that currently being experienced in parts of New Zealand, and associated with patients of south Pacific island origin... - Pharmacokinetics and pharmacodynamics of fluoroquinolonesJ Turnidge
Women s and Children s Hospital, North Adelaide, South Australia, Australia
Drugs 58:29-36. 1999..These values can be used to predict the efficacy of different agents against different pathogens, and to define pharmacodynamic 'breakpoints'... - Resistance to fusidic acidJ Turnidge
Department of Microbiology and Infectious Diseases, Women s and Children s Hospital, North Adelaide, SA, Australia
Int J Antimicrob Agents 12:S35-44. 1999..However, evidence suggests that it does not occur at high frequency in clinical practice. Nevertheless, accumulated experience is that fusidic acid in combination with other agents results in less resistance emergence... - Fusidic acid pharmacology, pharmacokinetics and pharmacodynamicsJ Turnidge
Department of Microbiology and Infectious Diseases, Women s and Children s Hospital, North Adelaide SA, Australia
Int J Antimicrob Agents 12:S23-34. 1999..Little is known about the pharmacodynamics of fusidic acid, apart from the fact that it is slowly bactericidal against Staphylococcus aureus, and produces moderate post-antibiotic effects in vitro... - Rapidly emerging antimicrobial resistances in Streptococcus pneumoniae in Australia. Pneumococcal Study GroupJ D Turnidge
Women s and Children s Hospital, Adelaide, SA
Med J Aust 170:152-5. 1999..To examine the prevalence of resistance in Streptococcus pneumoniae to key antimicrobials in Australia during 1997... - Impact of antibiotic resistance on the treatment of sepsisJohn Turnidge
Women s and Children s Hospital, North Adelaide, South Australia, Australia
Scand J Infect Dis 35:677-82. 2003..There is now convincing evidence that broad-spectrum initial therapy to cover the likely pathogens and their resistances pending culture results is mandatory in sepsis to minimize adverse outcomes... - Emergence of vancomycin-resistant enterococci in Australia: phenotypic and genotypic characteristics of isolatesJ M Bell
National Antimicrobial Resistance Surveillance Program, Women s and Children s Hospital, North Adelaide, Australia
J Clin Microbiol 36:2187-90. 1998..Rapid and accurate methods are essential, because laboratory-based surveillance is critical in programs for the detection, control, and prevention of the transmission of glycopeptide-resistant enterococci... - Staphylococcus aureus bacteraemia: a major cause of mortality in Australia and New ZealandJohn D Turnidge
Women s and Children s Hospital, Adelaide, SA, Australia
Med J Aust 191:368-73. 2009..To document the types of, and mortality from, Staphylococcus aureus bacteraemia in Australia and New Zealand, and determine factors associated with mortality... - Selection of SHV extended-spectrum-beta-lactamase-dependent cefotaxime and ceftazidime resistance in Klebsiella pneumoniae requires a plasmid-borne blaSHV geneDavid S Hammond
Institute of Health and Biomedical Innovation, Queensland University of Technology, Cnr Blamey St and Musk Ave, Kelvin Grove, Queensland 4059, Australia
Antimicrob Agents Chemother 52:441-5. 2008..It was concluded that plasmid-borne bla(SHV) greatly facilitates the selection of ESBL expression, even when the same gene is on the chromosome, and that gene dosage effects are likely to contribute to this phenomenon... - Setting and revising antibacterial susceptibility breakpointsJohn Turnidge
Division of Laboratory Medicine, Women s and Children s Hospital, 72 King William Rd, North Adelaide, South Australia, Australia
Clin Microbiol Rev 20:391-408, table of contents. 2007..Breakpoint-setting organizations may also play a role in developing phenotypic tests for detection of resistance mechanisms, as this information may complement use of the breakpoint in some circumstances... - Prevalence of antimicrobial resistances in common pathogenic Enterobacteriaceae in Australia, 2004: report from the Australian Group on Antimicrobial ResistanceJulie Pearson
Department of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, Royal Perth Hospital, Western Australia
Commun Dis Intell 31:106-12. 2007..Both of these types of resistance represent a significant threat to major last-line antibiotics... - Statistical methods for establishing quality control ranges for antibacterial agents in Clinical and Laboratory Standards Institute susceptibility testingJohn Turnidge
