Research Topics
Genomes and Genes | Paul S HaberSummaryCountry: Australia Publications
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Publications
Pathogenesis and management of alcoholic hepatitisPaul S Haber
Drug Health Services and AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, and Department of Medicine, University of Sydney, Sydney, Australia
J Gastroenterol Hepatol 18:1332-44. 2003....
Adherence to treatment for recently acquired hepatitis C virus (HCV) infection among injecting drug usersJason Grebely
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
J Hepatol 55:76-85. 2011..We assessed 80/80 adherence (?80% of PEG-IFN doses, ?80% treatment), on-treatment adherence, and treatment completion in a study of treatment of recent HCV infection (ATAHC)...
Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver diseaseDevanshi Seth
Drug Health Services, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia
J Hepatol 48:614-27. 2008..Aim of our study was to study the direct effect of alcohol on fibrinolysis and plasmin activity in hepatic cell lines and in vivo...
Effective treatment of injecting drug users with recently acquired hepatitis C virus infectionGregory J Dore
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
Gastroenterology 138:123-35.e1-2. 2010..We evaluated the efficacy of treatment of recent HCV infection in IDUs with acute and early chronic HCV...
Sample bias from different recruitment strategies in a randomised controlled trial for alcohol dependenceKirsten C Morley
Central Clinical School of Medicine, The University of Sydney, Sydney, Australia
Drug Alcohol Rev 28:222-9. 2009..The current study aims to compare the effects of recruitment method on socio-demographics, baseline illness characteristics, treatment retention and treatment outcome measures...
Establishment of a successful assessment and treatment service for Australian prison inmates with chronic hepatitis CLeng Boonwaat
Blood Borne Viruses and Sexual Assault Services, Population Health, Justice Health, Sydney, NSW, Australia
Med J Aust 192:496-500. 2010..To evaluate the assessment and treatment outcomes of a prison hepatitis service...
Intrahepatic gene expression in human alcoholic hepatitisDevanshi Seth
Drug Health Services, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia
J Hepatol 45:306-20. 2006..Treatment remains unsatisfactory, in part, due to limited understanding of the pathogenesis. The aim of this study is to define the global intrahepatic expression profile of human alcoholic hepatitis...
Alcohol, signaling, and ECM turnoverDevanshi Seth
Drug Health Services and Centenary Institute, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
Alcohol Clin Exp Res 34:4-18. 2010..It highlights the various processes and molecules that are likely involved in inflammation, immune modulation, susceptibility to infection, ECM turnover and fibrogenesis in the liver, pancreas, and lung triggered by alcohol abuse...
Issues with recruitment to randomised controlled trials in the drug and alcohol field: a literature review and Australian case studyClare L Thomson
Drug Health Services, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
Drug Alcohol Rev 27:115-22. 2008..However, subject recruitment is an ongoing challenge for those conducting RCTs and may have a serious impact on the success of the study and the reliability of the outcomes...
Pathogenesis of alcohol-induced liver disease: classical concepts and recent advancesDevanshi Seth
Drug Health Services, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
J Gastroenterol Hepatol 26:1089-105. 2011..There is also a need for adequate animal models to study pathogenic mechanisms at the molecular level and targeted therapy...
Gene expression profiling of alcoholic liver disease in the baboon (Papio hamadryas) and human liverDevanshi Seth
Drug Health Services, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
Am J Pathol 163:2303-17. 2003..The gene expression profile of ALD is dominated by alcohol metabolism and inflammation and differs from other liver diseases. Annexins may play a role in the progression of fibrosis in ALD...
Management of injecting drug users admitted to hospitalPaul S Haber
Drug Health Services, Royal Prince Alfred Hospital, Camperdown, and University of Sydney, Discipline of Addiction Medicine, Sydney, NSW, Australia
Lancet 374:1284-93. 2009..Effective management can reduce the medical and social effect of these conditions and is not difficult...
