A J Wigg

Summary

Affiliation: Flinders University
Country: Australia

Publications

  1. ncbi The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis
    A J Wigg
    Department of Gastroenterology, Queen Elizabeth Hospital, Adelaide, South Australia, Australia
    Gut 48:206-11. 2001
  2. ncbi Assessment of cell concentration and viability of isolated hepatocytes using flow cytometry
    Alan J Wigg
    Department of Medical Biochemistry, Flinders University, Bedford Park, South Australia 5042, Australia
    Anal Biochem 317:19-25. 2003
  3. ncbi Maintenance of integrity and function of isolated hepatocytes during extended suspension culture at 25 degrees C
    Alan J Wigg
    Departments of Gastroenterology and Hepatology, Flinders Medical Centre, Flinders University, Adelaide, Australia
    Liver Int 23:201-11. 2003
  4. ncbi Outcomes following liver transplantation for seronegative acute liver failure: experience during a 12-year period with more than 100 patients
    Alan J Wigg
    Liver Unit, Queen Elizabeth Hospital, Birmingham, UK
    Liver Transpl 11:27-34. 2005
  5. ncbi Liver support systems: promise and reality
    Alan J Wigg
    South Australian Liver Transplantation Unit, Flinders Medical Center, Adelaide, South Australia, Australia
    J Gastroenterol Hepatol 20:1807-16. 2005
  6. ncbi Chronic kidney disease following liver transplantation: a South Australian experience
    J Ramachandran
    South Australian Liver Transplant Unit, Flinders Medical Centre, Adelaide, Australia
    Transplant Proc 42:3644-6. 2010
  7. ncbi Inhibition of oxidative stress and apoptosis enables extended maintenance of integrity and function of isolated hepatocytes in suspension
    Alan J Wigg
    Department of Gastroenterology and Hepatology, Flinders Medical Centre, Bedford Park, South Australia, Australia
    J Gastroenterol Hepatol 24:1082-8. 2009
  8. ncbi Current controversies surrounding liver transplantation for hepatocellular carcinoma
    Mauricio F Silva
    Department of Gastroenterology and Hepatology, Flinders University, Adelaide, Australia
    J Gastroenterol Hepatol 25:1217-26. 2010

Collaborators

Detail Information

Publications8

  1. ncbi The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis
    A J Wigg
    Department of Gastroenterology, Queen Elizabeth Hospital, Adelaide, South Australia, Australia
    Gut 48:206-11. 2001
    ..Small intestinal bacterial overgrowth may contribute to the development of non-alcoholic steatohepatitis, perhaps by increasing intestinal permeability and promoting the absorption of endotoxin or other enteric bacterial products...
  2. ncbi Assessment of cell concentration and viability of isolated hepatocytes using flow cytometry
    Alan J Wigg
    Department of Medical Biochemistry, Flinders University, Bedford Park, South Australia 5042, Australia
    Anal Biochem 317:19-25. 2003
    ..The techniques are simple, rapid, and more accurate than manual cell counting and trypan blue staining and the results are not affected by protein-containing media...
  3. ncbi Maintenance of integrity and function of isolated hepatocytes during extended suspension culture at 25 degrees C
    Alan J Wigg
    Departments of Gastroenterology and Hepatology, Flinders Medical Centre, Flinders University, Adelaide, Australia
    Liver Int 23:201-11. 2003
    ..These observations demonstrate the robust nature of mildly hypothermic isolated hepatocytes in suspension and encourage further studies re-examining the feasibility of using this cell preparation in bioartificial livers...
  4. ncbi Outcomes following liver transplantation for seronegative acute liver failure: experience during a 12-year period with more than 100 patients
    Alan J Wigg
    Liver Unit, Queen Elizabeth Hospital, Birmingham, UK
    Liver Transpl 11:27-34. 2005
    ..In conclusion, we found that donor and recipient factors identify patients who have a high chance of early death after transplantation...
  5. ncbi Liver support systems: promise and reality
    Alan J Wigg
    South Australian Liver Transplantation Unit, Flinders Medical Center, Adelaide, South Australia, Australia
    J Gastroenterol Hepatol 20:1807-16. 2005
    ....
  6. ncbi Chronic kidney disease following liver transplantation: a South Australian experience
    J Ramachandran
    South Australian Liver Transplant Unit, Flinders Medical Centre, Adelaide, Australia
    Transplant Proc 42:3644-6. 2010
    ..Mild and moderate CKD are common post-OLT. The development of severe CKD, which can be predicted early in the post-OLT period, is strongly associated with an increased mortality rate...
  7. ncbi Inhibition of oxidative stress and apoptosis enables extended maintenance of integrity and function of isolated hepatocytes in suspension
    Alan J Wigg
    Department of Gastroenterology and Hepatology, Flinders Medical Centre, Bedford Park, South Australia, Australia
    J Gastroenterol Hepatol 24:1082-8. 2009
    ..However, maintenance of isolated hepatocyte suspensions in conventional media leads to rapid loss of cell integrity. The aim of this study was to develop a modified medium to better maintain hepatocyte integrity...
  8. ncbi Current controversies surrounding liver transplantation for hepatocellular carcinoma
    Mauricio F Silva
    Department of Gastroenterology and Hepatology, Flinders University, Adelaide, Australia
    J Gastroenterol Hepatol 25:1217-26. 2010
    ..In the interim transplant clinicians must restrict the use of these therapies to those patients who are most likely to benefit from them...