A Corbould

Summary

Affiliation: Prince Henry's Institute of Medical Research
Country: Australia

Publications

  1. ncbi Insulin resistance in skeletal muscle and adipose tissue in polycystic ovary syndrome: are the molecular mechanisms distinct from type 2 diabetes?
    A Corbould
    Prince Henry s Institute of Medical Research, Australia
    Panminerva Med 50:279-94. 2008
  2. ncbi Effects of androgens on insulin action in women: is androgen excess a component of female metabolic syndrome?
    A Corbould
    Prince Henry s Institute of Medical Research, Clayton, Vic, Australia
    Diabetes Metab Res Rev 24:520-32. 2008
  3. ncbi Effects of spironolactone on glucose transport and interleukin-6 secretion in adipose cells of women
    A Corbould
    Prince Henry s Institute of Medical Research, Clayton, Vic, Australia
    Horm Metab Res 39:915-8. 2007
  4. ncbi The adipose cell lineage is not intrinsically insulin resistant in polycystic ovary syndrome
    Anne Corbould
    Division of Women s Health, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Metabolism 56:716-22. 2007
  5. ncbi Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women
    A Corbould
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Block E, Level 4, Clayton Road, Clayton, Victoria 3168, Australia
    J Endocrinol 192:585-94. 2007
  6. ncbi Insulin resistance in polycystic ovary syndrome: progress and paradoxes
    A M Venkatesan
    The Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
    Recent Prog Horm Res 56:295-308. 2001
  7. ncbi Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways
    L Rui
    Harvard Medical School, Joslin Diabetes Center, 1 Joslin Place, Boston, Massachusetts 02215, USA
    J Clin Invest 107:181-9. 2001
  8. ncbi Regulation of adenosine 5',monophosphate-activated protein kinase and lipogenesis by androgens contributes to visceral obesity in an estrogen-deficient state
    Kerry J McInnes
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, Victoria 3168, Australia
    Endocrinology 147:5907-13. 2006
  9. ncbi Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling
    Anne Corbould
    Division of Women's Health, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Physiol Endocrinol Metab 288:E1047-54. 2005
  10. ncbi Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome
    Anne Corbould
    Division of Endocrinology, Metabolism and Molecular Medicine, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Ave, Chicago, IL 60611, USA
    Diabetes 55:751-9. 2006

Collaborators

Detail Information

Publications10

  1. ncbi Insulin resistance in skeletal muscle and adipose tissue in polycystic ovary syndrome: are the molecular mechanisms distinct from type 2 diabetes?
    A Corbould
    Prince Henry s Institute of Medical Research, Australia
    Panminerva Med 50:279-94. 2008
    ....
  2. ncbi Effects of androgens on insulin action in women: is androgen excess a component of female metabolic syndrome?
    A Corbould
    Prince Henry s Institute of Medical Research, Clayton, Vic, Australia
    Diabetes Metab Res Rev 24:520-32. 2008
    ..Studies of long-term interventions that lower androgen levels or block androgen effects in young women with hyperandrogenism are needed to determine whether these might protect against metabolic syndrome/type 2 diabetes in later life...
  3. ncbi Effects of spironolactone on glucose transport and interleukin-6 secretion in adipose cells of women
    A Corbould
    Prince Henry s Institute of Medical Research, Clayton, Vic, Australia
    Horm Metab Res 39:915-8. 2007
    ..Spironolactone may have a novel role in increasing glucose uptake into adipose cells and attenuating adipose tissue inflammation, with implications for management of metabolic syndrome...
  4. ncbi The adipose cell lineage is not intrinsically insulin resistant in polycystic ovary syndrome
    Anne Corbould
    Division of Women s Health, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Metabolism 56:716-22. 2007
    ....
  5. ncbi Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women
    A Corbould
    Prince Henry s Institute of Medical Research, Monash Medical Centre, Block E, Level 4, Clayton Road, Clayton, Victoria 3168, Australia
    J Endocrinol 192:585-94. 2007
    ..These findings are relevant to understanding the pathogenesis of insulin resistance in hyperandrogenic women...
  6. ncbi Insulin resistance in polycystic ovary syndrome: progress and paradoxes
    A M Venkatesan
    The Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
    Recent Prog Horm Res 56:295-308. 2001
    ..The explanations for tissue-specific and signaling pathway-specific differences in insulin action in PCOS are unknown but may involve differential roles of insulin receptor substrate (IRS)-1 and IRS-2 in insulin signal transduction...
  7. ncbi Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways
    L Rui
    Harvard Medical School, Joslin Diabetes Center, 1 Joslin Place, Boston, Massachusetts 02215, USA
    J Clin Invest 107:181-9. 2001
    ..Thus, distinct kinase pathways might converge at Ser307 to mediate feedback or heterologous inhibition of IRS-1 signaling to counterregulate the insulin response...
  8. ncbi Regulation of adenosine 5',monophosphate-activated protein kinase and lipogenesis by androgens contributes to visceral obesity in an estrogen-deficient state
    Kerry J McInnes
    Prince Henry s Institute of Medical Research, P O Box 5152, Clayton, Victoria 3168, Australia
    Endocrinology 147:5907-13. 2006
    ..These data provide the first in vivo evidence that an increased androgen to estrogen ratio can promote visceral fat accumulation by inhibiting AMPK activation and stimulating lipogenesis...
  9. ncbi Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling
    Anne Corbould
    Division of Women's Health, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Physiol Endocrinol Metab 288:E1047-54. 2005
    ..These abnormalities differ from those reported in other insulin resistant states consistent with the hypothesis that PCOS is a genetically unique disorder conferring an increased risk for type 2 diabetes...
  10. ncbi Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome
    Anne Corbould
    Division of Endocrinology, Metabolism and Molecular Medicine, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Ave, Chicago, IL 60611, USA
    Diabetes 55:751-9. 2006
    ....