Research Topics
| Ralf G HeineSummaryAffiliation: Royal Children's Hospital Country: Australia Publications
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Detail Information
Publications
IgE food sensitization in infants with eczema attending a dermatology departmentDavid J Hill
Murdoch Children s Research Institute, Melbourne, Australia
J Pediatr 151:359-63. 2007....
The diagnosis and management of egg allergyRalf G Heine
Department of Allergy, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
Curr Allergy Asthma Rep 6:145-52. 2006..The treatment of egg allergy consists of dietary elimination, or a maternal elimination diet in breast-fed infants. Approximately two thirds of infants with egg allergy will become tolerant by 7 years of age...
Dietary approaches to the prevention of food allergyRalf G Heine
Department of Allergy and Immunology, Royal Children s Hospital, Department of Paediatrics, University of Melbourne, Parkville, VIC 3052, Australia
Curr Opin Clin Nutr Metab Care 11:320-8. 2008..Although some preventive dietary interventions have entered common practice, the level of evidence underpinning these strategies varies...
Eosinophilic esophagitis: example of an emerging allergic manifestation?Ralf G Heine
Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Melbourne, Victoria, Australia
Nestle Nutr Workshop Ser Pediatr Program 64:105-15; discussion 116-20, 251-7. 2009..These patients may respond to swallowed corticosteroid aerosols or other immune-modulating drugs. Further prospective clinical trials are needed to outline the most effective long-term treatment of EE...
Allergic gastrointestinal motility disorders in infancy and early childhoodRalf G Heine
Department of Gastroenterology and Clinical Nutrition Royal Children s Hospital, University of Melbourne, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia
Pediatr Allergy Immunol 19:383-91. 2008..The following article will present three instructive cases followed by discussion of the clinical presentation, diagnosis, treatment and natural history of food allergic motility disorders in infancy and early childhood...
Pathophysiology, diagnosis and treatment of food protein-induced gastrointestinal diseasesRalf G Heine
Department of Allergy, Royal Children s Hospital, and Department of Paediatrics, University of Melbourne, Victoria, Australia
Curr Opin Allergy Clin Immunol 4:221-9. 2004..Although our general understanding of food hypersensitivity has improved in recent years, gastrointestinal food protein-induced diseases still pose diagnostic and therapeutic dilemmas...
Gastroesophageal reflux disease, colic and constipation in infants with food allergyRalf G Heine
Department of Allergy, Royal Children s Hospital, Parkville, Victoria, Australia
Curr Opin Allergy Clin Immunol 6:220-5. 2006..This review assesses the role of food allergy in the pathophysiology of gastroesophageal reflux disease, colic and constipation in infancy...
Clinical predictors of pathological gastro-oesophageal reflux in infants with persistent distressRalf G Heine
Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Melbourne, Australia
J Paediatr Child Health 42:134-9. 2006..Gastro-oesophageal reflux (GOR) is common in infants with persistent crying. Empirical treatment with antireflux medications is common practice, although on clinical grounds it may be difficult to determine whether GOR is abnormal...
Effect of a low-allergen maternal diet on colic among breastfed infants: a randomized, controlled trialDavid J Hill
Department of Allergy, Royal Children s Hospital, Melbourne, Australia
Pediatrics 116:e709-15. 2005..There is controversy regarding whether hypersensitivity to food proteins contributes to colic among breastfed infants...
Oesophagitis in children: reflux or allergy?Kerryn Ireland-Jenkin
Department of Anatomical Pathology, Royal Children s Hospital, Melbourne, Victoria, Australia
Pathology 40:188-95. 2008..Long-term uncontrolled oesophageal eosinophilic inflammation may lead to progressive subepithelial fibrosis, potentially resulting in strictures or oesophageal narrowing...
Early clinical predictors of remission of peanut allergy in childrenMarco H K Ho
Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Australia
J Allergy Clin Immunol 121:731-6. 2008..Understanding predictors of clinical remission would assist in clinical management of peanut allergy...