Division of Laboratory Medicine, Women s and Children s Hospital, 72 King William Rd, North Adelaide, South Australia 5006, Australia
Antimicrob Agents Chemother 51:2483-8. 2007..Application of statistical techniques to the analysis of QC tier 2 data and the setting of QC ranges is relatively simple to perform on spreadsheets, and the output enhances the current CLSI methods for setting of QC ranges... - Therapeutic drug monitoring of once daily tobramycin in cystic fibrosis--caution with trough concentrationsKingsley P Coulthard
Adelaide Women s and Children s Hospital, Pharmacy Department, Australia
J Cyst Fibros 6:125-30. 2007..This study aimed to compare the exposures to ODD of tobramycin in adults and children with cystic fibrosis using the AUC and trough TDM approaches... - Time for a change? Yes, but not to ciprofloxacinJohn Turnidge
J Paediatr Child Health 42:221; author reply 222-3. 2006 - Laboratory surveillance of invasive pneumococcal disease in Australia, 2003 predicting the future impact of the universal childhood conjugate vaccine programMichael Watson
The NSW Pneumococcal Reference Laboratory, Department of Microbiology, The Children s Hospital at Westmead, Westmead, New South Wales
Commun Dis Intell 28:455-64. 2004.... - A risk analysis framework for the long-term management of antibiotic resistance in food-producing animalsJanet G Salisbury
Biotext, 113 Hopetoun Circuit, Yarralumla, ACT 2600, Australia
Int J Antimicrob Agents 20:153-64. 2002..Risk minimisation may then include control of antibiotic use and/or the reduction of the spread of bacterial infection and/or prevention of transfer of resistance determinants between bacterial populations... - Laboratory surveillance of invasive pneumococcal disease in Australia in 2001 to 2002--implications for vaccine serotype coverageMichael Watson
New South Wales Pneumococcal Reference Laboratory, Department of Microbiology, Children s Hospital at Westmead, New South Wales
Commun Dis Intell 27:478-87. 2003.... - Have South Australian isolates of Neisseria meningitidis become less susceptible to penicillin, rifampicin and other drugs? A study of strains isolated over three decades, 1971-1999David Hansman
Microbiology and Infectious Diseases Department, Women's and Children's Hospital, North Adelaide, SA Australia
Pathology 36:160-5. 2004..Relative insusceptibility to rifampicin was more common but did not increase during the 29-year period. For all drugs tested, except rifampicin, there was good agreement between agar dilution and E test results... - SENTRY Antimicrobial Surveillance Program Asia-Pacific region and South AfricaJan Bell
Microbiology and Infectious Diseases, Women s and Children s Hospital, Adelaide, South Australia
Commun Dis Intell 27:S61-6. 2003..The data generated from SENTRY allows Australia to compare our antimicrobial resistance patterns and trends with our regional neighbours... - Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosisJian Li
Centre for Pharmaceutical Research, School of Pharmaceutical, Molecular and Biomedical Sciences, University of South Australia, Adelaide, Australia
J Antimicrob Chemother 52:987-92. 2003..CONCLUSIONS: Based on the in vitro pharmacodynamics against Pseudomonas aeruginosa previously published by our group and these pharmacokinetic findings, dose escalating trials may be warranted to maximize efficacy... - Pathogen occurrence and antimicrobial resistance trends among urinary tract infection isolates in the Asia-Western Pacific Region: report from the SENTRY Antimicrobial Surveillance Program, 1998-1999John Turnidge
The Women's and Children's Hospital, Adelaide, Australia
Int J Antimicrob Agents 20:10-7. 2002..7%). The data presented are compared to studies of similar design from other areas which are part of the SENTRY surveillance network... - Lower respiratory tract infections and community acquired pneumonia in adultsNigel Stocks
Department of General Practice, University of Adelaide, South Australia
Aust Fam Physician 33:297-301. 2004..Acute bronchitis is often treated with antibiotics, although the cause is usually viral. Community acquired pneumonia may be fatal, particularly in the elderly, therefore appropriate assessment and management is essential...