Christine A Wells

Summary

Affiliation: Griffith University
Country: Australia

Publications

  1. ncbi Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases
    Alistair R R Forrest
    Institute for Molecular Bioscience and ARC Centre in Bioinformatics, University of Queensland, Brisbane, QLD 4072, Australia
    Genome Biol 7:R5. 2006
  2. ncbi Using a 3D virtual muscle model to link gene expression changes during myogenesis to protein spatial location in muscle
    Ashley J Waardenberg
    CSIRO, Food Futures Flagship, Queensland Bioscience Precinct, 306 Carmody Road, St, Lucia, QLD 4067, Australia
    BMC Syst Biol 2:88. 2008
  3. ncbi Alternate transcription of the Toll-like receptor signaling cascade
    Christine A Wells
    Eskitis Institute for Cell and Molecular Therapies, School of Biological and Biomedical Sciences, Griffith University, Brisbane 4111, Australia
    Genome Biol 7:R10. 2006
  4. ncbi NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease
    Anthony L Cook
    National Centre for Adult Stem Cell Research, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Queensland, Australia
    PLoS ONE 6:e21907. 2011
  5. ncbi Identifying co-regulating microRNA groups
    Jiyuan An
    The National Centre for Adult Stem Cell Research, The Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, QLD 4111, Australia
    J Bioinform Comput Biol 8:99-115. 2010
  6. ncbi Disease-specific, neurosphere-derived cells as models for brain disorders
    Nicholas Matigian
    National Centre for Adult Stem Cell Research, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, QLD 4111, Australia
    Dis Model Mech 3:785-98. 2010
  7. ncbi A cross-study transcriptional analysis of Parkinson's disease
    Greg T Sutherland
    National Centre for Adult Stem Cell Research, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Queensland, Australia
    PLoS ONE 4:e4955. 2009
  8. ncbi Phosphoinositide 3-kinase (PI3K(p110alpha)) directly regulates key components of the Z-disc and cardiac structure
    Ashley J Waardenberg
    Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland, 4111, Australia
    J Biol Chem 286:30837-46. 2011
  9. ncbi Inflammation suppressor genes: please switch out all the lights
    Christine A Wells
    Griffith University, Queensland, Australia
    J Leukoc Biol 78:9-13. 2005
  10. ncbi Continued discovery of transcriptional units expressed in cells of the mouse mononuclear phagocyte lineage
    Christine A Wells
    Institute for Molecular Bioscience and ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia
    Genome Res 13:1360-5. 2003

