Research Topics
| F NewallSummaryAffiliation: Royal Children's Hospital Country: Australia Publications
| Collaborators
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Detail Information
Publications
Assessing the outcome of systemic tissue plasminogen activator for the management of venous and arterial thrombosis in pediatricsFiona Newall
Clinical Haematology Department, Royal Children s Hospital, Parkville, Vic, Australia
J Pediatr Hematol Oncol 29:269-73. 2007..More cohort studies reporting the outcome of uniform protocols of thrombolytic therapy in children are required...- Clinical use of unfractionated heparin therapy in children: time for change?Fiona Newall
Department of Paediatrics, The University of Melbourne, Parkville, Vic, Australia
Br J Haematol 150:674-8. 2010..There is an urgent need for change in our approach to the use of UFH in children... - Refinement and feasibility testing of a manual micro-method for protamine titrationF Newall
Department of Pathology, The University of Melbourne, Melbourne, Australia
Int J Lab Hematol 31:457-61. 2009..This protamine titration method may offer an alternative to anti-Xa assays for clinical monitoring of children on heparin therapy, and will enhance clinical studies investigating paediatric-specific management of UFH therapy... - Optimising anticoagulant education in the paediatric setting using a validated model of educationFiona Newall
Clinical Haematology Department, Royal Children s Hospital, Melbourne, Australia
Patient Educ Couns 73:384-8. 2008..Providing education to patients requiring anticoagulant therapy may be associated with improved outcomes. This study investigated the knowledge outcomes of a validated educational intervention... - A survey of pediatric cardiology nurses' understanding of warfarin therapyF Newall
Department of Haematology, Royal Children s Hospital, Melbourne, Australia
Pediatr Cardiol 27:204-8. 2006..The impact of this lack of knowledge on the effectiveness of patient education has not been evaluated, but it is unlikely to be helpful... - Home INR monitoring of oral anticoagulant therapy in children using the CoaguChek S point-of-care monitor and a robust education programFiona Newall
Department of Clinical Haematology, Royal Children s Hospital, Melbourne, Australia
Thromb Res 118:587-93. 2006..This study aimed to improve the outcomes of home monitoring of warfarin therapy in children through the development and implementation of a robust intervention, based upon the PRECEDE model of education... - In vivo age dependency of unfractionated heparin in infants and childrenFiona Newall
Department of Pathology, The University of Melbourne, Parkville, VIC 3010
Thromb Res 123:710-4. 2009..In vitro studies have shown that this practice may be suboptimal. This study aimed to improve the understanding of the impact of age upon UFH response in vivo... - Unfractionated heparin therapy in infants and childrenFiona Newall
MN, BSci, Royal Children s Hospital, Clinical Haematology Department, 9th Floor, Main Building, Flemington Road, Parkville, Victoria 3052, Australia
Pediatrics 123:e510-8. 2009.... - Age-related plasma reference ranges for two heparin-binding proteins--vitronectin and platelet factor 4F Newall
Department of Pathology, The University of Melbourne, Parkville, Melbourne, Vic, Australia
Int J Lab Hematol 31:683-7. 2009..Future studies are required to evaluate the possible impact of age-dependent differences in binding between heparin-binding proteins and UFH... - Age is a determinant factor for measures of concentration and effect in children requiring unfractionated heparinFiona Newall
Department of Paediatrics, The University of Melbourne, Melbourne, Australia
Thromb Haemost 103:1085-90. 2010..The trend toward increased UFH serum concentration and anticoagulant activity with age may be related to short-term differences in UFH binding to coagulant and competitive plasma proteins in vivo... - Novel interactions between UFH and TFPI in childrenFiona Newall
Department of Paediatrics, The University of Melbourne, Royal Children s Hospital, Parkville, Victoria, Australia
Br J Haematol 151:376-80. 2010.... - Arterial ischaemic stroke in childrenC Barnes
Department of Haematology, Royal Children's Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 40:384-7. 2004.... - Heparin-induced thrombocytopenia in childrenF Newall
Department of Haematology, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia
J Paediatr Child Health 39:289-92. 2003..Improved laboratory techniques could facilitate improved screening and diagnosis of this serious adverse drug reaction... - Point-of-care monitoring of oral anticoagulation therapy in children. Comparison of the CoaguChek XS system with venous INR and venous INR using an International Reference Thromboplastin preparation (rTF/95)Anthea Greenway
Department of Haematologg, The Royal Children s Hospital, Parkville, Australia
Thromb Haemost 102:159-65. 2009..This resulted in infrequent changes to clinical decision making regarding anticoagulation... - Age-related differences in heparin responseVera Ignjatovic
Department of Haematology, Royal Children s Hospital, Flemington Road, Parkville 3052, Victoria, Australia
Thromb Res 118:741-5. 2006..This study aimed to determine whether heparin therapeutic range determination is affected by the age of plasma donors and whether age-specific therapeutic ranges for heparin therapy may need to be considered in the clinical setting... - Anticoagulation in neonates and children: Pitfalls and dilemmasPaul Monagle
Department of Clinical Haematology, Royal Children s Hospital, Parkville, Victoria 3052, Australia
Blood Rev 24:151-62. 2010..There remains much research to be done in this field, in the meantime clinicians need to carefully consider the evidence available to them and manage each individual patient accordingly... - Developmental haemostasis. Impact for clinical haemostasis laboratoriesPaul Monagle
Department of Haematology, Royal Children s Hospital Melbourne, and University of Melbourne, Grattan Street, Parkville, Victoria 3051, Australia
