Research Topics
Genomes and GenesSpecies | Brian D TaitSummaryAffiliation: Australian Red Cross Blood Service Country: Australia Publications
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Detail Information
Publications
HLA class I expression on human cancer cells. Implications for effective immunotherapyB D Tait
Victorian Transplantation and Immunogenetics Service Australian Red Cross Blood Services, Parkville, Victoria, Australia
Hum Immunol 61:158-65. 2000..The identification of appropriate monoclonal antibody reagents for class I expression and techniques used on different kinds of tissue sections will be a component of the forthcoming 13th International Histocompatibility Workshop...- Solid phase HLA antibody detection technology--challenges in interpretationB D Tait
National Transplant Services, Australian Red Cross Blood Service, Melbourne, Australia
Tissue Antigens 76:87-95. 2010..The advantages of bead technology for HLA antibody determination and the technical issues requiring resolution are the subject of this review... - In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtypeHector Chinoy
Rheumatic Diseases Centre, Hope Hospital, Salford, UK
Arthritis Res Ther 8:R13. 2006..In conclusion, these findings support the notion that myositis patients with differing myositis serology have different immunogenetic profiles, and that these profiles may define specific myositis subtypes... - Review article: Luminex technology for HLA antibody detection in organ transplantationBrian D Tait
Victorian Transplantation and Immunogenetic Service, Australian Red Cross Blood Service, Parkville, Victoria, Australia
Nephrology (Carlton) 14:247-54. 2009..Luminex technology will permit a re-evaluation of the role of HLA antibodies in both early and late antibody-mediated rejection... - 14th International HLA and Immunogenetics Workshop: report on HLA expression and cancerB D Tait
Victorian Transplantation and Immunogenetic Service, Melbourne, Australia
Tissue Antigens 69:245-7. 2007 - Allocation of cadaver donor kidneys in AustraliaBrian D Tait
Victorian Transplantation and Immunogenetics Service, Australian Red Cross Blood Service, Royal Melbourne Hospital, Parkville Victoria, Australia
Transplantation 77:627-9. 2004..Kidneys that do not reach the level of matching required for national allocation are transplanted in the donor state using both matching and waiting time criteria, which caters to minority groups with rare HLA types... - Solid phase assays for HLA antibody detection in clinical transplantationBrian D Tait
Victorian Transplantation and Immunogenetic Service, Australian Red Cross Blood Service, 2nd Floor Rotary Bone Marrow Research Building, c o Royal Melbourne Hospital, Grattan St, Parkville 3050, Australia
Curr Opin Immunol 21:573-7. 2009..The role in allograft rejection of antibody titre and non-complement fixing antibodies, which are also detected by these methods, are areas currently under consideration... - The ever-expanding list of HLA alleles: changing HLA nomenclature and its relevance to clinical transplantationBrian D Tait
National Transplant Services, Australian Red Cross Blood Service, Melbourne, Australia
Transplant Rev (Orlando) 25:1-8. 2011.... - Human leukocyte antigen mismatch and other factors affecting cryopreserved allograft valve functionCheng Hon Yap
Department of Cardiothoracic Surgery, St Vincent s Hospital, Melbourne, Australia
Heart Surg Forum 11:E42-5. 2008..Recipient age remained the strongest predictor of valve dysfunction. These results indicate that allograft ischemic times should be minimized... - Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivityDiana Chessman
Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
Immunity 28:822-32. 2008.... - Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasionDanielle Zernich
Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
J Exp Med 200:13-24. 2004..These findings unveil a new layer of MHC polymorphism that affects the generic pathway of Ag loading, revealing an unsuspected evolutionary trade-off in selection for optimal HLA class I loading versus effective pathogen evasion... - A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosisJudith Field
Florey Neuroscience Institutes, University of Melbourne, Melbourne, Victoria, Australia
PLoS ONE 5:e13454. 2010..It is correlated with the HLA-DPB1*03:01 allele, which has been implicated previously in MS in smaller studies. Further genotyping in large datasets is required to confirm and resolve this association... - Anti-HLA antibodies after cryopreserved allograft valve implantation does not predict valve dysfunction at three-year follow upCheng Hon Yap
Department of Cardiothoracic Surgery, St Vincent s Hospital, Melbourne, PO Box 2900, Fitzroy, VIC 3065, Australia
J Heart Valve Dis 15:540-4. 2006..As the cause of allograft heart valve degeneration is poorly understood, the study aim was to investigate the host antibody response to allograft valve implantation... - HLA DPA1, DPB1 alleles and haplotypes contribute to the risk associated with type 1 diabetes: analysis of the type 1 diabetes genetics consortium familiesMichael D Varney
