Research Topics
Species | Finlay MacraeSummaryAffiliation: Royal Melbourne Hospital Country: Australia Publications
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Detail Information
Publications
Familial adenomatous polyposisFinlay Macrae
Department of Colorectal Medicine and Genetics and Familial Cancer Clinic, PO Box 2010, The Royal Melbourne Hospital, Melbourne, Victoria 3050, Australia
Best Pract Res Clin Gastroenterol 23:197-207. 2009..Patients in whom no mutation is identified through this mutation protocol, may be sub-cohorts representing a different FAP pathogenesis including MYH associated polyposis and somatic cell mosaicism for APC gene mutations...
Surveillance of FAP: a prospective blinded comparison of capsule endoscopy and other GI imaging to detect small bowel polypsPaul Tescher
Department of Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Australia
Hered Cancer Clin Pract 8:3. 2010..This study aims to evaluate the effectiveness of CE in the assessment of patients with FAP, compared to other imaging modalities for the detection of small bowel polyps...
A review of juvenile polyposis syndromeElizabeth Chow
Department of Colorectal Medicine and Genetics, Royal Melbourne Hospital, Victoria, Australia
J Gastroenterol Hepatol 20:1634-40. 2005..This article reviews our knowledge to date of the genetics and clinicopathological features of the Juvenile Polyposis Syndrome, and discusses the current expert recommendations for genetic testing, disease screening and management...
Survey of HNPCC Management Analysis of Responses from 18 International Cancer CentresElizabeth Chow
Familial Cancer Clinic, Royal Melbourne Hospital, Victoria, Australia
Hered Cancer Clin Pract 3:137-46. 2005....
Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYHElizabeth Chow
Familial Cancer Clinic, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Gastroenterology 131:30-9. 2006..There is no known germ-line predisposition. We aimed to characterize the clinicopathologic features of 38 patients with HPS and explore the role of germ-line mutations in the base excision repair genes MBD4 and MYH...
A family with juvenile polyposis linked to the BMPR1A locus: cryptic mutation or closely linked gene?Elizabeth Chow
Department of Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Victoria, Australia
J Gastroenterol Hepatol 22:2292-7. 2007..Genetic heterogeneity remains evident, as the balance of cases is not accounted for by mutations in these genes. The aim of this study was to determine the mutation responsible in a family with juvenile polyposis...
Management of cancer risk in Barrett's esophagusAlyisha Tan
School of Medicine, The University of Melbourne, Melbourne, Victoria, Australia
J Gastroenterol Hepatol 26:1485-92. 2011....
Microsatellite instability markers for identifying early-onset colorectal cancers caused by germ-line mutations in DNA mismatch repair genesLeeanne J Mead
Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, Victoria, Australia
Clin Cancer Res 13:2865-9. 2007..We wanted to examine which microsatellite markers currently used to detect MSI best predict early-onset colorectal cancer caused by germ-line mutations in MMR genes...