Effect of antireflux medication, placebo and infant mental health intervention on persistent crying: a randomized clinical trialBrigid Jordan
Mental Health Service, Royal Children s Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 42:49-58. 2006..To assess the effect of medical antireflux treatment, and of an infant mental health consultation (IMHC), on persistent crying in infants and maternal distress...
4. Food allergy in childhoodKatrina J Allen
Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Victoria, Australia
Med J Aust 185:394-400. 2006..Children often develop tolerance to cows milk, egg, soy and wheat by school age, whereas allergies to nuts and shellfish are more likely to be lifelong...
Egg allergy in childhood: an updateDean Tey
Department of Allergy and Immunology, Royal Children s Hospital, Melbourne, Australia
Curr Opin Allergy Clin Immunol 9:244-50. 2009..In this article, we review the recent literature regarding the immunology, clinical presentation, diagnosis, management and natural history of egg allergy...
Management of cow's milk protein allergy in infants and young children: an expert panel perspectiveKatrina J Allen
Murdoch Childrens Research Institute, Melbourne, Vic, Australia
J Paediatr Child Health 45:481-6. 2009....
The diagnostic value of skin prick testing in children with food allergyDavid J Hill
Department of Allergy, Royal Children s Hospital, Flemington Road, Parkville, Victoria 3052, Australia
Pediatr Allergy Immunol 15:435-41. 2004..0001) and peanut (p < 0.0001). Further studies are required to define age-specific diagnostic IgE antibody and SPT cut-off levels use in infants under 2 yr of age with suspected food allergies...
Factors affecting clinical outcome in gastrostomy-fed children with cystic fibrosisMark R Oliver
Department of Gastroenterology and Nutrition, Royal Children s Hospital, Melbourne, Australia
Pediatr Pulmonol 37:324-9. 2004..32 +/- 0.26 vs. 0.03 +/- 0.39; P = 0.03). In conclusion, the presence of advanced lung disease, GER, and female gender were factors associated with a poor clinical outcome after gastrostomy placement...
Eosinophilic esophagitis: trials and tribulationsKatrina J Allen
Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Melbourne, Australia
J Clin Gastroenterol 45:574-82. 2011..This article aims to discuss the complex issues of the diagnosis and long-term management that confront clinicians who care for children with EE...
Complications associated with endoscopic removal of percutaneous endoscopic gastrostomy (PEG) tubes in childrenGreta M Palmer
Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Australia
J Pediatr Gastroenterol Nutr 42:443-5. 2006
Health and well-being in school-age children following persistent crying in infancyMary Brown
The University of Melbourne, Melbourne, Victoria, Australia
J Paediatr Child Health 45:254-62. 2009..To examine the physical and mental health outcomes at school-age of a cohort of children who participated in a randomised clinical trial of treatments for persistent crying in infancy...
Esophagitis in distressed infants: poor diagnostic agreement between esophageal pH monitoring and histopathologic findingsRalf G Heine
Department of Gastroenterology, Royal Children's Hospital, Melbourne, Australia
J Pediatr 140:14-9. 2002..07). CONCLUSION: Esophagitis occurred in one quarter of infants with persistent distress. Abnormal esophageal pH monitoring did not reliably predict esophagitis, suggesting a nonacid peptic cause in some of these infants...
Cow's milk allergy in infancyRalf G Heine
Department of Allergy, Royal Children s Hospital, Parkville, Victoria, Australia
Curr Opin Allergy Clin Immunol 2:217-25. 2002..The treatment of cow's milk allergy relies on allergen avoidance and hypoallergenic formulae, or maternal elimination diets in breast-fed infants...
Randomized clinical trial of rapid versus 24-hour rehydration for children with acute gastroenteritisColin V E Powell
Departments of aEmergency Medicine, Royal Children s Hospital, Melbourne, Australia
Pediatrics 128:e771-8. 2011..To compare the efficacy of 2 nasogastric rehydration regimens for children with acute viral gastroenteritis...
