Duncan E Crombie

Summary

Affiliation: Monash University

Country: Australia

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro
Duncan E Crombie
Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
Arthritis Res Ther 7:R927-37. 2005
Arthritogenic anti-type II collagen antibodies are pathogenic for cartilage-derived chondrocytes independent of inflammatory cells
S Fatemah Amirahmadi
Monash University, Clayton, Victoria, Australia
Arthritis Rheum 52:1897-906. 2005
An arthritogenic monoclonal antibody to type II collagen, CII-C1, impairs cartilage formation by cultured chondrocytes
S Fatemah Amirahmadi
Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia
Immunol Cell Biol 82:427-34. 2004

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro
Duncan E Crombie
Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
Arthritis Res Ther 7:R927-37. 2005
..We conclude that antibodies to CII can have pathogenic effects that are independent of inflammatory mediators or Fc-binding...
Arthritogenic anti-type II collagen antibodies are pathogenic for cartilage-derived chondrocytes independent of inflammatory cells
S Fatemah Amirahmadi
Monash University, Clayton, Victoria, Australia
Arthritis Rheum 52:1897-906. 2005
..Such effects occur independent of inflammation mediators and are related to the epitope specificity of the mAb. Interference with the structural integrity of CII could precede, and even initiate, the inflammatory expression of disease...
An arthritogenic monoclonal antibody to type II collagen, CII-C1, impairs cartilage formation by cultured chondrocytes
S Fatemah Amirahmadi
Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia
Immunol Cell Biol 82:427-34. 2004
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