Department of Surgery, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, USA
Diabetes 59:2055-62. 2010..To determine the relative risk associated with DPA1 and DPB1 alleles and haplotypes in type 1 diabetes... - Identification of a novel DPB1* allele (DPB1*6901) and the occurrence of HLA haplotypes that extend to DPB1M D Varney
Victorian Transplantation and Immunogenetics Service, Australian Red Cross Blood Services, Parkville
Tissue Antigens 55:188-90. 2000.... - The effect of folinic Acid on methylenetetrahydrofolate reductase polymorphisms in methotrexate-treated allogeneic hematopoietic stem cell transplantsNicholas M Murphy
Department of Pharmaceutical Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia
Biol Blood Marrow Transplant 18:722-30. 2012..Use of FA following transplantation should be reconsidered in the context of patient and donor MTHFR genotypes... - HLA genes associated with autoimmunity and progression to disease in type 1 diabetesB D Tait
Victorian Transplantation and Immunogenetics Service, Australian Red Cross Blood Service, Melbourne, Victoria, Australia
Tissue Antigens 61:146-53. 2003.... - A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognitionWhitney A Macdonald
Dept. of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
J Exp Med 198:679-91. 2003..The findings suggest that these closely related class I genes are maintained in diverse human populations through their differential impact on the selection of peptide ligands and the T cell repertoire... - Quantitative and functional diversity of cross-reactive EBV-specific CD8+ T cells in a longitudinal study cohort of lung transplant recipientsNicole A Mifsud
Department of Medicine, Monash University, Central Clinical School, The Alfred Hospital, Melbourne, Victoria, Australia
Transplantation 90:1439-49. 2010.... - The rising incidence of type 1 diabetes is accounted for by cases with lower-risk human leukocyte antigen genotypesSpiros Fourlanos
Autoimmunity and Transplantation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Diabetes Care 31:1546-9. 2008..To examine these possibilities, human leukocyte antigen (HLA) class II DRB1 genes known to confer risk for type 1 diabetes were analyzed in relation to year of birth and age at diagnosis over the last five decades... - Immunodominance hierarchies and gender bias in direct T(CD8)-cell alloreactivityN A Mifsud
Department of Microbiology and Immunology, The University of Melbourne, Royal Parade, Parkville, Victoria, Australia
Am J Transplant 8:121-32. 2008.... - SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in TasmaniansR K Burfoot
Howard Florey Institute, University of Melbourne, Melbourne, Victoria, Australia
Tissue Antigens 71:42-50. 2008..We have therefore identified plausible candidates for the causal MS susceptibility allele, and although not conclusive at this stage, our data provide suggestive evidence for multiple class I MS susceptibility genes... - HLA expression and cancer--14th IHIWS immunohistochemistry quality control exercise exchange resultsS F Chew
Victorian Transplantation and Immunogenetic Service, Melbourne, Australia
Tissue Antigens 69:248-51. 2007..It is suggested that further exercises are conducted as part of future collaborative activities in order to further characterise areas of variability between IH performance and interpretation of results... - Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitusG Morahan
Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Victoria, Australia
Science 272:1811-3. 1996..These results indicate the existence of a gene that acts at an early stage in IDDM development, screening for which may identify a specific subset of at-risk individuals... - Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B alleleG Morahan
The Walter and Eliza Hall Institute of Medical Research, PO Royal Melbourne Hospital, Victoria, Australia
Nat Genet 27:218-21. 2001..The IL12B 3' UTR alleles showed different levels of expression in cell lines. Variation in IL-12p40 production may influence T-cell responses crucial for either mediating or protecting against this and other autoimmune diseases... - Nucleotide sequences of the HLA-DRw12 and DRw8 B1 chains from an Australian aborigineR M O'Brien
Burnet Clinical Research Unit, Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
Hum Immunol 34:147-51. 1992..DRB RFLP studies on this cell line using the Taq I restriction enzyme indicated bands previously described for the DRw8 and DRw12 haplotypes... - Interferon-gamma and interleukin-4 gene polymorphisms in Caucasian idiopathic inflammatory myopathy patients in UKHector Chinoy
The University of Manchester Rheumatic Diseases Centre, Salford M6 8HD, UK
Ann Rheum Dis 66:970-3. 2007..To determine whether interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) genes confer susceptibility for the idiopathic inflammatory myopathies (IIMs)...