Collaborators

Detail Information

Publications18

  1. ncbi Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases
    Alistair R R Forrest
    Institute for Molecular Bioscience and ARC Centre in Bioinformatics, University of Queensland, Brisbane, QLD 4072, Australia
    Genome Biol 7:R5. 2006
    ..We undertook a systematic study to catalog the variant transcripts of every protein kinase-like and phosphatase-like locus of mouse http://variant.imb.uq.edu.au...
  2. ncbi Using a 3D virtual muscle model to link gene expression changes during myogenesis to protein spatial location in muscle
    Ashley J Waardenberg
    CSIRO, Food Futures Flagship, Queensland Bioscience Precinct, 306 Carmody Road, St, Lucia, QLD 4067, Australia
    BMC Syst Biol 2:88. 2008
    ....
  3. ncbi Alternate transcription of the Toll-like receptor signaling cascade
    Christine A Wells
    Eskitis Institute for Cell and Molecular Therapies, School of Biological and Biomedical Sciences, Griffith University, Brisbane 4111, Australia
    Genome Biol 7:R10. 2006
    ..Functional annotation of variant proteins was assessed in light of inflammatory signaling in mouse primary macrophages, and the expression of each variant transcript was assessed by splicing arrays...
  4. ncbi NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease
    Anthony L Cook
    National Centre for Adult Stem Cell Research, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Queensland, Australia
    PLoS ONE 6:e21907. 2011
    ..Transcriptomic analysis of Patient and Control hONS cells identified the NRF2 transcription factor signalling pathway as the most differentially expressed in Parkinson's disease...
  5. ncbi Identifying co-regulating microRNA groups
    Jiyuan An
    The National Centre for Adult Stem Cell Research, The Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, QLD 4111, Australia
    J Bioinform Comput Biol 8:99-115. 2010
    ....
  6. ncbi Disease-specific, neurosphere-derived cells as models for brain disorders
    Nicholas Matigian
    National Centre for Adult Stem Cell Research, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, QLD 4111, Australia
    Dis Model Mech 3:785-98. 2010
    ..They do not require genetic reprogramming and they can be obtained from adults with complex genetic diseases. They will be useful for understanding disease aetiology, for diagnostics and for drug discovery...
  7. ncbi A cross-study transcriptional analysis of Parkinson's disease
    Greg T Sutherland
    National Centre for Adult Stem Cell Research, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, Queensland, Australia
    PLoS ONE 4:e4955. 2009
    ..Our findings suggest that there is greater concordance in PD whole-genome expression profiling when standardised pathway membership rather than ranked gene list is used for comparison...
  8. ncbi Phosphoinositide 3-kinase (PI3K(p110alpha)) directly regulates key components of the Z-disc and cardiac structure
    Ashley J Waardenberg
    Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan, Queensland, 4111, Australia
    J Biol Chem 286:30837-46. 2011
    ..In summary, PI3K regulates the expression of genes essential for cardiac structure and Z-disc signaling, interacts with melusin, and is critical for Z-disc alignment...
  9. ncbi Inflammation suppressor genes: please switch out all the lights
    Christine A Wells
    Griffith University, Queensland, Australia
    J Leukoc Biol 78:9-13. 2005
    ....
  10. ncbi Continued discovery of transcriptional units expressed in cells of the mouse mononuclear phagocyte lineage
    Christine A Wells
    Institute for Molecular Bioscience and ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia
    Genome Res 13:1360-5. 2003
    ....
  11. ncbi Systems biology of transcription control in macrophages
    Timothy Ravasi
    Scripps NeuroAIDS Preclinical Studies Centre and Department of Bioengineering, Jacobs School of Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Bioessays 29:1215-26. 2007
    ....
  12. ncbi Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis
    Rebecca A Hinshelwood
    Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
    Cancer Res 67:11517-27. 2007
    ....
  13. ncbi Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs
    Norihiro Maeda
    Genome Science Laboratory, Discovery Research Institute, RIKEN Wako Institute, Wako, Japan
    PLoS Genet 2:e62. 2006
    ....
  14. ncbi Genome-wide analysis of mammalian promoter architecture and evolution
    Piero Carninci
    Genome Exploration Research Group, RIKEN Genomic Sciences Center, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan
    Nat Genet 38:626-35. 2006
    ..These data permit genome-scale identification of tissue-specific promoters and analysis of the cis-acting elements associated with them...
  15. ncbi LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action
    David P Sester
    Cooperative Research Centre for Chronic Inflammatory Diseases, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia
    Immunobiology 210:97-107. 2005
    ..This finding also provides a biological relevance to the well-documented ability of macrophage activators to down-modulate surface expression of the CSF-1R...
  16. ncbi Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor
    Michael Rehli
    Department of Hematology and Oncology, University of Regensburg, Germany
    J Immunol 174:7111-22. 2005
    ..Our study also provides a general definition of the transcriptome in alternatively activated mouse macrophages and identifies a large number of novel genes characterizing this cell type...
  17. ncbi Genetic control of the innate immune response
    Christine A Wells
    Institute for Molecular Biosciences, The University of Queensland, Brisbane, QLD, 4072, Australia
    BMC Immunol 4:5. 2003
    ....
  18. ncbi Transcriptional regulatory networks in macrophages
    David A Hume
    ARC Special Research Centre for Functional and Applied Genomics and CRC for Chronic Inflammatory Diseases, Institute for Molecular Bioscience, University of Queensland, Australia
    Novartis Found Symp 281:2-18; discussion 18-24, 50-3, 208-9. 2007
    ....