Body composition of children with chronic and end-stage renal failureAndreas Nydegger
Department of Gastroenterology, Royal Children s Hospital, Parkville, Victoria, Australia
J Paediatr Child Health 43:740-5. 2007..Although the aetiology of malnutrition is multifactorial, descriptive information on body composition may guide nutritional interventions aimed at optimising nutritional status...
Emerging management concepts for eosinophilic esophagitis in childrenRalf G Heine
Department of Gastroenterology and Clinical Nutrition and Royal Children s Hospital, Melbourne, Australia
J Gastroenterol Hepatol 26:1106-13. 2011..This paper aims to discuss the various strategies currently available to clinicians in the management of EoE and highlights gaps in the current evidence base that urgently require further research...
Changing incidence of acute pancreatitis: 10-year experience at the Royal Children's Hospital, MelbourneAndreas Nydegger
Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Melbourne, Victoria, Australia
J Gastroenterol Hepatol 22:1313-6. 2007..The aim of this study was to assess the incidence and etiology of acute pancreatitis at a major pediatric referral center in Australia...
Macrogol 3350 plus electrolytes for chronic constipation in children: a single-centre, open-label studyWinita Hardikar
Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Victoria, Australia
J Paediatr Child Health 43:527-31. 2007..This open-label, non-randomised study aimed to evaluate the safety and efficacy of this preparation in the treatment of chronic constipation in children...
Tolerability and safety of olive oil-based lipid emulsion in critically ill neonates: a blinded randomized trialAnnette N Webb
Department of Gastroenterology and Clinical Nutrition, The Royal Children s Hospital, Melbourne, Victoria, Australia
Nutrition 24:1057-64. 2008..We assessed the safety and tolerability of an olive oil-based lipid emulsion compared with a soybean-based lipid emulsion in critically ill neonates...
Chest physiotherapy in infants with cystic fibrosis: to tip or not? A five-year studyBrenda M Button
Department of Physiotherapy, Royal Children s Hospital, Melbourne, Australia
Pediatr Pulmonol 35:208-13. 2003..03). Forced vital capacity and forced expired volume in 1 sec (FEV(1)) at 5-6 years was lower for SPT than for MPT (P < 0.05). In conclusion, MPT was associated with fewer respiratory complications than SPT in infants with CF...
Eosinophilic oesophagitisAlyson Kakakios
Department of Immunology and Infectious Diseases, The Children's Hospital at Westmead, Sydney, NSW, Australia
Med J Aust 185:401. 2006
Proposal for a standardized interpretation of the atopy patch test in children with atopic dermatitis and suspected food allergyRalf G Heine
Department of Pediatric Pneumology and Immunology, Children's Hospital Charit, Humboldt University, Berlin, Germany
Pediatr Allergy Immunol 17:213-7. 2006..Presence of both induration and of at least seven papules at 72 h were the APT skin signs with the greatest diagnostic accuracy for food allergy in children with AD...
The importance of early complementary feeding in the development of oral tolerance: concerns and controversiesSusan L Prescott
School of Paediatrics and Child Health Research, University of Western Australia, Perth, WA, Australia
Pediatr Allergy Immunol 19:375-80. 2008..It will also examine the growing case for introducing complementary foods from around 4 months of age and maintaining breastfeeding during this early feeding period, for at least 6 months if possible...
Eosinophilic esophagitis in children with celiac disease: new diagnostic and therapeutic dilemmasRalf G Heine
J Gastroenterol Hepatol 23:993-4. 2008
Primary prevention of atopic dermatitis in breast-fed infants: what is the evidence?Ralf G Heine
J Pediatr 144:564-7. 2004
Diagnostic accuracy of skin prick testing in children with tree nut allergyMarco H K Ho
J Allergy Clin Immunol 117:1506-8. 2006