Unplanned pregnancy and contraceptive use in women attending drug treatment servicesKirsten I Black
Discipline of Obstetrics, Gynaecology and Neonatology, Central Clinical School, Royal Prince Alfred Hospital, University of Sydney, Camperdown
Aust N Z J Obstet Gynaecol 52:146-50. 2012..At an international level, there are calls for a greater focus on women and harm reduction in recognition that female drug users have a unique set of issues that are not routinely assessed in drug treatment programs...
Development of a nurse-led primary healthcare service for injecting drug users in inner-city SydneyCarolyn A Day
Discipline of Addiction Medicine, Central Clinical School C39, Sydney Medical School, University of Sydney, NSW 2006, Australia
Aust J Prim Health 17:10-5. 2011..Targeted primary health care services led by nurses with focussed medical support and co-located with needle and syringe programs can fill an important gap in delivering and facilitating health care to IDUs...
Non-oxidative metabolism of ethanol by rat pancreatic aciniPaul S Haber
Pancreatic Research Group, University of New South Wales, Sydney, Australia
Pancreatology 4:82-9. 2004..Oxidative metabolism of ethanol occurs at a much higher rate and may also play a role in pancreatitis...
Training in addiction medicine in AustraliaPaul S Haber
Drug Health Services, Royal Prince Alfred Hospital and Discipline of Addiction Medicine, University of Sydney, Camperdown, New South Wales, Australia
Subst Abus 32:115-9. 2011..There is no exit examination. The overriding clinical approach rests upon the harm minimization framework consistent with long-established national drug policy in Australia and favors evidence-based treatment...
Risk factors for hepatitis C infection and perception of antibody status among male prison inmates in the Hepatitis C Incidence and Transmission in Prisons Study cohort, AustraliaJennifer A Gates
National Drug and Alcohol Research Centre, UNSW, Sydney, 2052, Australia
J Urban Health 81:448-52. 2004..Prisons are likely to remain an important site for the diagnosis of HCV infection and targeted interventions aimed at risk reduction among inmates with low education levels and a previous imprisonment history...
Naltrexone versus acamprosate in the treatment of alcohol dependence: A multi-centre, randomized, double-blind, placebo-controlled trialKirsten C Morley
Central Clinical School of Medicine, University of Sydney, NSW, Australia
Addiction 101:1451-62. 2006..No effect of acamprosate was found in our sample...
Hazardous alcohol consumption and other barriers to antiviral treatment among hepatitis C positive people receiving opioid maintenance treatmentBianca Watson
Royal Prince Alfred Hospital, Sydney, Australia
Drug Alcohol Rev 26:231-9. 2007..Brief intervention for alcohol use problems was acceptable to OMT patients, and warrants further study...
The outcome of a rapid hepatitis B vaccination programme in a methadone treatment clinicParameswaran Ramasamy
Drug Health Service, Sydney South West Area Health Service, Sydney, Australia
Addiction 105:329-34. 2010..This study examines the completion rates of a HBV vaccination schedule and seroconversion in a group of patients in methadone maintenance treatment...
Transmission of hepatitis C virus by needle-stick injury in community settingsPaul S Haber
Royal Prince Alfred Hospital and Discipline of Medicine, University of Sydney, Sydney, New South Wales, Australia
J Gastroenterol Hepatol 22:1882-5. 2007..Hepatitis C virus (HCV) is predominantly transmitted by blood-to-blood contact, typically by sharing of needles by injecting drug users. Discarded needles could act as a vector for transmission of this infection...
SMART amplification maintains representation of relative gene expression: quantitative validation by real time PCR and application to studies of alcoholic liver disease in primatesDevanshi Seth
Drug Health Services and A.W. Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital and Centenary Institute of Cancer Medicine and Cell Biology, Camperdown, NSW 2050, Australia
J Biochem Biophys Methods 55:53-66. 2003....