Thromb Haemost 95:362-72. 2006..Finally we present age related reference ranges for D-dimers, TFPI, and endogenous thrombin potential, previously not described... - Warfarin therapy in children who require long-term total parenteral nutritionFiona Newall
Department of Paediatrics, University of Melbourne, Women's and Children's Health, Parkville, Australia
Pediatrics 112:e386. 2003..Warfarin therapy can be administered safely in children who require long-term TPN. Warfarin prophylaxis seems to prolong CVAD survival... - Point of care monitoring of oral anticoagulant therapy in children: comparison of CoaguChek Plus and Thrombotest methods with venous international normalised ratioVera Ignjatovic
Department of Haematology, Royal Children's Hospital, Melbourne, Victoria, Australia
Thromb Haemost 92:734-7. 2004..5. The CoaguChek method of INR monitoring is a more accurate and reliable method compared to Thrombotest, in the pediatric population tested, and can be safely used to manage oral anticoagulant therapy in children... - Dosing and monitoring of enoxaparin (Low molecular weight heparin) therapy in childrenVera Ignjatovic
Murdoch Children s Research Institute, Melbourne, Vic, Australia
Br J Haematol 149:734-8. 2010..This study demonstrated a 2-3-fold variation in individual dose requirements for LMWH in children <or=5 years of age, and further mandates the need for age-specific dosage requirements in children receiving enoxaparin... - Assessing outcome measures of oral anticoagulation management in childrenSophie Jones
Department of Paediatrics, The University of Melbourne, The Royal Children s Hospital, Flemington Road, Parkville, Victoria, Australia
Thromb Res 127:75-80. 2011.... - Acute idiopathic portal vein thrombosis in a child: a case report and literature reviewChristopher J Fraser
Department of Haematology, Royal Children's Hospital, Melbourne, Australia
Thromb Res 117:279-81. 2006 - Arterial thromboembolic disease: a single-centre case series studyPaul Monagle
Department of Clinical Haematology, Royal Children s Hospital, University of Melbourne, Melbourne, Victoria, Australia
J Paediatr Child Health 44:28-32. 2008..The aim of this study was to determine the prevalence, aetiology, diagnostic criteria, management and outcome of arterial thromboembolism (TE) in a tertiary paediatric centre... - Evaluation of a post-operative thrombin inhibitor replacement protocol to reduce haemorrhagic and thrombotic complications after paediatric liver transplantationWinita Hardikar
Department of Gastroenterology, Royal Children s Hospital, Parkville, Victoria, 3052, Australia
Thromb Res 126:191-4. 2010..This report consists of two complimentary studies examining the frequency of haemostatic complications before and after the introduction of a post-operative thrombin inhibitor replacement therapy protocol at a single institution... - Cerebral sinus venous thrombosis in childrenC Barnes
Department of Haematology, Royal Children's Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 40:53-5. 2004..CONCLUSION: Cerebral SVT in children is associated with significant residual neurological morbidity. Prospective studies to identify predictors of outcome and effective management interventions are required... - Anticoagulation clinics for children achieve improved warfarin managementFiona Newall
Royal Children's Hospital, Melbourne, Australia
Thromb Res 114:5-9. 2004 - Reduced bone density in children on long-term warfarinChris Barnes
Department of Haematology, University of Melbourne, Royal Children's Hospital, Parkville, Australia
Pediatr Res 57:578-81. 2005..The etiology for the reduced bone density is likely to be multifactorial, however, screening of children on long-term warfarin for reduced bone density should be considered... - Post-thrombotic syndromeC Barnes
Royal Children's Hospital, Melbourne, Australia
Arch Dis Child 86:212-4. 2002.... - Comparison of 'time within therapeutic INR range' with 'percentage INR within therapeutic range' for assessing long-term anticoagulation control in children: a rebuttalS Jones
Clinical Haematology Department, The Royal Children s Hospital Departments of Nursing and Paediatrics, The University of Melbourne Department of Paediatrics, The University of Melbourne Haematology Research Group, Murdoch Childrens Research Institute, Parkville, Victoria, Australia
J Thromb Haemost 9:2331-2. 2011..Comparison of time within therapeutic INR range with percentage INR within therapeutic range for assessing long-term anticoagulation control in children: reply to a rebuttal. This issue, pp 2332-3... - Venous thromboembolic disease: a single-centre case series studyFiona Newall
Department of Clinical Haematology, Royal Children's Hospital, Parkville, Victoria, Australia
J Paediatr Child Health 42:803-7. 2006..Optimal diagnostic and treatment interventions for venous thromboembolism have not yet been determined for infants and children, despite the significant incidence of long-term sequelae... - Point-of-care antithrombotic monitoring in childrenFiona Newall
Department of Clinical Haematology, Royal Children s Hospital, Melbourne, Flemington Rd, Parkville 3052, Australia
Thromb Res 118:113-21. 2006..The advent of point-of-care (POC) monitoring of anticoagulant therapy offers a potential solution to this challenge. This paper reviews the published literature relating to POC monitoring of oral anticoagulant therapy in children... - Clinical outcomes of management of CVAD occlusionsCalvin Peng
Department of Paediatrics, The University of Melbourne, Melbourne, Australia
Arch Dis Child 96:885-7. 2011..The authors conclude that tPA is safe and effective in extending the life of occluded CVADs occlusions by months to years but is less effective in implantable ports... - Patient understanding of warfarin therapy: a review of education strategiesFiona Newall
Department of Haematology, Royal Children's Hospital, Parkville, 3053, Australia
Hematology 10:437-42. 2005.... - Temporal aspects of anti-heparin-PF4 antibodies in heparin-induced thrombocytopeniaFiona Newall
Ann Thorac Surg 81:1944; author reply 1944-5. 2006