Research Topics
| M I McDonaldSummaryAffiliation: Menzies School of Health Research Country: Australia Publications
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Detail Information
Publications
Epidemiology of Streptococcus dysgalactiae subsp. equisimilis in tropical communities, Northern AustraliaMalcolm McDonald
Menzies School of Health Research, Charles Darwin University, Casuarina, Northern Territory, Australia
Emerg Infect Dis 13:1694-700. 2007..These communities already have high levels of streptococcal and poststreptococcal disease. GCS/GGS may increase in importance as it acquires key virulence factors from GAS by lateral gene transfer...
The dynamic nature of group A streptococcal epidemiology in tropical communities with high rates of rheumatic heart diseaseM I McDonald
Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory Australia
Epidemiol Infect 136:529-39. 2008..Throat detection of emmST was brief, usually <2 months. The epidemiology of GAS in these remote Aboriginal communities is a highly dynamic process characterized by emmST diversity and turnover...
Molecular typing of Streptococcus pyogenes from remote Aboriginal communities where rheumatic fever is common and pyoderma is the predominant streptococcal infectionM I McDonald
Menzies School of Health Research, Casuarina, 0811, NT, Australia
Epidemiol Infect 135:1398-405. 2007..2, 95% CI 1.7-3.0). Pattern E favoured the throat (RR 1.4, 95% CI 1.1-1.8). Where environmental factors predispose to skin infection, emm pattern types D and E prevail, whatever the recovery site...
Acute rheumatic fever: a chink in the chain that links the heart to the throat?Malcolm McDonald
Infectious Diseases and International Health Unit, Menzies School of Health Research and Charles Darwin University, Darwin, New Territories, Australia
Lancet Infect Dis 4:240-5. 2004..New understanding of the pathogenesis of ARF would have an immediate effect on primary prevention strategies and vaccine development...
Apparent contrasting rates of pharyngitis and pyoderma in regions where rheumatic heart disease is highly prevalentMalcolm McDonald
Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
Heart Lung Circ 16:254-9. 2007....
Use of a single-nucleotide polymorphism genotyping system to demonstrate the unique epidemiology of methicillin-resistant Staphylococcus aureus in remote aboriginal communitiesMalcolm McDonald
Menzies School of Health Research, P O Box 41096, Casuarina, 0811 Northern Territory, Australia
J Clin Microbiol 44:3720-7. 2006..Monthly tracking of SNP-based cc types showed a highly dynamic process. ST75-MRSA-IV appears to be unique to the region and probably evolved de novo in remote Aboriginal communities...
The challenge of acute rheumatic fever diagnosis in a high-incidence population: a prospective study and proposed guidelines for diagnosis in Australia's Northern TerritoryAnna Ralph
Royal Darwin Hospital, NT, Australia
Heart Lung Circ 15:113-8. 2006....
Recovering streptococci from the throat, a practical alternative to direct plating in remote tropical communitiesMalcolm McDonald
Menzies School of Health Research, P O Box 41096, Casuarina, 0811, NT, Australia
J Clin Microbiol 44:547-52. 2006..In tropical and remote settings, cold-box transport with desiccant and subsequent inoculation of culture plates in the laboratory is a practical alternative to direct plating...
High-resolution melting analysis of the spa locus reveals significant diversity within sequence type 93 methicillin-resistant Staphylococcus aureus from northern AustraliaS Y C Tong
Menzies School of Health Research, Institute of Advanced Studies, Charles Darwin University, Darwin, NT, Australia
Clin Microbiol Infect 15:1126-31. 2009..aureus (MSSA), and the coexistence of MSSA and methicillin-resistant S. aureus versions of the same lineage within northern Australia...
Assessment of a register-based rheumatic heart disease secondary prevention program in an Australian Aboriginal communitySabry Eissa
Royal Free and University College London Medical School, University College London, United Kingdom
Aust N Z J Public Health 29:521-5. 2005..Specific interventions, especially those related to men's health, may be required to correct the problems...
Acute rheumatic feverJonathan R Carapetis
Centre for International Child Health, University of Melbourne Department of Paediatrics and Murdoch Children s Research Institute, Melbourne, Australia
Lancet 366:155-68. 2005..The most effective approach for control of ARF and RHD is secondary prophylaxis, which is best delivered as part of a coordinated control programme...
